Razi Journal of Medical Sciences

This is a retrospective study of 420 patients undergone thyroidectomy in Rahnemoon hospital during last 10 years.

The results are as follows: Thyroid malignancies and surgical procedures were three times more common in female than male. Mean age was 38.2 years for male and 35.1 for female. For both sex 4th decade of life was the most common age of disease. 22% of patients had Positive family history of thyroid disease, but this did not increase the incidence of thyroid malignancies. in thyroid malignancies 77% were female and 23 % male, with 4th of decade of life being the most common age of occurrence. all patients with malignant tumors and majority with benign lesions were euthyroid, so, abnormal thyroid function is indicator of benign lesions. solitary nodules were more common and occurred more in right Lobe than left. Incidence of malignancy in solitary nodules were 20% and in multinodular Lesions 13%.

In radioistope scan study, all malignant nodules and majority of solitary and multinodular goiters were cold nodules.

In surgery82% of all nodules were benign and 18% malignant. Most common benign lesions. were multinodular goiter and adenoma respetivelv and most common malignant lesions were papillary carcinoma, 66%, follicular ca.26%, medullary ca. 4.5%, sarcoma 1.5% and Hurthle cell ca, 1.5%.