Showing 42 results for Shams
H.a. Ebrahimi, S. Shams- Al - Dini,
Volume 2, Issue 0 (3-1996)
Abstract
The ataxia - telangiectasia or Louis - Bar syndrome is a rare hereditary disease. The inheritance pattern is autosomal recessive, locus gene has been mapped to the long arm of chromosome 11.
The onset of the disease coincides more or less with the acquisition of walking, which is awkward and unsteady. The characteristic telangiectatic lesions, are mainly subpapillary vascular plexuses of the bulbar conjunctivae and over the ears. In these cases ataxia at 1.5 and 2 years old appeared , but telangiectatic lesions appeared at 4 years.
There are high circulating levels of alpha - fetoprotein this is thought to be due to immaturity of the liver, and serum concentration of IgA and IgG are reduced. In these cases (one brother and sister), serum alpha fetoprotein significantly increased. In the sister, IgA is absent and in the brother level of IgA is decreased.
S.j. Sadjadi, M. Maleki, A. Shamszadeh,
Volume 2, Issue 0 (6-1995)
Abstract
Chest pain, especially in the left hemithorax, is a very common symptom, which often causes a patient to immediately seek medical advise, since it is often deemed to be related to cardiac diseeses.
Some chest pains can be easily diagnosed and treated when a careful tilstory is taken and physical examination performed. One of the causes of chest pain which is common among housewives and some men is "flower pot carrier's syndrome' of 'sadjadi-maleki syndrome" which is being reported heve for the first time in medical literature In this syndrome, the patient's complain of upper chest pain which is aggrevated by change in position and teepirstory movements. Physical examination reveals tender zones. these patients often have a histoty of cartying Flower pots, cylinders and other things with chest support.
In this syndrome, para clinic findings almost always are normal A ceretutnistory and physical examination can result in a definite diagnosis which will eliminate patient anxiety, save time and money wasted for unnecessary laboratory tests.
Mohammad Hossein Daei Parizi, Asadollah Shamsaldini,
Volume 5, Issue 1 (Winter 1999 1999)
Abstract
Hutchinson - Gilford syndrome or progeria is a rare genetic disease with failure to thrive, deficiency of pubertal development and dwarfism. These patients die of premature cardiovascular disturbances and other complications. Characteristic clinical features are finely thin skin, small chin, defect in skin adnexals, prominance scalp tends to be further enhanced by frontal and perietet bossing and by hypopfasia of the face. The cartilage was visible, the lips were thin and there was cyanotic overcast about the nose and mouth with premature aging, and let droping of the shoulders were the important findings in diagnosis ot Hutchinson Gilford syndrome in this case.
Sadollah Shamsaddini, Afshin Rezaei,
Volume 5, Issue 1 (Winter 1999 1999)
Abstract
Ort disease is a contagious viral infection, common in human and domestic animals.
Atter inoculation of virus to the skin a round target shape pustule appears. The virus is a DNA type that exists in perioral area of domestic animals such as sheep and goat. This is a descriptive study of 15012 patients older than 20 years old who were seen in dermatology center clinic in city of Kerman between the years of 1991-1996.
The incidence was 0.4%. Three forth of patients, 60 cases, were female and one forth were male. Most cases were in the age range 21-30 years old, and the rest in 51-60 years. The mean age was 40 years. Thumb and index finger were more involved than any other sites. Biopsy of skin lesions in 14 cases confirmed clinical diagnosis. Due to good prognosis and noninvasive nature of this condition no special treatmene is required, but occasionally in immune compromised patients application of 40% idoxouridine gel locally is helptut.
