Volume 22, Issue 132 (6-2015)                   RJMS 2015, 22(132): 63-72 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Adult Still’s disease (ASD) . RJMS 2015; 22 (132) :63-72
URL: http://rjms.iums.ac.ir/article-1-3886-en.html
Abstract:   (9790 Views)

Adult Still's Disease (ASD) is an uncommon systemic inflammatory disorder of unknown etiology and pathogenesis characterized by high quotidian fever accompanied by systemic manifestations. There is no single diagnostic test for AOSD diagnosis is often clinical, and it is always necessary to exclude common disease mimics such as infections, malignancies and other rheumatic diseases. Ferritin and glycosylated ferritin are useful adjuncts to aid in the diagnosis of ASD. Treatment aims at both minimizing inflammation and halting disease progression. Non-steroidal anti-inflammatory drugs have limited efficacy so glucocorticoids in conjunction with disease-modifying antirheumatic drugs such as methotrexate are also used. Novel therapeutic approaches such as anti-tumor necrosis factor blockade, interleukin-1 (IL-1), interleukin-6 inhibitors and monoclonal antibodies are promising.

Full-Text [PDF 656 kb]   (21681 Downloads)    
Type of Study: review article | Subject: Rheumatology

Add your comments about this article : Your username or Email:
CAPTCHA

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Razi Journal of Medical Sciences

Designed & Developed by : Yektaweb