Volume 30, Issue 6 (9-2023)                   RJMS 2023, 30(6): 0-0 | Back to browse issues page

Research code: 0
Ethics code: IR.IUMS.FMD.REC.1401.086
Clinical trials code: 0

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Aghajani Delavar M, Hosseinzadeh Z, Khoshnezhad Ebrahimi H, Esmaeilian S. Investigating the relationship between vitamin D levels and upper urinary tract infections (UTI) in children between 2 months and 6 years old. RJMS 2023; 30 (6)
URL: http://rjms.iums.ac.ir/article-1-7936-en.html
Department of Pediatrics, Aliasghar children’s Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. , zahra.hosseinzade.92@gmail.com
Abstract:   (321 Views)
Introduction: Urinary tract infection in children has a high prevalence and can cause high complications and morbidity. In addition, according to some studies, vitamin D can improve the immune system and reduce the possibility of urinary tract infection. But this effect has not been definitely determined, and on the other hand, the use of vitamin D supplements is sometimes one of the causes of kidney stones. Therefore, considering the importance of this issue, the purpose of this study is to investigate the relationship between vitamin D level and upper urinary tract infections (UTI) in children between 2 months and 6 years old in selected hospitals of Iran University of Medical Sciences in 1400. Materials and methods: This case-control study was conducted on 50 children with the first episode of febrile urinary tract infection and 50 normal children without UTI aged 2 months to 6 years who visited Ali Asghar Hospital. Inclusion criteria for children with UTI included: (1) signs and symptoms of the disease including fever (greater than or equal to 38 degrees), abdominal pain, dysuria, anorexia and nausea, (2) pyuria, (3) culture positive urine, (4) no history of taking vitamin D supplements during the last 12 months, (5) no malnutrition or obesity, and (6) no kidney disorders. After selecting the patient and control groups based on the study inclusion criteria, a checklist was prepared in which the demographic information of the individuals, including age and sex, was recorded. Also, the results related to the analysis of routine laboratory tests such as CBC, WBC, PMN, ESR, and CRP, BUN, ALP, calcium and blood phosphorus were also measured and recorded for the patients. Conclusion: In the present study, it was found that the level of vitamin D is significantly lower in people with UTI. However, there was no significant relationship between vitamin D level and gender and age. Also, vitamin D level was not significantly related to other tests including WBC, PMN, creatinine, BUN, ESR, CRP, alkaline phosphatase, phosphorus, and calcium in any of the groups. In addition, it was found that vitamin D deficiency (less than 30 nmol/liter) doubles the chance of UTI. Keywords: u
Type of Study: Research | Subject: Pediatric Disease

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