Showing 3 results for Bahramian
M Hoormazdi, B Bahramian,
Volume 10, Issue 35 (12-2003)
Abstract
In this case report, we present a 40-year-old man with the history of flank pain and weight loss in recent months. A left adrenal mass was the sonographic finding supported by CT-Scan. After light microscopic and immunohistochemistry examination and based on “ pheochromocytoma of adrenal gland scaled score(PASS)” the diagnosis was “Histologic malignant pheochromocytoma”.
M Taklif, B Bahramian,
Volume 12, Issue 46 (9-2005)
Abstract
Fibro-Osseous lesions are numerous and heterogeneous group of tumors of the jaws which pose difficulties on classification, diagnosis and treatment. The present study was undertaken to evaluate fibrous dysplasia and the diagnostic value of histologic examination for its workup. Fifteen patients with cranio-facial bone lesion, who had previous pathologic diagnosis of fibrous dysplasia, were evaluated during 4 years (1998-2002) in Hazrat Fatemeh Hospital. Male-female ratio was 9/6 and patients’ range of age was between 16-38 years with mean age of 20 years. There were 12 patients with monostotic and 3 patients with multiple lesions of both jaws and skull. The maxilla bone was the most frequent site of the lesion. Clinicopathologic diagnostic correlation was 46.6%. There was one patient with malignant transformation of the lesion to osteogenic sarcoma. In microscopic view, 10 cases were classic fibrous dysplasia with evenly distributed islands of woven bone without osteoblastic rimming in a fibroblastic stroma, 5 cases showed variation in histologic pattern, 3 cases had focal or diffused osteoblastic rimming(ossifying fibroma) and 2 cases had rounded bodies regarded as a form of cementum both contained cellular stroma exhibiting mitotic activity named as cemento-ossifying fibroma. These two lesions showed more local aggressiveness and bone deformity in clinical and radiologic study than in classic fibrous dysplasia.
B Bahramian, A.r Sadeghipoor, H Darvish Ali,
Volume 12, Issue 48 (9-2005)
Abstract
Background & Aim: Therapeutic drug monitoring(TDM) is a very important function of a modern clinical laboratory. Chromatographic techniques have been the gold standard method for quantitative monitoring of drugs from the long time ago. Immunoassay methods are very useful today due to their ability to be installed on automation systems, their high speed and independence from expert personnel. The present study was undertaken to compare high performance liquid chromatography(HPLC) method with fluorescent polarization immunoassay(FPIA) for analysis of carbamazepine(CBZ) and phenobarbital (PHE) level in human blood. Patients & Methods: In this cross-sectional research 100 patients on PHE and 103 patients on CBZ regimen admitted to TDM center of Iran Reference Laboratories were sampled. Levels of drug in blood were measured. Data were recorded and then analysed by statistical tests of Pearson correlation coefficent(r), linear regression analysis and T-Test. Results: For PHE and CBZ, r was respectively 0.971 and 0.953, which indicated a good correlation between two methods. Linear analysis of regression and T-Test showed that data sets of FPIA method are a little higher than HPLC. Conclusion: Both HPLC and FPIA may be applied to determine PHE & CBZ in TDM. HPLC can be more useful in special cases who need high precision and TDM related research.
