Razi Journal of Medical Sciences

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Heavy smoker patients who are candidates for general anesthesia with tracheal intubation have hyperactive airways and are in risk of bronchospasm hypoxia after intubation and during operation. They also have repetitive coughs after extubation and recovery. The purpose of this study was to investigate the effects of inhaled Albuterol before induction of anesthesia on preventing bronchospasm, hypoxia and repetitive coughs in heavy smokers. In this study 60 heavy smoker patients, who didnot have infection, cough & productive sputum, dyspnea on daily activities and wheezing on physical exam, were randomly divided into two groups: study and control group. All of the patients were intubated after induction of GA with similar drugs. Patients in the study group received 2 puffs of salbutamol 20 minutes before induction of GA and before extubation. Bronchospasm during GA with the signs of hardening of the anesthesia bag, wheezing in hearing the chest, reduction of O2 saturation during and after the operation and the rate of coughing in recovery were also studied. In the control group 17 out of 30 patients and in the study group 9 out of 30 patients had one of those complications. Thus, it seems prophylactic salbutamol spray, which is a local B2 Agonist, reduces the incidence of bronchospasm and coughing in heavy smokers.

Keywords: Key Words: 1) Salbutamol spray 2) Bronchospasm 3) Heavy smoking 4) General anesthesia

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