M. Farhadi, A. Tabatabai, A.r. Shamshiri, A. Maleki, F. Masjedian, M.r. Bojary Nassrabadi, P. Danesh,
Volume 7, Issue 19 (6-2000)
Abstract
Infection of middle ear and infection of sinuses are prevalent diseases in human populations which are caused by various etiological agents. To determine and compare the frequency of different virulent bacteria and fungi, the following study was conducted. 58 Patients with sinusitis and 52 with otitis media, which were candidates for surgery were studied irrespective of age and gender. Tissue samples or samples from local discharges obtained at the operation room were transfered to the laboratory in suitable transport media and were directly studied and subsequently cultured for the presence of aerobic and anaerobic bacteria and fungi. In the sinusitis patients the most prevalent virulent agents were bacteria (65.51%). The most prevalent aerobic bacteria isolated were S. aureus and S. epidermidis (62.92% in total) (P Considering the results of this comparative study, the frequency of aerobic bacteria was more than that of anaerobic bacteria in the patients of otitis media and the most prevalent aerobic bacteria are Pseudomonas and S. aureus specious (57.13% in toltal) (P |
A Tabatabai, M Poureslami, A.r Shamshiri, M Moshir,
Volume 8, Issue 26 (3-2002)
Abstract
The purpose of this investigation was to survey the epidemiological and other contributing factors on the establishment of fungal infections among patients visiting Hazrat Rasul-e Akram Hospital in Tehran. Five hundred patients suspected of having fungal skin infections were referred to the mycology lab and the specific fungal etiology was determined by both culture methods as well as slide culture observation.
We were able to isolate a total of 253 fungi which included 51.4% dermatophytes, 20.1% Erythrasma, 18.6% candidiasis, 8.3% pityriasis versicolor and 1.6% nail Aspergillus.
Dermatophytes consisted the most common etiologic agent ( Χ 2 =185, P<0.001), and the most common loci of infection in both sexes were groin(26.4% in male and 54.7% in females)(P<0.001, Χ 2 =29 and Χ 2 =178.2 respectively). Epidermophyton flucosum was the most common dermatophyte isolated ( Χ 2 =33.7, P<0.001) and its source was either from the pelvic region or the feet.
There was also a higher prevalence of fungal infections among those above 40 years of age (46.2%) ( Χ 2 =164, P<0.001).
M Moshir, S Arzpyma, M Shamsabadi, F Hoseini,
Volume 9, Issue 30 (12-2002)
Abstract
ABSTRACT
The purpose of this study was to compare the resistance of propiobacteriom acne (PA) and staphylococcus epidermis(SE) to antibiotics in patients that have been treated with antibiotics, With those cases without previous history of therapy as the control group. 60 patients were included in this study. At the time of sampling, all 30 cases of study group had been on therapy for a minimum of 4 months on oral tetracycline and topical clindamycin and erythromycin 30 patients were included in the control group without previous history of antibiotic therapy.
Mic (Minimum Inhibitory Concentration) was performed on PA or SE isolated from skin surface of these cases. Erythromycin resistant PA and SE isolated from antibiotic treated acne patients was 43.3% (P=0.024). Tetracycline resistant PA and SE isolated from study group was 40% (P<0.0001). Clindamycin resistant PA and SE isolated from study group was 43.3%(P=0.004).
Results of this study show that, incidence of resistance to antibiotics in patients undergoing antibiotic therapy for acne was higher than control group, and there is a correlation between the resistance of SE and PA and the former therapy for acne.
A Moradi Joshaghan, M Shams Shahrabadi,
Volume 10, Issue 35 (12-2003)
Abstract
This analytical observational and epidemiological study was done in order to evaluate the relative immunity to mumps in healthy and unvaccinated children in Karaj aged 4 to 7 years.Therefore, 194 serum samples were taken through no probability sampling and tested by hemagglutination inhibition test. For each of the samples dilution of 1/2 to 1/128 was tested using guinea pig red blood cells and mumps virus anti genes prepared in laboratory on cell culture. Then, obtained results were analyzed, as absolute and relative frequency in total, in girl and boy groups and in different age groups separately which revealed that 35% of total had no measurable antibody titer(below 1/2). Also 66% of total studied children were susceptible to mumps by considering the titer equal or greater than 1/8 as the protective titer. There was no significant difference between sex and susceptibility to the disease(P<0.05). According to the high percentage susceptibility of children to mumps, it is recommended to pay enough attention to immunization programms against this disease.
