Razi Journal of Medical Sciences

Background: Mucocutaneous lesions in the oral cavity have similar clinical features andhistopathological examination of the lesions is important for reaching a correct diagnosis.

The aim of this study was to assess the concordance between clinical and histopathological diagnoses in mucocutaneous lesions of the oral cavity during 10 years (2003-2012) in Babol Dental School.

Methods: In this retrospective study, records related to 150 patients with mucocutaneous lesions were analyzed in Babol Dental School from 2003 to 2012. Patient's data including age, gender, location of lesions, first, second and third clinical diagnosis that listed and histopathological diagnosis were recorded. Data analysis was done by SPSS software and Kappa and Mac Nemars tests.

Results: Present study showed that in 132 cases (88%) with oral mucocutaneous lesions, there was agreement between clinical and histopathological diagnoses. This concordance was 96.4% about lichen planus. Regardless of a case of lupus that clinically was not diagnosed, the highest percentage of inconcordance was found about lichenoid reaction in 53.3% of cases.

Conclusion: In order to reach a more accurate diagnosis of mucocutaneous lesions, clinical and histopathological features of lesions is needed.