Volume 26, Issue 12 (2-2020)                   RJMS 2020, 26(12): 149-155 | Back to browse issues page

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rhimi M, azarbayjani M A, peeri M, farzanegi P. Effects of aerobic training and vitamin D on HSP70 gene expression in lung tissue of rats exposed to hydrogen peroxide. RJMS 2020; 26 (12) :149-155
URL: http://rjms.iums.ac.ir/article-1-6030-en.html
Islamic Azad University , m_azarbayjani@iauctb.ac.ir
Abstract:   (2056 Views)
Background: The purpose of present study was to investigate the effect of aerobic training and vitamin D on the gene expression of HSP70 in the lung tissue of rats exposed to oxygenated water.
Methods: In this experimental study, 30 male male Wistar rats were randomly divided into five groups of six each: oxygenated water, oxygenated water plus vitamin D, oxygenated water plus aerobic training, and oxygenated water plus aerobic training plus vitamin D. The groups underwent the respective interventions for 8 weeks. HSP70 gene expression were measured by real time and PCR.
Results: The aerobic training and vitamin D a lonely caused significant decrease in gene expression of HSP70 compared to oxygenated water (P<0.05) but the interaction effect of aerobic training and vitamin D interactiondid not significant.
Conclusion: It seems that aerobic training and vitamin D induce improve of oxidative stress and inflammation in lung tissue.
 
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Type of Study: Research | Subject: Exercise Physiology

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