Volume 9, Issue 28 (6-2002)                   RJMS 2002, 9(28): 107-111 | Back to browse issues page

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Movassaghi G, Palideh H. COMPARISON BETWEEN ANTISHIVERING EFFECTS OF MEPERIDINE AND METHADON. RJMS 2002; 9 (28) :107-111
URL: http://rjms.iums.ac.ir/article-1-257-en.html
Abstract:   (12312 Views)
ABSTRACT Post anesthesia shivering induces a number of complications, which causes a variety of therapeutic approaches. Meperidine has been used as a drug of choice for the treatment of the complications in some patients while it is forbidden for some (e.g. those who use M.A.O inhibitors). In a randomized clinical trial 50 cases were selected and divided randomly in two groups, the first group received 25 mg meperidine (I.V) while the second group received methadone 2.5 mg/ 70kg (I.V) The anti- shivering effects were compared in the recovery room. The first group had a mean age of 33.76 years and second group 34.4 years. The mepridine group had a mean axillary temperature of 36.1 degrees ˚C while the second group had a mean of 36.08 degrees centigrade (P.value > 0.05) Also, the two group had shivering relief 84%, and respectively. The meperidine group had shivering relief after 30 seconds and the methadone group after 60 seconds, but these differences were not statistically significant (P.value > 0.05). The above results suggest similar anti- shivering effects for the two drugs and so, the two drugs could be used interchangeably.
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Type of Study: Research | Subject: Anesthesiology

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