Razi Journal of Medical Sciences

 Streptococcus pneumonia is one of the most common pathogens in the humaun beings, specially in childhood. Knowing of it’s “Antibiotic resistance” is very important for antibiotic administration by medical persons. Between 1996-1997 nasopharyngeal culture has been done in 170 healthy child whom stayed in day care centers. Of 170, 51/8% (mean age=3.98years) were female and 48.2% (mean age=3.99years) were male. No different results were seen between sex. Group D Streptococcus(GDS) in 60% (mean age=4.069years), Group A Streptococcus(GAS) in 32.5% (mean age=4.098years), S.pneumonia in 2.5% (mean age=4.5years), H.inf in 0.6% (mean age=2years) of children were isolated. All of S.pneumonia were resistant to Penicillin and Ampicillin, but all of them were sensitive to Erythromycin, Co-trimoxazol, Chloramphenicol, Cephalothin, Ciprofloxacin and Vancomycin. Probably, S.pneumonia which colonized these child was not highly resistant to penicillin but was intermediate resistant.