Volume 28, Issue 10 (12-2021)                   RJMS 2021, 28(10): 0-0 | Back to browse issues page

Research code: R.IAU.SARI.REC.1397.8
Ethics code: R.IAU.SARI.REC.1397.8
Clinical trials code: R.IAU.SARI.REC.1397.8

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dehghanipour F, barari A, abdi A, farzanegi P. The effect of resveratrol supplementation and aerobic exercise on serum levels of activin A and TGF-β in rats with non-alcoholic fatty liver disease. RJMS. 2021; 28 (10)
URL: http://rjms.iums.ac.ir/article-1-6720-en.html
Islamic Azad University , alireza54.barari@gmail.com
Abstract:   (97 Views)
Introduction: The aim of this study was to investigate The effect of aerobic exercise and resveratrol supplementation on serum levels of activin A and TGF-β in rats with non-alcoholic fatty liver disease.Methodology:Fifty-six old male Wistar rats  were assigned to one healthy control group and seven following experimental NAFLD groups . Rats in the RSV groups were given 25 mg/kg of body weight resveratrol daily by intraperitoneal injection. Exercised perform for 5 days per week in 8 weeks. Data were analyzed by One way ANOVA and Tukeychr('39')s post hoc test at the P<0.05.findings: Fatty liver increased activin A and TGF-β levels in the patient group and aerobic exercise and red grape extract (resveratrol) significantly decreased serum levels of Activin A and TGF-β in aged non-alcoholic fatty liver rats in the experimental groups. Conclusion:The findings of the present study showed that serum levels of TGF-β and activin A were increased in rats with NFALD; it is likely that the reason for the increased levels of cytokines may be related to the cirrhotic process itself. The results
Type of Study: Research | Subject: Exercise Physiology

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