Razi Journal of Medical Sciences

  Lung cancer is still the main cause of death in cancer diseases, both in men and women. The high incidence and poor prognosis of the lung cancer makes it a major health priblem in the last few decades. Determination of frequency of different histopathologic types of primary lung cancer has great importance in creating integrated treatment programs and to recognize the effective factors causing the disease. Specially there is not enough information about this subjects in Iran. This study has been designed to fulfill the above requirements. This is an observational, descriptive and cross-sectional study and explanation using a sample volume of 384 patients. Used Sampling method was a multistage one. At first, Tehran was divided into 5 areas. After that one hospital was chosen in each area. Finally, samples are related to years 1991-1998 from these hospitals (Emam Khomainie, Hazrat Rasul-e Akram, Firoozgar, Labbafeenejad, Massih Daneshvari and Haft-e Tir) were collected.

  From 384 samples, 77.1% were male and 22.9% were famale. The average age of those suffering, ranged from 63.01 ± 1.34 years so most of those suffering were in their 7 th decade of life. From them 57% were cigarette smokers and 13.22% were opioid users. In the smokers group, the averge cigarette consumption were 32.13 ± 3.6 packs per year and this would be increased with age. The most common type of malignancy were as following: squamous cell carcinoma (51.6%), adnocarcinoma (16.4%), small cell carcinoma (14.3%), large cell carcinoma, carcinoid tumor, bronchial gland carcinoma and adensquamous carcinoma. There was a meaningful relationship between smoking habit and incidence of SCC and adnocarcinoma (P=0.000). There was also a meaningful relationship between sex and type of malignancy (P=0.000). The most common signs, were cough, dyspnea, hemoptysis and chest pain.

  As there are frequent types of malignant lung cancer, the results are considerably different from those are obtained from other countries. This difference has been confirmed by other similar studies carried out in the country. This suggest that the probability of these difference is related to different risk factors in our country from others. These finding makes obligate us to have effective plan for recognition of them for prevention purposes.