Razi Journal of Medical Sciences

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ABSTRACT Since anesthetic drugs have different unsuitable effects on fetus, local anesthesia is considered as the best method to prevent pain in the cesarean sections. Epidural usage of drugs is the choice of maintaining anesthesia. Epidural methadone and sufentanil both have been used separately in cesarean sections. This study was conducted to compare the anesthesia period and complications in cesarean section between the epidural methadone and sufentanil-administered women. Sixty cesarean candidate women were selected and divided in two groups. After local anesthesia induction, 0.15mg/kg methadone and 0.2 µg/kg sufentanil were administered for the first and second group, respectively. Anesthesia period and complications were determined using a previously validated questionnaire. Mean ages of study population were 33.4±7.8 and 34.3±6.4 years for methadone and sufentanil administered group, respectively. Mean anesthesia period for methadone group was significantly higher than sufentanil group(296±42min. Vs. 197±40min., p<0.05). The most prevalent complications were diaphoresis for the methadone and drowsiness and euphoria for the sufentail administered women. Anesthesia period in the epidural methadone administered women was significantly higher than sufentanil administered women. Considering the lower complication frequency, higher anesthesia period, lower costs and better access of methadone, respect to sufentanil, it seems that methadone is still more suitable to use in Iran.

Keywords: 1) Epidural anesthesia 2) Cesarean section 3) Sufentanil 4) Methadone

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