2024-03-29T02:58:03+04:30 http://rjms.iums.ac.ir/browse.php?mag_id=67&slc_lang=en&sid=1
67-1757 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 1999 6 3 Reduction of Complications Caused by Iodinated Intravascular Contrast Media: Ionic Versus Non-ionic Minoo Bozorgzadeh The risk of radiologic procedures is determined by different factors including contrast media, type of disease, procedure and skill of the physician. To reduce the contrast media-related risk, it is wise to use low osmolar contrast media (LOCM) in high-risk patients. When there is negligible cost difference between LOCM and other contrast media, it is wise to use LOCM for all patients. If an alternative procedure could avoid use of contrast media, it should be preferred (especially in high risk patients). Intravascular iodinated contrast media Ionic Contrast Media Non-ionic Contrast Media 1999 12 01 180 193 http://rjms.iums.ac.ir/article-1-1757-en.pdf
67-1758 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 1999 6 3 Estrogen Replasement Therapy in Postmenopausal Women and Breast Cancer Monireh Poorjavad Low levels of endogenous estrogens in postmenopausal women lead to several clinical problems. Some of these problems can be resolved by estrogen replacement therapy. The role of estrogen therapy in increasing the risk of breast cancer has not been well known yet. So, it was decided to study this controversial issue. In this study, 122 postmenopausal women, ranging in age from 46 to 61 years, were evaluated. They were divided into three groups. (1) 55 cases who received hormone replacement therapy (HRT) for 1-3 years (study group) (2) 55 individuals who did not receive HRT (control group) (3) 12 cases with known breast cancer. In el! of them, serum levels of estradiol was measured in the same laboratory, with the same method. The serum estrogen level was higher in the first group (75.62%, P < 0.001) as compared with the second. It was also shown that serum estrogen level in postmenopausal women with breast cancer is higher than first group (41.14%, P < 0.004). This level was also higher than second group (85.65%, P < 0.001). It can be concluded that serum estrogen level in postmenopausal women with breast cancer is higher than serum estrogen level in healthy postmenopausal women, whether they had received estrogen replacement therapy or not. Hormone replacement Therapy Estrogen Replacement Therapy Estrogen Estradiol Menopause Postmenopausal Period Climateric Breast Neoplasm 1999 12 01 194 200 http://rjms.iums.ac.ir/article-1-1758-en.pdf
67-1759 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 1999 6 3 Menkes Syndrome (A Case Report) Seyed Hossein Hassanpoor Avanji Mohammad Ghofrani We described the first case of Menkes syndrome in an Iranian infant in Tehran. He was admitted for control of seizure and assessment of developmental delay in Mofid' s Children Hospital in .January 1997. Clinical symptomatologies a/l favored the diagnosis of Menkes disease which was confirmed by low serum copper and ceruloplasmin levels. Menkes Disease Copper Deficiency Copper Metabolism Degenerative Brain Diseases Ceruloplasmin 1999 12 01 201 204 http://rjms.iums.ac.ir/article-1-1759-en.pdf
67-1760 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 1999 6 3 Prevention of Preterm Delivery: Nifedipine or Magnesium Sulfate Ladan Haghighi In this study a comparison was made between the efficacy and side effects of nifedipine and magnesium sulfate in inhibition of preterm labor. 74 cases in preterm labor were randomized to either oral nifedipine (n = 34) or intravenous magnesium sulfate (n = 40). All cases were primigravid with singleton pregnancies and gestational ages of 23-36 weeks. Both groups were similar in terms of age, gestational age and cervical dilatation. There was no significant difference between effectiveness of magnesium sulfate (70%) and nifedipine (76.5%) in arresting labor and delaying delivery more than 48 hours. Also the difference between maternal complications was not significant in these groups. But, the time needed to stop preterm labor was shorter with nifedipine (2.98 ± 3.02 hours) than magnesium sulfate (4.8 ± 4.23 hours) (P = 0.04). So, as the administration of nifedipine is easier and its effect appears faster than magnesium sulfate and the difference between efficacy . and side effects of these drugs is not significant, it can be concluded that nifedipine is an appropriate alternative to the magnesium sulfate in meneqement of preterm labor. Pregnancy Complication of Pregnancy Preterm Labor Preterm Delivery Nifedipine Magnesium Sulfate 1999 12 01 205 209 http://rjms.iums.ac.ir/article-1-1760-en.pdf
67-1761 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 1999 6 3 Study of Association of HLA Schizophernia in Iranian Patients of Shahid Esmaeili Hospital Alireza Salek Moghaddam Hamid Mostafavi Malihe Kamgooyan Mohsen Imani Mehdi Shekarabi Schizophrenia is the worst illness that affects human mentality and is considered as a chronic mental disorder. According to the report of WHO, the overall prevalence rate of schizophrenia is 0.7-1% in any L·: population. Due to this high rate of prevalence, many studies have been conducted in this field. As incidence and severity of this illness are influenced by genetics, as an intervening factor, studies which are conducted to clear this issue seem necessary. Despite many reports of association of HLA antigens and schizophrenia in other countries, nothing was known in Iran. So, we decided to conduct this study. In this study, the frequencies of 52 antigens of class I and II were determined in 45 schizophrenic patients and were compared with those of control group. Of these 45 patients, 20 cases were female, with a mean age of 29 years and 25 cases were male, with a mean age of 35 years. All these patients were physically healthy. To determine the frequencies of the aforementioned antigens, microlymphocytotoxicity method was employed. The results show that the difference of frequencies of A9, AW19, 85,815,851, 8w6, CW3, DR5, DR11 and DQ1antigens is significant (P < 0.05) between case and control groups. Of these antigens, the relative risk (RR) was higher than 1 in Bw6 and Cw3 and lower than 1 in the others. It can be concluded that the antigens 8w6 (RR=4.6 and etiologic factor [EF]= 0.72) and Cw3 (RR=2.67 and EF=0.13) are positively associated with schizophrenia. Other may have a protective role. Schizophernia Major Histocopatibility HLA Antigens Medical Genetics Immunological Diseases Microlymphocytotoxicity reactions Susceptibility 1999 12 01 210 222 http://rjms.iums.ac.ir/article-1-1761-en.pdf
