Razi Journal of Medical Sciences

    Background: Oral reactive lesions are localized growth hyperplasia in oral mucosa caused by irritant factors. There is not enough information on relative prevalence of reactive lesions in Iranian population. The purpose of this study was to ascertain the prevalence of reactive lesions and its demographic data, clinical features, pathology and treatment procedure during a six year period.

Methods: In this retrospective study, all laboratory records of oral pathology were studied. Records with pathologic diagnosis of reactive lesions were chosen. Information from these records was recorded in tables. Reactive lesions were subdivided into soft (fibrous and hemorrhagic) and intra-osseous types. The frequency of information was analyzed Chi- Square test. SPSS V.17 was used for data analysis.

Results: From 443 oral lesions, 35.2% were reactive, 59% were seen in females and 56% were seen in patients aged less than 40 years. Meanwhile 95.5% of the reactive lesions were in soft tissue. Histopathologically, 59% were fibrous and 53.5% were pedunculated. The most common reactive hemorrhagical and fibrous lesions were pyogenic granuloma and irritation fibroma, respectively. Treatment was done with incisional biopsy and deletion of the etiologic factors.

Conclusion: It was suggested from the results of the study that reactive lesions have higher prevalence in the oral cavity. They are more common in females and under 40 years of age. The soft tissue reactive lesions are more common than the intra- osseous lesions which may be due to fact that they are more in contact with the localized irritative factors. The most common pathological lesions are fibrous with smooth surface.