Volume 14, Issue 54 (4-2007)                   RJMS 2007, 14(54): 45-51 | Back to browse issues page

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Poormoghim H, Mazaheri Tehrani M. A Case Report of Sarcoidosis with Sjogren-Like Symptoms. RJMS 2007; 14 (54) :45-51
URL: http://rjms.iums.ac.ir/article-1-698-en.html
Abstract:   (10307 Views)

    Introduction: Sarcoidosis is a chronic granulomatous disease of unknown origin characterized by the presence of non-caseating epitheloid cell granulomas in multiple organs such as lymph nodes, lungs, spleen, liver, skin, and salivary and lacrimal glands. The diagnosis is established when clinical and radiologic findings are supported by histologic evidence of non-caseating granulomas. Sarcoidosis shares several of the extragrandular features of sjogren syndrome as well as the involvement of the salivary and lacrimal glands, which makes it difficult to differentiate between the two diseases based on clinical grounds alone. Case Report: This article represents a 19-year-old lady who presented with parotid enlargement, dry mouth and dry eyes since 3 years ago. Chest x-ray was normal but HRCT(High Resolution CT-scan) revealed a bilateral ground glass lesion. Bronchial biopsy reported chronic granulomatous pneumonia with non-caseating granulomas. Angiotensin converting enzymes(ACE) level was elevated. The PPD skin test and acid fast smear were negative. The test results for anti-Ro, anti-La, and anti-nuclear antibodies(ANA) were negative too. Conclusion: Finally, the patient was diagnosed as a case of sarcoidosis and went under treatment. During the follow-up visits, the signs and symptoms disappeared and a normal ACE level was reported after 6 months. Since sarcoidosis with sjogren-like manifestations is unusual, we decided to present this case.

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Type of Study: case report | Subject: Rheumatology

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