Showing 10 results for Oormazdi
M. Hoormazdi,
Volume 2, Issue 0 (3-1996)
Abstract
Multiple lymphomatous polyposis (M L P) is a rare type of gastrointestinal lymphoma presenting as multiple polyps involving large segments of the bowel. The lesions have been classified by immuno histochemical methods as • Mantle Zone Lymphoma' .
According to our knowledge, no case of M L P has been reported in Iran.
The 29 years old male who presented in this paper, is the youngest patient that has been reported in medical literature.
Hormozd Oormazdi, Seyed Kamran Soltani Arabshahi, Lame Akhlaghi, Ebrahim Mozafari,
Volume 6, Issue 2 (9-1999)
Abstract
Fascioliasis is a cosmopolitan parasitic disease common between human and herbivorous animals. Since the disease leads to significant liver damage, it should be diagnosed and treated more quickly and more accurately. The etiologic agent is Fasciola hepatica (and rarely Fasciola gigantica).
In Iran Fascioliasis is more prominent in the humid north provinces as compared to other areas. The disease initiates with ingestion of drinking water and raw vegetables (lettuce, watercress and ... ) that harbor metacercariae. Then, the larvae reside and mature in biliary ducts.
The most common symptoms are fever, right upper quadrant abdominal pain, eosinophilia, gastrointestinal disorders and allergic reactions.
Diagnosis is usually based on clinical symptoms and epidemiologic informations. It is confirmed by parasitologic and serologic methods. As parasitologic tests are only definitive in 30% of cases, and serologic methods are highly diagnostic and accurate, we used metacercaria precipitation test for early diagnosis of human fascioliasis for the first time in Iran. We used in vitro-bred metacercariae as major antigens. They were incubated with serum samples offasciola-infected patients and healthy individuals (control group). Different dilutions of 1/5 and 1/10 were used. Precipitation reactions were assessed after 6,24 and 48 hours. In this study, the sensitivity and specificity of the test at 1/5 dilution were higher than other dilutions and were 95% and 100% respectively. Due to the simplicity and the lack of heavy expenditure, and since the test helps early diagnosis of disease, we suggest that this be used at any part of the country. Due to unavailabillity of nitazoxanide, our patients, with positive metacercaria precipitation test, were treated with triclabendazole which was fUlly effective.
M. Shekarabi, H. Oormazdi, A. Ghamchili, M. Razavi,
Volume 8, Issue 25 (12-2001)
Abstract
Cryptosporidium parvum in humans,as a re-appeared and as one of the four most important ubiquitous enteric pathogen which can cause diarrhare with high level of mortality mainly in the munocompromised patients has stimulated research interested in the world. The quick and accurate laboratory diagnostic report of the pathogen are hlighly important in the prevention of the disease progress. Although kynion acid-fast(AF)staining procedure is accepted in the most clinical laboratories,a comparative study on the preferences of direct fluorescent (DF) antibody with staining techniques has undertaken in this recent work.During,months,beginning 1/5/1999,the stool samples of 340 apearantly healthy people,185 from patients under chemotherapy and 170 from children under 10 years with chronic diarrhae have been collected for our research studies.The obtained results are as following:1-The sensitivity,specificity and the simplicity of the direct fluorescent (DF) was 100% as compared with kynion acid-fast (AF) technique.2-With regard of minimum detection time unit,each (DF) slide needs one minute, while this time limit for each (AF) slide was 5 minutes.3-By compering the minimum diagnotic level(MDL) by expert technologists in two tecniques, it was 8 for (DF). In other words, at least 60000 oocysts/ml of liquid stools are needed until to be able to detect by (AF) while (MDL) for (DF) was 7500 oocysts/ml.4-By using a single blind test the experience quality of the technologist in two techniques of (DF) and (AF) were evaluated. This test was significantly prefered as compared with (AF) technique.5-In these studies we have found that 0.7% of healthy people ,0.5% of patients under chemotherapy and 4.1% of diarrhaetic children were infected with Cryptosporidium parvum
M Hoormazdi, B Bahramian,
Volume 10, Issue 35 (12-2003)
Abstract
In this case report, we present a 40-year-old man with the history of flank pain and weight loss in recent months. A left adrenal mass was the sonographic finding supported by CT-Scan. After light microscopic and immunohistochemistry examination and based on “ pheochromocytoma of adrenal gland scaled score(PASS)” the diagnosis was “Histologic malignant pheochromocytoma”.
