Volume 30, Issue 2 (4-2023)
RJMS 2023, 30(2): 0-0 |
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Research code: 234578
Ethics code: IR.IAU.ARAK.REC.1401.093
Clinical trials code: 234578
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Nomoradi H, Mohajerani H. Study of the relationship between the polymorphism of the gene responsible for serotonin transporter and a history of violent crime. RJMS 2023; 30 (2)
URL: http://rjms.iums.ac.ir/article-1-6411-en.html
URL: http://rjms.iums.ac.ir/article-1-6411-en.html
Islamic Azad University of Arak , hr-mohajerani@arak-iau.ac.ir
Abstract: (127 Views)
Introduction: There is a serious disagreement between researchers about the genetic basis of crime. Some biologists and clinical criminologists deny the existence of a chromosome or a crime. Some forensic psychiatrists believe that certain alleles of genes are directly or indirectly involved in the commission of violent acts. The aim of the present study was to determine the relationship between the relative frequency of certain alleles of the gene responsible for transporter serotonin and a history of violent crime.
Materials and Methods: Perpetrators of violent crimes In this study, by the available sampling method, 50 people were selected from among the thieves of violent behaviors, including bags and mobile phones. After venous blood sampling, DNA was extracted from venous blood. Using appropriate primers, the 5HTTLPR and VNTR-17 (STin2) polymorphisms in the 5HTT gene were examined by AFLP analysis.
Results: For the 5HTTLPR gene, the highest frequency belonged to the SS SS allele. Regarding the VNTR-17 gene (STin2), the highest frequency for the allele was 12.10. In the next position, 12.12, and finally 10.10 was the lowest relative frequency (24%).
Conclusion: Although the pattern of relative abundance of gene alleles responsible for serotonin transporter production in the present study is very similar to the gene pattern of individuals with mental disorders leading to violent criminal behaviors, a causal relationship between the frequency of specific alleles of this gene and the occurrence of such behaviors cannot be deduced.
Materials and Methods: Perpetrators of violent crimes In this study, by the available sampling method, 50 people were selected from among the thieves of violent behaviors, including bags and mobile phones. After venous blood sampling, DNA was extracted from venous blood. Using appropriate primers, the 5HTTLPR and VNTR-17 (STin2) polymorphisms in the 5HTT gene were examined by AFLP analysis.
Results: For the 5HTTLPR gene, the highest frequency belonged to the SS SS allele. Regarding the VNTR-17 gene (STin2), the highest frequency for the allele was 12.10. In the next position, 12.12, and finally 10.10 was the lowest relative frequency (24%).
Conclusion: Although the pattern of relative abundance of gene alleles responsible for serotonin transporter production in the present study is very similar to the gene pattern of individuals with mental disorders leading to violent criminal behaviors, a causal relationship between the frequency of specific alleles of this gene and the occurrence of such behaviors cannot be deduced.
Type of Study: Research |
Subject:
Physiology
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