Razi Journal of Medical Sciences

Background: Recent evidence suggests that adiponectin may play a role in bone metabolism. However, little is known about the effect of doing exercise in this relationship. The aim of this study was to determinate the relationship between the adiponectin levels and bone mineral density in 50-70 years old active and non-active men.

Methods: This is an analytical study. Thirty active and thirty non-active 50-70 years old men took part in this research. Bone mass density of femur and lumbar vertebras were measured by Dual-energy X-ray absorptiometry (DXA) and adiponectin was measured by ELISA method. Data were analyzed through independent t-test and Pearson correlation.

Results: Femur (p=0.02) and lumbar (p=0.03) bone mass density and adiponectin were significant higher in athlete group. There was negative significant relationship between adiponectin with bone mass density in active and non-active men.

Conclusion: Regular participating in exercise training can increase both bone mineral density and adiponectin in 50-70 years old men but it seems that the negative relation between bone mineral density and adiponectin is not affected by exercise.