M Hoormazdi, A Hassan Pour,
Volume 10, Issue 35 (12-2003)
Abstract
In this case report we present a 49 year old man with history of a mass in right upper quadrant and microscopic hematuria who referred to the hospital 2 months ago. In sonography, one cystic mass with multiple irregular septa in upper segment of right kidney and in CT scan, a multiloculated cystic mass in anterior of right kidney was reported. Under light microscopic examination the diagnosis was multilocular cystic renal cell carcinoma.
M Hoormazdi, A Hassanpour,
Volume 10, Issue 38 (3-2004)
Abstract
Mediastinal immature teratoma in autopsy of fetus is a very rare phenomena which has been reported so far just in two cases. The case of the present study was a 24-week dead female fetus delivered by C/S for intrauterine death. The mother was a 30-year-old lady (gravide 2, para 2) who referred to sonographist due to lack of fetus movement. In sonography intrauterine fetal death and hydrops fetalis was reported. There was no positive history of previous abortion or congenital anomalia in her first bady. Positive gross autopsy finding was pleuretic cyanotic edematous fetus and one solid mediastinal paracardiac mass. After classic cutting a mediastinal mass measured 3×2×2cm was seen. Hypoplasia of two lungs and heart due to compression effect of mass was evident. Microscopic examination of the mass revealed an immature teratoma.
B Nikmanesh, H Oormazdi, L Akhlaghi, M.t Haghi-Ashtiani, Z Ghalavand,
Volume 12, Issue 49 (3-2006)
Abstract
Background & Aim: Cyclospora cayetanensis is a new-emerging pathogenic protozoan parasite. It is a rare coccidian associated with gastrointestinal disorders. Cyclosporiasis occurs in persons of all age groups and either in immunocompetent or immunocompromised hosts. The most characteristic feature of this infection is a syndrome of acute or chronic diarrhea. This parasite is worldwide in distribution. Cyclospora can be transmitted by ingestion of water or food contaminated with oocysts. The present study was undertaken to assess the prevalence of cyclospora cayetanensis in children with diarrhea. Material & Method: During twelve months(from June 2002 to June 2003) 420 stool samples from children under 10 years of age with diarrhea, admitted into Tehran Children Medical Center were screened. To detect and identify the organism, direct smear, formalin-ether concentration, and staining(modified acid fast) techniques were used. Results: In this cross-sectional study, 31 out of 420 specimens(7.3%) showed parasite infection, but cyclospora cayetanensis was not detected in any of the stool samples. Conclusion: According to our study, it seems that cyclospora infection in Tehran is very rare and further studies with larger volume size of stool are necessary for cyclospora identification. We also suggest that medical practitioners and laboratories should be more aware of this infection and its diagnosis.
B Nikmanesh, H Oormazdi, L Akhlaghi, M.t Haghi Ashtiani, Z Ghalevand, Z Babaii,
Volume 14, Issue 54 (4-2007)
Abstract
Background & Aim: Nowadays one of the problems in developing countries is pediatric diseases and their mortalities. In this respect diarrhea plays a significant role. Cryptosporidium is recognized as an important widespread cause of severe and prolonged diarrhea mainly in immunocompromised or malnourished children, but there is no attention to identifying the parasite. The present study was designed and undertaken to assess the prevalence rate of agents causing diarrhea and determine the role of cryptosporidium and its relationship to some potential risk factors. Material & Method: In this cross-sectional study carried out during twelve months(from June 2002 to June 2003), stool samples from 420 children under 10 years of age with diarrhea who were admitted to Tehran Children Medical Center were screened. To identify parasites, direct smear, formalin-ether and modified acid fast staining techniques were applied. In addition, in order to distinguish pathogenic bacteria, differential media and polyvalent standard antisera were used. The obtained data was analyzed using descriptive and analytical statistics, i.e. Chi-square, t-test and Fisher exact test. Results: This study showed that after bacteria, parasites were important causes of diarrhea, and cryptosporidium(2.4%) following giardia(2.9%) was the second parasite isolated in children with diarrhea. Statistical analysis of our results indicated that existence of cryptosporidium was significantly related to the presence of mucus in stool(P<0.003), immune deficiency(P<0.01), and age(P<0.017). Conclusion: This study emphasized that laboratories include appropriate diagnostic techniques for cryptosporidium in the routine examination of watery or mucoid diarrheal stool specimens, particularly for immunosuppressed patients.
