Volume 26, Issue 2 (5-2019)
RJMS 2019, 26(2): 39-49 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
hooshmand moghadam B, Eskandari M, Bijeh N, Mohammadnia Ahmadi M, Norouzi J. Evaluation of the Effect of short-term Barberry Juice Supplementation on humoral immune response in active girls following exhaustive exercise activity: A randomized double-blind clinical trial. RJMS 2019; 26 (2) :39-49
URL: http://rjms.iums.ac.ir/article-1-5579-en.html
URL: http://rjms.iums.ac.ir/article-1-5579-en.html
Babak Hooshmand moghadam 
, Mozhgan Eskandari , Nahid Bijeh , Mohsen Mohammadnia Ahmadi , Javad Norouzi
, Mozhgan Eskandari , Nahid Bijeh , Mohsen Mohammadnia Ahmadi , Javad Norouzi
Ferdowsi University of Mashhad, Mashhad, Iran , babak.hooshmand@mail.um.ac.ir
Abstract: (11145 Views)
Background: Regarding the physiological and immunological changes of the human body following acute exhaustive activity and the evidence in traditional medicine of the effects of barberry on the strengthening of the immune system, the aim of this study was evaluation of the effect short-term barberry juice supplementation on the response of immunoglobulin A, G, M and cortisol in active girls following exhaustive exercise activity.
Methods: In this clinical trial study, 20 healthy young girls (23.92±1.28 years, weight 55.69±5.71 kg) were randomly divided into two experimental group (consumption of 250 ml barberry juice and exhausting activity) and control group (consumption of 250 ml placebo and exhausting activity). After the two-week supplementation, both groups performed exercise activity until they were of exhaustion on the treadmill. In this research, the nutritional value of barberry juice was extracted and the subjects' nutrition was analyzed. Blood samples were measured to measure the humoral immune variables in similar conditions in three stages of pre-test, after two weeks of supplementation and after the exhaustive test and using Independent T-test, ANOVA with repeated measure and Bonferron's post hoc test were analyzed at p≤0.05.
Results: The results showed that in the experimental group, the levels of immunoglobulin A (p=0.026), G (p=0.013) and M (p=0.017) after acute exhaustive activity were significantly higher than the control group, whereas in the experimental group cortisol values (p=0.018) were significantly lower than the control group.
Conclusion: It seems that consumption of barberry juice for two weeks with increased immune function reduces the effects of acute exhausting activity on the immune system in active girls.
Methods: In this clinical trial study, 20 healthy young girls (23.92±1.28 years, weight 55.69±5.71 kg) were randomly divided into two experimental group (consumption of 250 ml barberry juice and exhausting activity) and control group (consumption of 250 ml placebo and exhausting activity). After the two-week supplementation, both groups performed exercise activity until they were of exhaustion on the treadmill. In this research, the nutritional value of barberry juice was extracted and the subjects' nutrition was analyzed. Blood samples were measured to measure the humoral immune variables in similar conditions in three stages of pre-test, after two weeks of supplementation and after the exhaustive test and using Independent T-test, ANOVA with repeated measure and Bonferron's post hoc test were analyzed at p≤0.05.
Results: The results showed that in the experimental group, the levels of immunoglobulin A (p=0.026), G (p=0.013) and M (p=0.017) after acute exhaustive activity were significantly higher than the control group, whereas in the experimental group cortisol values (p=0.018) were significantly lower than the control group.
Conclusion: It seems that consumption of barberry juice for two weeks with increased immune function reduces the effects of acute exhausting activity on the immune system in active girls.
Type of Study: Research |
Subject:
Exercise Physiology
References
1. 1. Walsh NP. Recommendations to maintain immune health in athletes. Eur J Sport Sci; 2018. 18(6):820-31.
2. 2. Gleeson M. Immunological aspects of sport nutrition. Immunol Cell Biol; 2016.94(2):117.
3. 3. Campbell JP, Turner JE. Debunking the myth of exercise-induced immune suppression: Redefining the impact of exercise on immunological health across the lifespan. Front Immunol; 2018.9:648.
4. 4. Pearson MJ, Mungovan SF, Smart NA. Effect of aerobic and resistance training on inflammatory markers in heart failure patients: systematic review and meta-analysis. Heart Fail Rev; 2018.23(2):209-23.
5. 5. Gleeson M. Immune Function in sport and exercise. J Appl Physiol; 2007.103(2):693-9.
6. 6. Greenham G, Buckley JD, Garrett J, Eston R, Norton K. Biomarkers of physiological responses to periods of intensified, non-resistance-based exercise training in well-trained male athletes: A systematic review and meta-analysis. Sports Med; 2018.48(11):2517-48.
