Research code: 1
Ethics code: IR.IUMS.FMD.REC.1400.652
Clinical trials code: 1

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School of Medicine, Aliasghar Children's Hospital, Iran University of Medical Sciences, Tehran, Iran , saberjavanmanesh@gmail.com
Abstract:   (14 Views)
Background: CT scan, as a simple and fast imaging tool, can accurately identify and evaluate lung lesions in children with COVID-19. Imaging patterns are still an important issue in the use of CT findings for clinical diagnosis of COVID-19. In the present study, our aim was to evaluate the CT scan findings in children infected with Covid-19 with positive and negative PCR referred to Ali Asghar Children's Hospital in 2021-2022.
Materials & methods: In this cross-sectional study children with covid-19 referred to Ali Asghar Children's Hospital in 2021-2022 included. Patients with Covid-19 were divided into two groups: (1) patients with positive PCR, (2) patients with negative PCR. All patients underwent CT during the first two days of admision, and then the required information was recorded in a checklist including clinical characteristics and imaging findings. The CT scans of the patients were reviewed by a pediatric radiologist, and finally, the CT findings were divided into 4 patterns based on RSNA Structured Reporting 3: Typical, Atypical, Indeterminate and Negative Category CTs). The data were analyzed using SPSS software version 23 and the significance level was considered < 0.05.
Results: A total of 59 subjects (40.4%) had lung involvement in their CT scan. (14 in the PCR-negative group and 45 in the PCR-positive group). Although lung involvement was higher in the PCR positive group than the negative group (42.5% vs. 35%), but this difference was not statistically significant. In our study, the predominant pattern among PCR positive and negative patients was Consolidation, Mixed and then GGO respectively. The dominant pattern in PCR negative cases was Consolidation, while GGO, Consolidation and Mixed patterns were seen almost equally in the PCR positive group and the difference between the two groups was close to significance. Although Halo and Round signs were more in the negative PCR group, there was no significant difference between these two groups in terms of Halo sign, Reverse Halo, Crazy Paving and Round signs between study groups. The rate of typical and intermediate involvement was equal (15.9%) and more than atypical (10.9%) in both negative and positive PCR groups, which was independent of the PCR result of the subjects. The typicality of lung involvement did not show a significant difference with the severity of the disease. Comparison of opacity distribution in lung CT scan showed that peripheral involvement in PCR positive cases is significantly more than PCR negative cases and this difference was statistically significant. Bilateral lung involvement was more in PCR positive cases, but the difference between the two groups was not statistically significant. The classification of lesions was almost the same between the two groups. Comparing the involvement of lung lobes showed no significant difference between the two PCR positive and negative groups.

Conclusion: our finding showed that peripheral involvements were more in the case of positive PCR than in negative PCR cases. The predominant pattern in PCR negative cases was Consolidation, while in the PCR positive group, GGO, Consolidation and Mixed patterns were seen almost equally and the difference between the two groups was close to significance
 
     
Type of Study: Research | Subject: Radiology

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