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URL: http://rjms.iums.ac.ir/article-1-1492-en.html
Background: Vitiligo is a common skin disease in which depigmented macules appear on skin. The etiology of disease is unknown. There are many different treatment options available for vitiligo. The purpose of this study was to evaluate the efficacy of Hair follicle autograft in treatment of segmental vitiligo.
Methods: In this clinical trial study we transplanted pigmented hair follicles on segmental vitiligo patches that were unresponsive to other treatments and duration plus response of repigmentation was estimated. Ten patients who were suffering from segmental vitiligo were chosen for this study. One or two 5mm punch autografts were harvested from occipital area of the scalp, and trimmed and divided to micrograft (containing one hair follicle in each) and then inserted in to the depigmented areas. Data were analyzed with Chi-square test. SPSS V.14 was used.
Results: In all 10 patients, repigmentation spots of about 1-2mm, 2-4mm and 6-9mm in size appeared after 4, 8 and 12 weeks, respectively.
Conclusion: Follicular hair graft is one of the effective treatment methods for segmental vitiligo.
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