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URL: http://rjms.iums.ac.ir/article-1-1904-en.html
Living organisms have multiple biological rhythms. Some of these rhythms are endogenous and some are under the influence of light and dati cydes during 24-hours. Nowadays periodic changes in melatonin secretion from pineal gland and changes in N-acetyl transferase (NAT) activity which influence the melatonin secretion rate has been acknowledged as a basic rhythm. In this study NAT activity in pineal gland of rats during the night in which the rate of melatonin synthesis reaches a maximum has been investigated. According to the techniques employed in the experiments it has become evident that NA T activity depends on the length of light exposure in the environment and, variations of environmental light, considerably changes pineal gland NAT activity by sympathetic innervation via norepinephrine release.
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