67-1762 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 1999 6 3 Leiomyosarcoma of Abdominal Cavity ( A Case Report) Roya Setareshenas Farid Karami A 50 years old woman came to Firuzabadi General Hospital with both flanks pain. By ultrasonography and abdominal or scanning, a mass was found near the right ovary. With the possible diagnosis of ovarian tumor, the patient underwent hysterosalpingo-oophorectomy. In the operative field, the mass was found in the mesentery of small intestine and was removed. It was an encapsulated, solid and firm mass with a diameter of 15 centimeters. microscopic study showed a low-grade malignant spindle cell tumor. The findings of immunohistochemical staining were compatible with leiomyosarcoma. Cancers Smooth Muscle Tumors Abdominal Cavity Tumors Leiomyosarcoma 1999 12 01 223 228 http://rjms.iums.ac.ir/article-1-1762-en.pdf
67-1763 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 1999 6 3 Serum Level of Circulating SCC Tumor Marker in Head and Neck Tumor Seyed Fatollah Moosavi Bafrooei Pirooz Salehian Dardashti Babak Behnam For determining the sensitMty and specificity of serum level of circulating sec tumor marker, for diagnosis of head and neck primary tumors and metastatic types of see and non-See tumors, the present study was conducted. 89 patients with head and neck tumors (thyroid tumors were excluded) were studied during a one year period. When the questionnaires were completed and radiologic measures and clinical tests were performed, the patients underwent the clinical and pathologic diagnoses and received medical therapy. All the regular and special methods of histopathology were applied for final diagnosis. Of 89 cases, 50 (56.2%) proved to have squamous cell carcinoma and 39 (43.8%) proved to have non-See tumors with 21 different pathologic types. To measure the above mentioned marker, blood samples were obtained from the cases and were tested by immunologic, biochemical and enzymatic mothods. Then the results were compared with results of pathologic diagnosis. The final result shows that the level of see tumor marker increases significantly (P < 0.0001) in sec of head and neck. Moreover, in patients with malignant tumors of head and neck, the level of this tumor marker is higher (P < 0.05) than patients with benign tumors of head and neck. It should be noted that, according to pathological diagnosis, 73% of head and neck tumors are malignant and 23% are benign. Circulating Tumor Marker Tumor Marker SCC-Ag Head and Neck Neoplasms 1999 12 01 229 238 http://rjms.iums.ac.ir/article-1-1763-en.pdf
67-1764 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 1999 6 3 Feeding Patterns in The First Two Years of Life West of Tehran Shahandokht Najm Abadi Ahmad Kafashi In this descriptive cross-sectional survery, 820 children less than 2 years old were studied. The study was conducted in west of Tehran where the public health is supervised by Iran University of Medical Sciences and Health Services. Cases were selected by random stratified cluster sampling. It was shown that only 29.7% of infants were breast-fed within the first hour of life. 94% of children received colostrum. The rate of exclusive breast-feeding in first 6 months of life was 59.6%. Also, the feeding pattern of 15.5% of children was predominant breast-feeding in the first 6 months of life. Breast-feeding was continued in more than 59% of children older than 12 months. The rate of breast-feeding declined predominantly in the second year of life, especially in 16-18 months of age. In 87.3% of children, supplementary foods were introduced at 4-6 months of age. The most common age of introducing supplementary foods was end of 5th month and beginning of 6th month. Nutrition Infant Feeding Breast- Feeding Exclusive Breast- Feeding Predominant Breast- Feeding Supplementary Feeding 1999 12 01 239 245 http://rjms.iums.ac.ir/article-1-1764-en.pdf
67-1765 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 1999 6 3 Comparison of Argyrophilic Nucleolar Organizer Regions in Normal Throid, Nodular Goiter and Throid Neoplasms Forough Hashemi Parvaneh Nasseroleslami Argyrophilic nucleolar organizer regions (AgNORs) are loops of ribosomal DNA in the nucleolus and are associated with acidic proteins that have a high affinity for silver. In this study, the mean AgNOR counts were evaluated in specimens. Seventy three specimens were examined, including 16 normal thyroids, 19 nodular goiters, 21 follicular adenomas and 17 thyroid carcinomas (11 papillary, 4 follicular carcinomas, and 2 medullary carcinomas). The specimens were stained, using modified AgNOR staining method. It has been shown that mean AgNOR count increases from normal thyroid (1.45 ± 0.21) to papillary carcinoma, nodular goiter (1.60 ± 0.29), thyroid carcinoma (total) (1.78 ± 0.38), follicular adenoma (1.79 ± 0.42), follicular carcinoma (2.10 ± 0.12) and medullary carcinoma (2.22 ± 0.32) (mean ± SD). But, statistical analysis of the above findings, using unpaired Student's t test showed that mean AgNOR counts in adenoma and carcinoma are significantly higher than normal thyroid (P< 0.05), but the difference between other groups was not significant. There was also significant overlap in mean AgNOR counts of these groups. It can be concluded from these results that the mean AgNOR counts may have no diagnostic value in differentiating benign and malignant lesions of thyroid on paraffin embedded sections. Thyroid Diseases Argyrophilic Nucleolar Organizer Regions AgNOR Diagnosis Laboratory Diagnosis 1999 12 01 246 252 http://rjms.iums.ac.ir/article-1-1765-en.pdf