Volume 25, Issue 7 (10-2018)                   RJMS 2018, 25(7): 62-69 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mohamadnezhad S, amirmozafari N, asmar M, nasrolahi M. Assessment of hepatitis B viruses serologic markers in special patients (thalassemia and dialysis) of Mazandaran province. RJMS 2018; 25 (7) :62-69
URL: http://rjms.iums.ac.ir/article-1-5105-en.html
Islamic Azad university, Sari, Iran , mohamadnejad_s@yahoo.com
Abstract:   (3072 Views)
Background: Nearly 300 million people worldwide are carriers of the Hepatitis B Virus (HBV). Thalassemia and dialysis patients are of the most important individuals at risk for the virus. Despite vaccination, antibody is reduced and there is a possibility of infection to HBV. This study, examines hepatitis B serologic markers among thalassemia and dialysis patients of Mazandaran province, Iran.
Methods: 94 patients were enrolled to our study. For all patients in the study, a questionnaire including demographic information, history of the vaccination for Hepatitis B, blood products transfusion and surgical history were completed. 5 ml of venous blood was taken from each student and serum was separated and stored in -20oC. For all samples, ELISA test was operated for Anti-HBs and Anti-HBc and HBsAg.
Results: Among 94 patients, 55 people (58.5%) were males and 39 people (41.5%) were females., 57 (60.6%) were dialysis patients and 37 (39.4%) were thalassemia patients, in which 4 people (7%) of dialysis patients and 8  (21.6%) of thalassemia patients were infected by HBV. 12 people (22.8%) were positive by the presence of HBsAg, 54 people (57.4%) were positive by the presence of Anti-HBs and 13 people (13.8%) were positive by the presence of Anti-HBc.
Conclusion: About 12.8% of patients were HBV positive and also 42.6% of them were sensitive to HBV. Therefore, their screening for HBV antibody is recommended before any blood products usage. Also, in order to provide adequate protection for the patients, the serologic studies is necessary.
 
Full-Text [PDF 712 kb]   (2595 Downloads)    
Type of Study: Research | Subject: Immunology

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Razi Journal of Medical Sciences

Designed & Developed by : Yektaweb