H Foruhesh Tehrani, M Shams Shahrabadi, H Raeessi Dehcordi, A.f Sarraf Nejad, K Jafari Nejad, M Talebi, M Moradi,
Volume 10, Issue 36 (12-2003)
Abstract
Campylobacteriosis is a zoonosis that occurs worldwide. Among 17 species in the genus of campylobacter, campylobacter fetus has special characteristics. In contrast to other species, which frequently cause diarrhea, C.fetus is primarily associated with extra intestinal infections such as septic abortion, septic arthritis, abscesses, meningitis, endocarditis, thrombophlebitis and salpingitis. Meninigitis in adults due to campylobacter fetus is a rare entity and only nine cases of it have been reported in the literature since 1983-2002. This is a case report of a 60-year-old woman who was hospitalized in Kasra Hospital due to having C.fetus.meningitis.
H Forouhesh Tehrani, M Shamsi Shahrabadi, M Moradi, M Talebi, A.r Abdolrasooli, M Al-E-Booyeh,
Volume 11, Issue 40 (9-2004)
Abstract
Corynebacterium urealyticum is a normal human skin flora. Mode of transmission is uncertain, but it can probably access to patients’ normally sterile sites endogenously. In spite of having low virulence, C. urealyticum has high resistance to antibiotics which allows survival in hospital setting. The incidence of infection caused by C. urealyticum is low. The most common infection is urinary tract infection, but infection in other sites has also been reported. In the present study out of 1338 positive samples, one case(0.074%) with corynebacterium urealyticum was isolated. The bacterium was sensitive only to vancomycine. Although C. urealyticum is not common, it is necessary to identify any diphtheroides micro-organisms from clinical site and to consider their clinical significance.
H Otukesh, R Hosseini Shams Abadi,
Volume 11, Issue 41 (9-2004)
Abstract
Nephrotic syndrome is an important disease in children and the diagnosis and treatment of its complications is important. Edema is one of these complications which is more common and severe in children and has different treatment in comparison with adults. Treatment of edema in children contains protocols that increase intravascular volume and decrease sodium reabsorption in all parts of nephron especially proximal tubule and aldostrone inhibitors, whereas sodium channel blockers in distal nephron(like amiloride) are used in adults. Albumin is an appropriate drug for the treatment of edema in children, although it has a few side effects such as expensiveness, intensifying interestitium nephritis and reducing furosmide effect. Therefore, nowadays, it has been tried to use drugs that have albumin advantages but no side effects(like manitol) for the treatment of edema. Thus, it was decided to use manitol and compare its effects with albumin on weight loss and reducing edema. The patients of the present study took albumin and manitol patient by patient. Weight loss(first and last weight) which was important for us was remarkable in both groups(Pv<0.001). There was no significant difference between these two groups of patients on manitol or albumin protocol regarding weight loss(Pv>0.005). Also, this weight difference did not have any relation with the amount of serum albumin in these two groups. Complications did not show any remarkable difference in both groups. Complications were evident in 16% of patients with manitol and 17% of other patients with albumin protocol. Complications in manitol protocol were hypokalemia and hypertension whereas they were hypertension and dehydration in albumin protocol. 15.8% of patients treated with manitol did not respond to this drug. This absence of response was seen in 30% of patients with albumin protocol. All the patients who were under manitol treatment and did not respond to it had MCD.
M Farhadi, A Daneshi, A Tabatabaii, M Sotoudeh, A.r Salek Moghaddam, A.r Shamshiri,
Volume 11, Issue 42 (12-2004)
Abstract
Breast cancer is the most frequent cancer among women. Approximately one third of all cancers in women is breast cancer which has a high mortality rate and is second only to lung cancer in cancer related deaths in women. Unfortunately, during the past 50 years, the prevalence of breast cancer has been raised probably due to life style changes. Recently, the prevalence of this cancer in different areas of world ranges between 8 to 23 in every one hundred women. The prevalence in Iran has not been established yet, but some unpublished data from three academic centers related to Mashhad University have indicated that the prevalence of breast cancer raised in women during reproductive age is different and has not been clearly identified. In addition, the risk factors in different countries are not the same and our country has its specific risk factors that should be identified. The main aim of this research was the assessment of certain breast cancer risk factors during reproductive age. This research was a descriptive-analytic and multi-variant study with two groups of case and control. The total number of participants in this research was 350 persons 170 of them were in case and 180 in control group. Interview forms were used for the assessment of the problem. Results indicated that variables such as age, race(heredity), geographic location of residence, occupation and its duration, history of marriage, the age at first pregnancy, mensturac regularity, nulliparity, history of preterm labor, history of infertility, medical and surgical history, cigarette smoke exposure and x-ray exposure are some significant risk factors associated with breast cancer among premenopausal women living in Mashhad.
