Volume 15 -                   RJMS 2008, 15 - : 163-168 | Back to browse issues page

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Moradi, S, Ghaffarpour, G. Thyroid Dysfunction and Thyroid Anti-Bodies in Iranian Patients with Vitiligo. RJMS. 2008; 15 :163-168
URL: http://rjms.iums.ac.ir/article-1-909-en.html
Abstract:   (6806 Views)

    Background & Aim: Vitiligo is a common skin disorder with unknown origin. An increased prevalence of autoimmune diseases, including thyroid diseases, has been described in patients with vitiligo. The aim of this study was to assess the prevalence of thyroid dysfunction and hypoparathyroidism in patients with vitiligo. Patients and Method: One hundred and nine patients(38 males & 71 females) with vitiligo were studied. Thyroid physical examination and thyroid function tests were done. Thyroid antibodies, calcium and phosphorus were measured. The collected data were analyzed by using SPSS version 11. Results: 30.1% of the patients had thyromegaly. Hypothyroidism was found in 16(15.7%) out of 109 cases. Two of them had clinical and 14 subclinical hypothyroidism. One patient had Graves disease. Anti-body positivity was the most common disorder(anti-TPO & anti-tg were positive in 36.7% & 32.1% respectively). No patient had hypoparathyroidism. Conclusion: According to our study, thyroid dysfunction especially hypothyroidism and thyroid antibodies increase in patients with vitiligo. Therefore, we recommend thyroid antibodies assessment and thyroid function evaluation in these patients.

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Type of Study: Research | Subject: Endocrinology & Metabolism

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