Background & Aim: In a variety of diseases thumb opposition is absent. Opponensplasty is the transfer of tendon to thumb in order to regain opposition in hands. This operation is perfomed with different tendons and operation techniques results of surgeries are different with various surgical techniques. In this study result of these operations in different patients was assessed in Shafa Rehabilitation Center, between 1984-2005. The aim was to evaluate the results of this type of surgery in different diseases and also to determine the procedure that has the best results. Patients and Method: Ninty five patients with opponensplasty were assessed for results of surgery in Shafa Yahyaeeyan hospital between 1984-2005. Because of varity of diseases such as polio, CP etc. these patient were unable to perform thumb opposition and underwent surgery with different techniques. In this study long term results of these surgeries were assessed with evaluation of patient satisfaction and thumb opposition. Results: Among CP patients, 8(75%) demonestrated good or excellent results. Among Polio patients(35 cases), response was weaker and 62% showed good or excellent results. Meanwhile Burkhalter technique was excellent or good in 80.6% when compared with other methods it was better. Conclusion: Result of opponensplasty was good or excellent in more than 70% of cases Burkhalter technique was better. Results of surgery was better in traumatic disorders as compared to other diseases.