A Tabatabaee, M Farhadi, A.r Shamshiri, S Nourbakhsh, Sh Mohammadi, R Falak,
Volume 13, Issue 50 (4-2006)
Abstract
Background & Aim: Nasal polyp is a common finding in patients referring to ENT specialists. Also, some specialists believe that there are patients with nasal polyp and some evidence of fungi. The present study was undertaken to describe coincidence of nasal polyp and fungi in patients referred to ENT ward of Rasoul-e-Akram Hospital in Tehran. Patients & Methods: 118 patients with nasal polyp(62.7% male and 37.3% female mean age 35 years, ranged 12-70) were investigated in a cross-sectional study. Results: 52.5% of the patients had high total serum IgE level. Direct examination and culture for fungi was positive in 32.5% and negative 36.4% of the patients. The most common isolated fungus was aspergillus(50.9%). Other fungi were candida(34.5%), penicillium (7.3%), alternaria (5.5%) and curvularia (1.8%). Mean age of patients with fungal infection was higher than patients with negative fungal culture result (40y vs. 35y P=0.06). Patients with high serum IgE level were more infected with fungi (49% vs. 14% P<0.001). Conclusion: Results showed that in nasal polyposis, a special attention must be paid to patients with high serum IgE and fungal infection.However, most of our patients had chronic sinusitis as well as polyps in their medical history which may affect our results. Therefore, further studies on patients suffering from nasal polyps and those cases with fungal sinusitis is suggested.
E Amin Tehran, A Tabatabaee, M Shekarabi, A.r Shamshiri, Sh Javadi Nia, N.s Alirezaee,
Volume 13, Issue 52 (9-2006)
Abstract
Background & Aim: Chronic infection of tonsils in childhood is a leading cause of adeno-tonsillectomy. A question has been asked for a long time to find out whether there is any risk of immune impairment after adenotonsillectomy. Therefore, the present study was undertaken to evaluate immunologic parameters in children before and after adenoidectomy. Patients & Methods: In this cohort study, 25 children(14 male and 11 female) candidate for adenotonsillectomy enrolled in Rasoul-e-Akram Hospital. Adequate blood samples were taken in 3 intervals(before surgery and 2 and 6 months after surgery) from patients to measure immunoglobulins IgA, IgM, IgG and IgG subclasses by nephlometry assay and count lymphocyte subsets(markers CD2, CD3, CD4, CD8, CD19, CD23 and CD56) by flowcytometry and ELISA methods. The data was analyzed by repeated measures (Anova and Bonferroni statistical tests). Results: Enrolled patients had median age of 8 years(range 3 to 16 years). IgM and IgG were equal in 3 intervals. IgA somewhat dropped after surgery(2 and 6 months after surgery vs. before surgery) and IgG subclasses(IgG1, IgG2, IgG3 and IgG4) had small rise after surgery. According to lymphocyte subsets CD4+ and CD23+ cells and CD4/CD8 ratio were constant through the 3 intervals. CD23+ and CD56+ cells had small drop in both intervals after surgery vs. before surgery, but these differences were not statistically significant(P>0.05). Mean CD8+ cells had significant changes during these intervals(P=0.02) especially between specimens before and 2 months after surgery(P=0.03). Same pattern was seen for CD19+ cells(P=0.012 and 0.01 respectively). Conclusion: Comparing immunoglobulins of the patients with normal ranges revealed that all antibody classes were highly above normal levels. IgM level in patients with 3 to 8 years remained above median normal level even 6 months after surgery. High antibody level in patients is related to recurrent antigenic stimulation of their immune system. Evaluation of the results in age groups also revealed that changes in immunoglobulins and T and B lymphocytes after adenoidectomy seems to be related to age. Results showed that immune system did not change in short term after adenoidectomy. However, more studies must be conducted to compare patients’ immune system with that of normal subjects in a long term evaluation.