7. 7. Koch A. Immune response to exercise. Braz J Biomotricity; 2010.4(2):92-103.
8. 8. Simpson RJ, Kunz H, Agha N, Graff R. Exercise and the regulation of immune functions .Prog Mol Biol Transl Sci; 2015.135:355-80.
9. 9. Engels HJ, Kendall BJ, Fahlman MM, Gothe NP, Bourbeau KC. Salivary immunoglobulin A in healthy adolescent females: effects of maximal exercise, physical activity, body composition and diet. J Sports Med Phys Fit; 2018.58(7-8):1096-101.
10. 10. Metcalfe AJ, Koliamitra C, Javelle F, Bloch W, Zimmer P. Acute and chronic effects of exercise on the kynurenine pathway in humans - A brief review and future perspectives. Physiol Behav; 2018.194:583-7.
11. 11. Leicht CA, Goosey-Tolfrey VL, Bishop NC. Exercise intensity and its impact on relationships between salivary immunoglobulin A, saliva flow rate and plasma cortisol concentration. Eur J Appl Physiol; 2018.118(6):1179-87.
12. 12. Pedersen BK. Exercise induced immunomodulation, possible roles of neuroendocrine and metabolic factors. J Sport Med; 2007.18(1):27.
13. 13. Babaei P, Damirchi A, Assarzadeh M. The effect of a single maximal aerobic training on serum IgG and IgA. J Guilan Uni Med Sci; 2003.12(46) :1-6.
14. 14. Karampour S, Valizadeh R, Darakhshannezhad M, Hedayatmanesh Z. Comparison of immunoglobulins (IgA, IgG, IgM) and cortisol serum response following resistance and high intensity interval exercises. Jundishapur Sci Med J; 2017.16(1):13-23.
15. 15. Talebzadeghan M, Hashemi FS, Dehghan E.
16. Effect of 5 days vitamin C supplements on immunological stress caused by an aerobic exercise session in young women. Jundishapur Sci Med J; 2017.16(5):535-45.
17. 16. Shirvani H. Short-term effects of supplementation of coenzyme Q10 on humoral immune response to high intensity intermittent exercise in male soccer players. Koomesh; 2018.20(1):122-30.
18. 17. Imenshahidi M, Hosseinzadeh H. Berberis vulgaris and berberine: An update review. Phytother Res; 2016.30(11):1745-64.
19. 18. Rahimi-Madiseh M, Lorigoini Z, Zamani-Gharaghoshi H, Rafieian-Kopaei M. Berberis vulgaris: specifications and traditional uses. Iran J Basic Med Sci; 2017.20(5):569-87.
20. 19. Rad SZK, Rameshrad M, Hosseinzadeh H. Toxicology effects of Berberis vulgaris (barberry) and its active constituent, berberine: a review. Iran J Basic Med Sci; 2017.20(5):516-29.
21. 20. Kiasalari Z, Khalili M, Ahmadi P. Effect of alcoholic extract of Berberis vulgaris fruit on acute and chronic inflammation in male rats. J Babol Uni Med Sci; 2011.13(1):28-35.
22. 21. Hooshmand Moghadam B, Kordi M R, Mahdian S. The effect of barberry juice supplement on prostaglandin E2 level caused by intense aerobic activity in active young girls. J Birjand Univ Med Sci; 2017.24:1-9.
23. 22. Shirvani H, Ghahreman Tabrizi K, Sobhani V. Effects of high intensity intermittent exercise on serum immunoglobulin’s and complement system response in youth soccer players. J Birjand Univ Med Sci; 2013.20(3):233-43.
24. 23. Bruzda-Zwiech A, Konieczka M, Hilt A, Daszkowska M, Grzegorczyk J, Szczepanska J. Salivary cortisol, alpha-amylase and immunoglobulin a response to a morning session of basketball or volleyball training in boys aged 14-18 years. J Biol Regul Homeost Agents; 2017.31(1):105-10.
25. 24. Fathi M, Asadi Farsani M, Ali Adeli O. The effect of vitamin C intake after an exhaustive physical activity program of salivary immune factors. J Sabzevar Uni Med Sci; 2018.25(2):39-48.
26. 25. Papacosta E, Nassis GP, Gleeson M. Effects of acute post exercise chocolate milk consumption during intensive judo training on the recovery of salivary hormones, salivary SIgA, mood state, muscle soreness, and judo-related performance. Appl Physiol Nutr Metab; 2015.40(11):1116-22.
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
