1.Introduction
Electrolyte imbalance is one of the important factors in the occurrence of cardiac arrhythmias (9) and in order to prevent the occurrence of these arrhythmias, it is necessary to measure serum electrolytes regularly after the operation and examine the patient for signs of decrease or increase in potassium, sodium and calcium. take (10). In connection with achieving the above goal, the amount of liquid absorption and excretion should be accurately measured and recorded. In order to determine the adequacy of hydration and cardiac output, the central venous pressure, blood pressure, serum electrolytes and, if possible, the patient's weight should be monitored regularly, and the patient should be carefully monitored for signs of hypokalemia, hyperkalemia, hyponatremia (sodium depletion) and hypocalcemia (calcium depletion). be taken care of Any signs or symptoms of dehydration, excess fluid accumulation or electrolyte imbalance should be reported to the doctor immediately (11).
Considering the high prevalence of cardiovascular diseases and considering that hypothermia is a therapeutic intervention in these patients and also considering the diversity and dispersion of complications and the difference in the percentage of their occurrence in patients undergoing heart surgery in studies, and from there After reviewing the research conducted inside and outside the country, no research was found on the subject, the researcher is trying to answer the question whether hypothermia has an effect on electrolyte changes in patients undergoing CABG surgery at Hazrat Fatemeh Zahra Sari Hospital in 2018. No?
2.Method
The present study was conducted as a single-blind randomized clinical trial on 60 adult patients who were candidates for coronary artery bypass surgery, who were randomly divided into two groups of 30 people. The objectives and method of the study were explained to the patients and written informed consent was obtained. At the beginning of the study, the amount of sodium, potassium and calcium electrolytes of patients who were to undergo open heart surgery were recorded. All patients were operated on by a cardiac surgeon in Hazrat Fatima Zahra Sari Hospital. Arterial pressure of all patients was controlled through the radial artery and they underwent general anesthesia with the same drugs. And each of them performed their own operation, after the completion of the operation and transfer to the ICU, special checklists containing demographic information and electrolyte changes were completed. The desired electrolytes were measured and noted on the day after surgery and the day of discharge from ICU. Finally, after data collection, the information was analyzed using SPSS 21 statistical software and descriptive statistics (mean and standard deviation) and inferential statistics (independent t test and one-way analysis of variance).
3.Results
The comparison of the sodium level shows that in the comparison of the two groups, the sodium level is different in the two groups only one day after surgery (P=0.008) and there is a statistically significant difference in such a way that the sodium level in the hypothermic group is higher than in the northermic group. Is. Comparison of sodium level by groups and by time was significant only in the hypothermic group (P=0.006) and in the normothermic group, this difference was not significant by time.
The comparison of potassium level shows that in the comparison of the two groups, only one day after the surgery, the potassium level in the two groups is different (p=0.017) and there is a statistically significant difference such that the potassium level in the hypothermic group is higher than the northermic group. Is. The comparison of potassium level by groups and by time was significant only in the hypothermic group (p=0.018) and in the normothermic group, this difference was not significant by time.
The comparison of calcium level shows that the calcium level was not different in the two groups at any time (P<0.05) and there was no statistically significant difference. The comparison of calcium levels by groups and by time showed that there is a significant difference in calcium levels by time in both groups (p<0.05) so that the calcium level one day before surgery was higher than the other two times.
4.Discussion
Based on the results of the present study, the level of sodium and potassium in the two groups is different only one day after surgery, and there is a statistically significant difference; Sodium and potassium levels were higher in the hypothermic group than in the northermic group one day after surgery. These values are not significantly different on the day of discharge from ICU and before surgery. The comparison of sodium and potassium levels by groups and by time was significant only in the hypothermic group, which increased and then decreased on the day after the operation. There was no significant difference in the level of calcium in the two groups; However, the comparison of calcium level by groups and by time showed that this value has a significant difference in both groups, in such a way that the calcium level was higher one day before surgery than the other two times.
In this regard, Haddadzadeh et al. (2012) conducted a study titled comparing complications after normothermic and hypothermic heart surgery. The sodium level in the hypothermic group was higher than the normothermic group, and the potassium level was higher in the normothermic group than the hypothermic group, but this difference was not significant. These results were inconsistent with the results of the present study; In such a way that there was no significant difference between sodium and potassium levels after the operation in the two groups (5). The reason for the difference in the results of the present study and the study of Haddadzadeh et al. can be attributed to the difference in the background variables of the patients, the time of measuring the levels of electrolytes, and the procedures performed before and after heart surgery.
Shahidi et al. (2019) conducted a study under the title of hypomagnesemia and imbalance of other electrolytes in children's open and closed heart surgery. The calcium level in each group decreased significantly on the second and third day after surgery compared to before surgery, but the calcium level of the two groups did not differ significantly, which was consistent with the present study. . The level of sodium and potassium in both groups decreased significantly on the second and third day compared to before the operation, which was inconsistent with the present study. A decrease in these factors was observed during the second and third days after surgery, but there was no significant difference between them in the two groups. The difference in the results of this study with the current study can be due to the difference in the age of the participants and the different measures taken for them (19).