M Farhadi, A Tabatabaee, M Shekarabi, A.r Shamshiri, M Kadivar, S Nourbakhsh,
Volume 13, Issue 52 (9-2006)
Abstract
Background & Aim: There are many suggestions for nasal polyp formation mechanism. The present study was carried out to evaluate T-cell infiltration in nasal mucosa and specific allergic reactions in context of probable irregular systemic immune responses in nasal polyp disease. Patients & Methods: 60 patients with nasal polyps who referred to ENT ward of Rasoul-e-Akram Hospital were studied in this cross-sectional study. Median age was 34 years(range 13 to 69 years) and 59.3% of patients were male. Blood and polyp specimen from each patient were sent to laboratory to measure serum IgE and specific IgE(by ELISA method) and count immune cells and subsets [by APAAP(Alkaline Phosphatase Anti Alkaline Phosphatase) and LSAB(Labeled Streptavidin Biotin) methods]. Results: 56.7% of patients had total serum IgE equal or more than 100IU/ml and others (43.3%) had total IgE lower than 100Iu/ml. 45% of the patients had at least one positive test from specific tests. Patients with positive specific IgE had more CD8+cells in comparison to others(P=0.04). They also had further serum IgE(P=0.001). Multivariable analysis showed that serum IgE, CD4/CD8 ratio and age were correlated with specific IgE result in patients with nasal polyp(R2=1 P<0.001). Conclusion: Immunopathologically IgE synthesis in allergic patients is biphasic. Total IgE increased as a response to primary immune system stimulation and then according to affinity maturation phenomenon, specific IgE increased. Therefore, patients with specific IgE have continuously high IgE level. In this study low CD4+cells may be due to low regulatory cells for Th1 lymphocytes and increased CD8+cells may be related to increased cells which secrete cytokines affecting Th1 or Th2 lymphocytes. To understand definite roles of immune cells in nasal polyp formation, more studies are needed to measure T lymphocyte subsets, Th1 and Th2 lymphocytes.
M Moshkgoo , M.a Taghipoor, A Shams Akhtari ,
Volume 13, Issue 53 (1-2007)
Abstract
Introduction: Hydatid disease remains a health problem for Mediterranean and Far Eastern countries such as Iran. Living in rural or suburban areas is an important risk factor for the disease. These cysts are usually located in the liver, lung, and brain and mediastinal hydatid cysts are rarely found. The objective of this investigation was to present a very rare and nearly unique case of mediastinal hydatid cyst with invasion to right brachiocephalic vein. The patient underwent an operation successfully. Case Report: A 37-year-old female who was complaining of exertional dyspnea underwent an operation with the diagnosis of mediastinal hydatid cyst. Surgical approach was midsternotomy and because of the above-mentioned invasion, brachiocephalic vein was injured during dissection. However, the vein was repaired with a pericardial patch during the second operation and resulted SVC(superior vena cava) syndrome was resolved too. No recurrence was seen in a period of 6 month follow-up. Conclusion: Primary hydatid cysts of the mediastinum are distinct clinical entities that should be considered in a patient with a mediastinal mass who lives in endemic regions and because of surrounding vital structures, the cyst should be removed surgically without delay.
N. Hooman, , S.j. Nasiri,, P. Alipour,, M. Mehrazma,, E. Talachian,, Kh. Mahlooji, , H. Otoukesh,, R. Hoseini Shamsabadi, , M. Feisal Naji Alanaghereh,,
Volume 14, Issue 57 (2-2008)
Abstract
Introduction: Pancreatitis is uncommon in children. The incidence is higher in chronic renal failure, hemodialysis, and chronic ambulatory peritoneal dialysis(CAPD) patients and accompanied with late complications including pancreatic necrosis, pseudocyst and abscess. Case Report: We report a 5 year old girl with end stage renal disease due to focal segmental glomerulosclerosis, being on CAPD for two years. She was admitted for intermittent severe epigastric pain of four months duration, hypotension, severe cachexia and cloudy drained dialysate with negative culture and mild increment serum amylase. On abdominal imaging a pancreatic cyst was reported which was an infected cyst on laparotomy. Despite drainage of suppurative fluid and antibiotic therapy, the patient expired with severe sepsis and multiorgan dysfunction two weeks after operation. Conclusion: The presence of poor weight gain, unexplained abdominal pain and cloudy drained dialysate in children on CAPD may suggest pancreatitis. Frequent evaluation of pancreatic function and sonography is recommended.
