For evaluating the effects of anesthesia on the incidence of postoperative nausea and vomiting, 61 patients candidated for total abdominal hysterectomy were selected and randomly entered in two groups, epidural (n=34) Vs. general anesthesia (n=27). Information about the complications was gathered after 24h by single blind manner. In general anesthesia group premedication drugs were fentanyl (1-2 µ g/kg) and Morphine (0.1mg/kg), Induction with thiopental (5mg/kg) and succinylcholine (1mg/kg), maintenance with Halothane (0.8-1.25%) and nitrous oxide (50%), pancrunium (0.1mg/kg) was used for muscle relaxation and at the end of the surgery patients were reversed by neostigmine and atropine.
Local anesthetics (lidocaine and bupivacaine) were used for epidural anesthesia. Post Operative Nausea and Vomiting (PONV) after general anesthesia occurred in 74% of cases and in 41% of epidural cases (P=0.020). Patients were divided in four groups according to the severity of PONV, then severity were compared between two Methods of anesthesia.
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