H. Oormazdi, , L. Akhlaghi,, E. Razmjoo,, M Beirom Vand, , Sh. Sarvi,, M. Tavalla,,
Volume 15, Issue 0 (6-2008)
Abstract
Background & Aim: Blastocystis hominis is an intestinal parasite in humans and animals. Despite extensive studies, pathogenic role of this organism is controversial. Prevalence rate of contamination with this organism varies from 1.5% to 10% in developed countries and reaches up to 50% in developing countries. The purpose of this study was to investigate total IgG, total IgA and IgG2 subclass in adults infected with Blastocystis hominis and compare them with healthy individuals. Patients and Method: In this cross-sectional case-control study, we selected 100 adults infected with Blastocystis hominis and 100 healthy subjects referred to health service sectors of Iran University of Medical Sciences and Milad Hospital. Serum immunoglobulin examinations were performed by means of nephelometry and Minineph human Ig kit made by the Binding Site Ltd., Birmingham, UK. Data analysis was done by SPSS version 12 and independent t-test. Results: According to the obtained results, there was no significant difference in the level of total IgA between the case and control groups(t=409, P=0.683), but the levels of total IgG and IgG2 subclass showed a significant difference between the case and control groups(IgG: t=2.83, P= 0.005 IgG2: t= 2.02, P= 0.002). Conclusion: The results showed that the immune system response to carbohydrate and glycogenic antigens of the central vacuole of this protozoon leads to an increase in the level of serum IgG especially IgG2 subclass.
Saba Arshi, Homan Zandavar, Hormozd Oormazdi, Lame Akhlaghi, Elham Razmjou, Ramtin Hadighi, Ahmad Reza Meamar,
Volume 19, Issue 102 (12-2012)
Abstract
Background : Toxocariasis is a common worldwide zoonotic parasite infection caused by the larvae of Toxocara catti and Toxocara canis. Allergic rhinitis is the most common chronic diseases in the upper respiratory tract. The main symptoms are sneezing, watery rhinorrhea, itching in the nose, eyes and palate. The purpose of this study was to investigate the association between toxocara seropositivity and allergic rhinitis compared with the control population.
Methods: This cross-sectional study was carried out from September 2009 to February 2011 on 93 patients with allergic rhinitis and 87 control subjects. Confirmation of the diagnosis of allergic rhinitis was defined by history and positive epicutaneous prick test. Control subjects were healthy based on history and no signs of allergic rhinitis and other allergic diseases were seen. Blood and fecal samples were taken from both groups. Sera were separated, labeled and stored at -20°C until used. Stool samples were examined by a wet mount and formalin-ethyl acetate concentration technique. The diagnosis of toxocariasis was established by IgG anti Toxocara and IgE total by ELISA method.
Results: In case group (allergic rhinitis) from 93 patients, 50 patients (53.8%) were males and 43 (46.2%) were female. In the control group of 87 individuals studied, 56 (64.4%) were males and 31 (35.6%) were female. In cases and controls, 5 (5.4%) and 3 (3.4%) of sera were positive for IgG Toxocara, respectively. There was no statistical difference in Toxocara seropositivity in both groups (p =0.39).
Conclusion: It seems to be in contrast to worms and allergies several factors, including phase worm infections (acute and chronic), parasite load, parasite species and resistance genes are involved and this require further studies in different ages and populations.