F. Moeini Alishah, , L. Hosseini Gohari,, B.sh. Shamsian,, L. Mosta'an, ,
Volume 15, Issue 0 (summer 2008)
Abstract
Background & Aim:
Since the mutant Hbs do not have any obvious electrical charge, globin chain separation is helpful for the diagnosis of
unknown Hbs. Therefore, the present study was carried out to detect alpha or beta chain variants by cation exchange
chromatography.
There are several point mutations in hemoglobin(Hb) genes which can cause hemoglobinopathy.Material and Method:
count(CBC), HbA2 and HbF percentages were determined by routine methods, and cellulose acetate and citrate agar
electrophoresis were performed on all the samples. For HbS confirmation, solubility test was performed and globin chains
were separated by carboxymethyl cellulose(CMC) chromatography in the presence of 8 M urea. SPSS version 14 was used
for statistical analysis.
In this descriptive study, 20 samples having abnormal Hb were selected. Complete blood cellResults:
agar electrophoresis. CMC chromatography revealed that three patients had abnormal beta chains, 15 had abnormal alpha
chains, and 2 remaining samples had abnormal alpha and beta chains.
According to the obtained results, all of the samples had an abnormal band on cellulose acetate and citrateConclusion:
helpful guideline for the selection of an appropriate gene for DNA sequencing. Moreover, this method is useful to screen the
cases for hemoglobinopathies and beta thalassemia coexistance, which can sometimes lead to severe clinical
manifestations.
Mutant alpha and beta chains can be detected by CMC chromatography and globin chain separation is a
A. Tabatabaee, M. Farhadi, S. Noorbaksh, M. Shekarabi, A.r. Shamshiri, N.s. Alirezaie, A. Vasheghani Farahani,
Volume 15, Issue 0 (Autumn,Winter 2009)
Abstract
Background and Aim: Inflammation is relatively a documented pathogenic cause of chronic rhinocynositis and nasal polyps, but the definite causes are still unknown. Among the infective causes, we decided to evaluate Mycoplasma and Chlamydia, the two major pathogens in respiratory tract diseases, as a potential etiologies in nasal polys.
Materials and Methods: In a descriptive-analytic cross-sectional study, 51 patients with nasal polyp and 19 healthy persons (with nasal fracture) who had referred to
Hazrat-e-Rasool
Akram
Hospital were enrolled in the study. Blood sample for ELISA and nasal polyp tissue (in control group a specimen from inferior nasal turbinate mucosa) for PCR tests were sent to the laboratory. Descriptive measures, Chi-square and Mac Nemar tests and Kappa agreement statistics were used for statistical analysis.
Results: Positive results for IgM, IgG and PCR for Chlamydia were 9.8%, 47.1% and 7.8% in patients and 0%, 47.4% and 0% in control group, respectively. The differences between the groups were not statistically significant. Similarly for Mycoplasma, the above mentioned results were 15.7%, 68.6% and 19.6% in patients and 15.8%, 47.4% and 0% in control group, respectively. According to IgG and PCR results, the differences between two groups seems to be significant (P =0.10 and 0.05 respectively).
Conclusion: Between the two evaluated bacteria in this study, mycoplasma may have significant correlation with nasal polyp formation. However further studies with larger sample size and considering more confounding factors are needed.
M. Moshkgoo, A. Shams Akhtary,
Volume 16, Issue 0 (spring 2009)
Abstract
Intoduction: Morgagni hernia is a herniation through the costosternal portion of diaphragm. Morgagni's defect usually occurs on the right side. Morgagni hernia is a rare hernia and occurs more commonly in adults.
Case report: A 4 years old child was referred to office for recurrent pneumonias. The patient was under treatment for his pneumonias since 2 years ago. On chest CT scan, transverse colonic segment and air fluid level was seen in the right hemi thorax.
Conclusion: With the diagnosis of Morgagni hernia, the patient was prepared for operation. Surgical approach was right thoracotomy. Herniated colon through morgagni defect was observed. The hernial sac was set free from a 2.5x2.5 cm defect in the anterior part of diaphragm. The colon was moved in to abdomen. The defect was repaired by 1-0 nylon sutures. After operation and often 1.5 years follow up, the patient is well with no complications.
