Volume 27, Issue 12 (2-2021)                   RJMS 2021, 27(12): 0-0 | Back to browse issues page

Research code: -
Ethics code: IR.IAU.M.REC.1396.186
Clinical trials code: -

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Amerian D, Nemti N A, Azarbayjani M A, BgherPoor T. Effect of aerobic training and octopamine on stress oxidative and PPARγ gene expression in brown adipose tissue of male rats fed with deep frying oil. RJMS. 2021; 27 (12)
URL: http://rjms.iums.ac.ir/article-1-6337-en.html
, Nnemati258@gmail.com
Abstract:   (115 Views)
Back ground and aim: Nowadays, role of physical activity and octopamine is known as an antioxidant. Therefore the purpose of present study was to determine the effect of aerobic training and octopamine on stress oxidative and PPARγ gene expression in brown adipose tissue of male rats fed with deep frying oil.
Methods: 30 male wistar rats were randomly divided into five groups (n=6): healthy control, DFO, aerobic training + DFO, octopamine + DFO and aerobic training + octopamine + DFO. Intraperitoneal injection of 10 ml/kg of octopamine and Gavage of deep frying oil were done five times a week and every day, respectively. The aerobic training protocol included 4 weeks, 5 sessions per week running on the treadmill for 20 min.
Gene expression of PPARγ was measured by Real time-PCR and ROS concentration was measured by ELISA test. T- independent test, Two-way ANOVA and Boneferoni post hoc test were used to analysis the data.
Results: The results showed that the aerobic training caused significant decrease in ROS and significant increase in gene expression of PPARγ (P <0.05) compared to DFO group. Interaction effect of aerobic training and octopamine caused the significant increase in ROS (P <0.05) and non significant difference in PPARγ gene expression (P >0.05) in comparison with DFO group.
Conclusion: It appears that interaction effect of aerobic training and octopamine can cause the improvement of stress oxidative of brown adipose tissue.
Key words: Aerobic training, Stress oxidative, Brown adipose tissue, Deep frying oil.
     
Type of Study: Research | Subject: Exercise Physiology

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