Volume 15 - Autumn,Winter                   RJMS 2009, 15 - Autumn,Winter: 133-139 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Tabatabaee A, Farhadi M, Noorbaksh S, Shekarabi M, Shamshiri A, Alirezaie N et al . Evaluation of Mycoplasma and Chlamydia Infection with PCR Method and Serology in Patients with Nasal Polyps and Normal Subjects. RJMS 2009; 15 :133-139
URL: http://rjms.iums.ac.ir/article-1-1072-en.html
Abstract:   (9015 Views)

    Background and Aim: Inflammation is relatively a documented pathogenic cause of chronic rhinocynositis and nasal polyps, but the definite causes are still unknown. Among the infective causes, we decided to evaluate Mycoplasma and Chlamydia, the two major pathogens in respiratory tract diseases, as a potential etiologies in nasal polys.

Materials and Methods: In a descriptive-analytic cross-sectional study, 51 patients with nasal polyp and 19 healthy persons (with nasal fracture) who had referred to

Hazrat-e-Rasool

Akram

Hospital were enrolled in the study. Blood sample for ELISA and nasal polyp tissue (in control group a specimen from inferior nasal turbinate mucosa) for PCR tests were sent to the laboratory. Descriptive measures, Chi-square and Mac Nemar tests and Kappa agreement statistics were used for statistical analysis.

Results: Positive results for IgM, IgG and PCR for Chlamydia were 9.8%, 47.1% and 7.8% in patients and 0%, 47.4% and 0% in control group, respectively. The differences between the groups were not statistically significant. Similarly for Mycoplasma, the above mentioned results were 15.7%, 68.6% and 19.6% in patients and 15.8%, 47.4% and 0% in control group, respectively. According to IgG and PCR results, the differences between two groups seems to be significant (P =0.10 and 0.05 respectively).

Conclusion: Between the two evaluated bacteria in this study, mycoplasma may have significant correlation with nasal polyp formation. However further studies with larger sample size and considering more confounding factors are needed.

Full-Text [PDF 218 kb]   (4527 Downloads)    
Type of Study: Research | Subject: ENT

Add your comments about this article : Your username or Email:
CAPTCHA

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Razi Journal of Medical Sciences

Designed & Developed by : Yektaweb