Research code: IR.UT.SPORT.REC.1400.52
Ethics code: IR.UT.SPORT.REC.1400.52
Clinical trials code: IR.UT.SPORT.REC.1400.52
Department of Exercise Physiology, Faculty of Physical Education and Sport Science, University of Tehran, Tehran, Iran , aakbarnejad@ut.ac.ir
Abstract: (431 Views)
Introduction: the current study aimed to investigate the therapeutic and improving effects of oral consumption of grape seed extract (Viis vinifera) with and without aerobic exercise on the some of the most important cardiovascular and metabolic parameters levels in obese middle-aged women with type 2 diabetes.
Methods: 36 women with diabetes as the available sample were purposefully selected and randomly divided into four groups (9 people in each group): 1) exercise+ grape seed extract supplement, 2) exercise + placebo, 3) supplement of grape seed extract and 4) placebo. Participants performed four weeks’ aerobic training (5 days a week) with an intensity of 65-75% of the reserve heart rate. The supplementations group received one grape seed extract capsule and the placebo group consumed starch powder in capsules (the same color and shape as the grape seed capsules).
Results: The results of dependent t-test showed that levels of glucose, insulin, LDL-C, VCAM-1, ICAM1, CRP and homocysteine were significantly decreased and HDL-C were significantly increased in the post-test compared to the pre-test (P <0.05). A significant decrease in glucose, insulin, LDL-C, VCAM-1, ICAM1, CRP and homocysteine levels and a significant increase in HDL-C levels was observed in the exercise supplement, exercise placebo and supplement groups compared to the placebo group (P <0.05).
Conclusion: It seems that consumption of grape extract as a method of improving cardiovascular and metabolic parameters solely can have a positive effect on the control of diabetes. Although when combined with aerobic training the effect gets better.
Methods: 36 women with diabetes as the available sample were purposefully selected and randomly divided into four groups (9 people in each group): 1) exercise+ grape seed extract supplement, 2) exercise + placebo, 3) supplement of grape seed extract and 4) placebo. Participants performed four weeks’ aerobic training (5 days a week) with an intensity of 65-75% of the reserve heart rate. The supplementations group received one grape seed extract capsule and the placebo group consumed starch powder in capsules (the same color and shape as the grape seed capsules).
Results: The results of dependent t-test showed that levels of glucose, insulin, LDL-C, VCAM-1, ICAM1, CRP and homocysteine were significantly decreased and HDL-C were significantly increased in the post-test compared to the pre-test (P <0.05). A significant decrease in glucose, insulin, LDL-C, VCAM-1, ICAM1, CRP and homocysteine levels and a significant increase in HDL-C levels was observed in the exercise supplement, exercise placebo and supplement groups compared to the placebo group (P <0.05).
Conclusion: It seems that consumption of grape extract as a method of improving cardiovascular and metabolic parameters solely can have a positive effect on the control of diabetes. Although when combined with aerobic training the effect gets better.
Type of Study: Research |
Subject:
Exercise Physiology
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