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URL: http://rjms.iums.ac.ir/article-1-3411-en.html
, Abbas Rahimi Forushani , Siamak Heidarzadeh , Hossein Jabbari , Shahnam Sedigh Maroufi , Mohammad Kazem Sharifi Yazdi
Otitis media is one of the most common infectious diseases in children.
Approximately 85% of children will have otitis media at least once by the age of
3 months, and nearly 50% of children would have more than three times. The
objective of the this research was to detect Haemophilus
influenza, the most common cause of otitis media in children ,and to
determine the antibiotic susceptibility pattern of this organism.
Methods:
In this cross-sectional
study,a total of 102
specimens were collected during 6 months period from
patients with otitis media referred to Amir Alam Hospital in Tehran.Specimens were evaluated for Haemophilus influenzae by microscopic examination and culture. The
antibiotic susceptibility test was performed by disk diffusion method of
Kirby-Bauer and sensitivity
rate of tested antibiotics were assessed by evaluation diameter of the growth inhibitory
zone.
Results:
Out
of 102 tested specimens, 7 (6.9%) were identified
as Haemophilus influenzae .
The rate of sensitivity of isolated Haemophilus
influenzae to different antibiotics was
trimethoprim (100%), vancomycin (85%), streptomycin (57%), tetracycline (57%),
and doxycycline (56%),and the rate of resistance to gentamycin
(85%), carbenicillin (70%) and cefixime (70%), clindamycin (70%) amikacin
(57%) amoxicillin (57%).
Conclusion:
With respect to appearance
of new resistance species especially to clinidomycin , amikiacin and amoxicilin
it is recommended to perform antibiotic susceptibility tests before the
initiation of treatment.
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