Razi Journal of Medical Sciences

  Background: Metabolic Syndrome (MetS) is a physiological and biochemical disorder that are associated diabetes or elevated fasting blood sugar , obesity , triglyceride level and cholesterol disorders and hypertension.. The syndrome has been given several names such as Insulin resistance syndrome, Plurimetabolic syndrome, Reavens syndrome, Syndrome X and the deadly quartet. Some recent evidence have shown a significant correlation between MetS and lung disease especially Chronic Obstructive Pulmonary Disease (COPD). So we aimed to estimate frequency of MetS among a sample of Iranian patients of COPD (Chronic Obstructive Pulmonary Disease) and Chronic Bronchitis (CB).

  Methods : In this cross-sectional study, 204 COPD and CB Known cases evaluated as MetS development and demographic criteria, lipid profile, C reactive Protein (CRP) blood level, and smoking history and correlation of these criteria were assessed in these patients.

  Results: Frequency of MetS involvement among these subjects was approximately 48%. Age (p=0.003), abdominal obesity (p<0.001), high TG amount (p<0.001) and positive CRP (p=0.04) were correlated with MetS involvement.

  Conclusions: MetS was more frequent among COPD and CB patient.Age and underlying systematic inflammation Appears to be related to MetS.