Volume 7, Number 20 (9-2000)                   RJMS 2000, 7(20): 122-125 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ghasemi S, Chehrei A, Sadeghi S, Ebrahimi A. EVALUATION OF DIAGNOSTIC VALUE OF GIEMSA STAINING AND RAPID UREASE TEST IN HELICOBACTER PYLORI. RJMS. 2000; 7 (20) :122-125
URL: http://rjms.iums.ac.ir/article-1-406-en.html

Abstract:   (8071 Views)

ABSTRACT

 Attention to high prevalence of inflammatory disease of upper gastrointestinal system and determination of Helicobacter pylori, “a great importance etiology of gastric disorders”, this study was performed for rapid diagnostic evaluation of Helicobacter pylori. This observational & cross-sectional study was performed in 100 cases who suffered from upper gastrointestinal symptoms. By an internist, at least two gastric biopsies with endoscope (From antrum region) were taken, one of the biopsies was used in H-E staining (reference for gold standard method) and its results compared with Giemsa stain result for determination of validity if Giemsa staining. Other biopsy was used in one minute rapid urease for rapid diagnosis in patient with H.Pylori infection and in statistical analysis of the results sensitivity, specificity, positive and negative predictive Values (PPV,NPV) and positive and negative likelihood ratio (PLR,NLR) were used. In Giemsa staining sensitivity was reported to be 95.9% and specificity was 44.4% and for rapid urease test sensitivity was 69.9% and specificity 85.2% PPV of Giemsa staining and rapid urease test were 82.3% and 92.7% respectively, and NPVof were 80% and 51% respectively. PLR in Giemsa staining and rapid urease test were 1.7 and 4.7 respectively and NLR were 0.09 and 0.35 respectively. Giemsa staining has a high sensitivity and its negative results is Valuable. Rapid Urease test has a high specificity, and its positive results are valuable but its negative results must be controlled with a sutiable reference test.

Full-Text [PDF 134 kb]   (3768 Downloads)    
Type of Study: Research | Subject: Infectious Disease

© 2015 All Rights Reserved | Razi Journal of Medical Sciences

Designed & Developed by : Yektaweb