Volume 27, Issue 9 (11-2020)
RJMS 2020, 27(9): 11-20 |
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Research code: مقاله مستخرج از رساله دکتری است
Ethics code: IR.KUMS.REC.1398.691
Clinical trials code: مقاله مستخرج از رساله دکتری است
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aghaie S, behpor N, Hosseeinpoor Delavar S, safikhani H, jalilvand M. Effect of six weeks of increasing and complementary L-carnitine aerobic exercise on apline receptor for cardiac tissue and blood glucose in diabetic mice. RJMS 2020; 27 (9) :11-20
URL: http://rjms.iums.ac.ir/article-1-6284-en.html
URL: http://rjms.iums.ac.ir/article-1-6284-en.html
Islamic Azad University , n_bhpoor@yahoo.com
Abstract: (1770 Views)
Introduction: Consumption of non-enzymatic antioxidants in the form of dietary supplements can have a positive effect on reducing oxidative stress by hunting free radicals. The aim of Introduction: Consumption of non-enzymatic antioxidants in the form of dietary supplements can have a positive effect on reducing oxidative stress by hunting free radicals. The aim of this study was to explain the effect of 6 weeks of increasing and complementary L-carnitine aerobic exercise on the apline of the cardiac tissue and the blood glucose levels of diabetic mice.
Methods: In this experimental study, 40 males of Wistar male rats were randomly divided into five groups: healthy control, diabetic control, diabetes-L-carnitine, diabetes + aerobic exercise and diabetes + exercise + L-carnitine. After diabetic rats, they were given 100 mg of L-carnitine orally daily. The aerobic exercise program started 5 days a week, for six weeks, with a slope of zero degrees, a speed of 10 meters and a time of 10 minutes in the first week, and in the last week the slope reached 5 degrees, a speed of 20 meters and a time of 40 minutes.
Results: The results showed a significant increase in apline in diabetes groups + aerobic exercise and diabetes group + aerobic exercise + L-carnitine compared to the control group and placebo (p = 0.001). There was no significant difference between the two active research groups (p = 0.274). The results of the follow-up test showed a significant decrease in glucose in the active groups compared to the control and placebo groups (p = 0.001).Results: The results of the follow-up test showed a significant increase in apline receptor in diabetes groups + aerobic exercise and diabetes group + aerobic exercise + L-carnitine compared to the control group and placebo (p = 0.001). There was no significant difference between the two active research groups (p = 0.274). The results of the follow-up test showed a significant decrease in glucose in the active groups compared to the control and placebo groups (p = 0.001).
Conclusion: Aerobic exercise and L-carnitine consumption can increase the apline receptor of cardiac tissue and reduce glucose.
Methods: In this experimental study, 40 males of Wistar male rats were randomly divided into five groups: healthy control, diabetic control, diabetes-L-carnitine, diabetes + aerobic exercise and diabetes + exercise + L-carnitine. After diabetic rats, they were given 100 mg of L-carnitine orally daily. The aerobic exercise program started 5 days a week, for six weeks, with a slope of zero degrees, a speed of 10 meters and a time of 10 minutes in the first week, and in the last week the slope reached 5 degrees, a speed of 20 meters and a time of 40 minutes.
Results: The results showed a significant increase in apline in diabetes groups + aerobic exercise and diabetes group + aerobic exercise + L-carnitine compared to the control group and placebo (p = 0.001). There was no significant difference between the two active research groups (p = 0.274). The results of the follow-up test showed a significant decrease in glucose in the active groups compared to the control and placebo groups (p = 0.001).Results: The results of the follow-up test showed a significant increase in apline receptor in diabetes groups + aerobic exercise and diabetes group + aerobic exercise + L-carnitine compared to the control group and placebo (p = 0.001). There was no significant difference between the two active research groups (p = 0.274). The results of the follow-up test showed a significant decrease in glucose in the active groups compared to the control and placebo groups (p = 0.001).
Conclusion: Aerobic exercise and L-carnitine consumption can increase the apline receptor of cardiac tissue and reduce glucose.
Type of Study: Research |
Subject:
Exercise Physiology
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