Razi Journal of Medical Sciences

Surface epithelial tumors constituted 65.7% of all the ovarian tumors. Brenner tumors are a type of surface epithelial tumors that constitute 1 % to 3% of all ovarian neoplasms. The average age of presentation of Brenner tumors is about age 50 and 7 I % of the patients are over 40. Most patients are asymptomatic but abnormal uterine bleeding is the most common presenting symptom. Associated endometrial changes ranging from glandular hyperplasia to invasive adenocarcinoma were reported. Microscopically, they consist of solid and cystic nests of epithelial cells resembling transitional epithelium (urotheIium) surrounded by an abundant stromal component of dense fibroblastic nature. Brenner tumors can be seen in association with mucinous cystadenoma and exceptionally, struma ovarii. They have also been found to coexist with transitional cell tumors of urinary bladder. We have found only one paper dealing with coexistence of Brenner tumor with adenocarcinoma of colon, has not been published previously.