Razi Journal of Medical Sciences

    Background & Aim: Stable and unstable angina and acute MI  happen due to atherosclerosis of coronary artery. The purpose of this study is comparing  the level of LP(a) with LDL-C, VLDL-C and HDL-C in patients with MI and unstable angina.

Patients and Method: This cross-sectional study was performed on patients suffering from MI or unstable angina who were admitted to 

Yahyanejad

Hospital in Babol between 2006 and 2007.The  patients were divided into MI group and unstable angina group based on the positive or negative result of troponin test. After  lipid profile test, information was recorded in a questionnaire. Then the data were analyzed by spss14, Chi-square and t-test. p<0.05 was considered significant.

Results: Among 218 patients in this study, 188 patients suffered from unstable angina and 30 patients suffered from MI.The mean of serum lipids was: LDL-C= 145.19±3.05,  VLDL-C= 30.89±1.48, Lp(a)= 65.15±5.31, TG= 154.41±7.41, CHOL= 221.41±3.68,and HDL-C= 44.48±0.69. Comparing the means of serum lipids in both groups of MI and unstable angina revealed a significant difference between levels of LDL-C, Lp(a), cholesterol ,and HDL-C (p<0.05), but in terms of VLDL-C and TG the difference  was not significant (p>0.05).

Conclusion: It can be concluded that a significant correlation exists between LDL-C,  cholesterol, low HDL and high Lp(a) in patients with unstable angina and AMI.