Razi Journal of Medical Sciences

  Introduction : Cerebral nocardiosis is a rare complication in patients who receive immunosuppressants, those with malignancy , AIDS, and transplant recipients.

  Case Report : Herein we present a case of Crohn’s disease who was being treated with prednisolone, salazine and azathioprine but suddenly faced a decrease in the level of consciousness and presented with the signs of focal neurologic deficit. Imaging studies revealed brain abscess and the patient underwent a surgery. Bacterial cultivation and histologic examination indicated cerebral nocardiosis and the patient was successfully treated with antibiotics.

  Conclusion :As far as we know, this was the first case of cerebral nocardiosis in a patient with Crohn’s disease who was receiving salazine, prednisolone and azathioprine. So far no similar case has been reported in English articles.