Volume 28, Issue 10 (12-2021)                   RJMS 2021, 28(10): 0-0 | Back to browse issues page

Research code: IR.SUMS.REC.1398.784
Ethics code: IR.SUMS.REC.1398.784
Clinical trials code: IR.SUMS.REC.1398.784

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Salehpoor G, Rahimi C, Mohammadi N, Asadi-Pooya A. Comorbidity of Sleepiness and Seizures: Evaluation of Cognitive Function, Quality and Severity of Pain and Disease Severity Markers. RJMS. 2021; 28 (10)
URL: http://rjms.iums.ac.ir/article-1-6488-en.html
Shiraz University , crahimi@hotmail.com
Abstract:   (78 Views)
Background: Sleepiness is one of the most important complaints of patients with seizures that have a complex interaction with each other. The comorbidity of the two can affect a wide range of cognitive functions, pain appearances, and disease indicators, many of which remain ambiguous. Therefore, the aim of the present study was to investigate the comorbidity of sleepiness and seizures on cognitive functions, quality and severity of pain and disease severity markers.
Methods: In a case-control study, 68 patients with seizures (in two groups with sleepiness and no sleepiness) were selected by purposive sampling and using comprehensive list of demographic and clinical variables, Stanford Sleepiness Scale, Montreal Cognitive Assessment, McGill Pain Questionnaire and Visual Analogue Scale were examined. Data were analyzed by independent student t-test, multivariate and univariate analysis of covariance with control of possible confounding variables, chi-square, Fisherchr('39')s exact and Mann–Whitney U.
Results: Analyses after controlling confounding variables showed that there was a significant difference between the two groups of patients with seizures with and without sleepiness in the components of language, abstraction, delayed recall, total Montreal score, pain sensory perception, pain evaluation, total McGill score, vocabulary frequency and pain intensity. Also, patients with sleepiness showed a higher frequency than their counterparts in seizure occurrence, comorbidity of physical illness, histories of psychiatric diagnosis, and simultaneous use of AEDs and psychiatric medications.
Conclusion: Sleepiness is associated with cognitive deficits, increased pain experience and worsening of the disease.
Type of Study: Research | Subject: Neurology

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