Introduction: Tuberculosis is a common disease in developing countries. Extra pulmonary tuberculosis with involvement of pancreas is rare. Abdominal pain especially in epigastrium, fever, night sweat, jaundice and weight loss with pancreatic mass especially in young people is suggestive of pancreatic tuberculosis. Case Report: We report a 51 year old lady with fever, epigastric pain and weight loss from 2 months prior to admission. On sonography and abdominal CT scan a mass lesion was seen in head and body of pancreas with lymph node involvement. Workup with CT guided BX of pancreatic tissue and laparatomy was done. Pathologic report showed granolumatous lesion with caseous necrosis in pancreatic lesion and lymph nodes compatible with tuberculosis. Conclusion: Patient was put on 4 anti tuberculosis therapy response was good. Patient improved.
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