Golnaz Ekhlasi, Farzad Shidfar, Shahram Agah, Shahin Merat, Khanom Agha Fatemeh Hosseini,
Volume 20, Issue 111 (9-2013)
Background: Regarding
the role of oxidative stress in the pathogenesis of non alcoholic fatty liver
disease and decrease of serum antioxidants concentration in these patients,
this study was conducted to investigate the effect of pomegranate juice intake
in weight loss diet of these patients.
Methods: In this
quasi-experimental trial (IRCT: 201102232709N17), 35 patients with the
diagnosis ofnon alcoholic fatty liver disease were selected. Initially, a
weight loss diet was designed for each participant. One glass of pomegranate
juice (250 mililiter) was substituted for required 2 servings of fruit for 3
months. Dietary intake, physical activity, anthropometric indices, and lipid
profile before and after the study were measured. Statistical analysis were carried out
using SPSS 19.0 by Wilcox on and paired t tests.
Results: From 35
participants, 33 (9 women and 24 men) completed the study. Pomegranate juice
intake along with weight loss diet resulted in significant decrease in liver
enzymes and increase in HDL-cholesterol (p= 0.01). Other lipid profile
variables had no significant changes.
Conclusions: According to the
results of this study, pomegranate juice intake along with weight loss diet can
be effective in improving clinical status of these patients and decreasing
cardio-vascular risk.
