2024-03-29T17:08:44+04:30 http://rjms.iums.ac.ir/browse.php?mag_id=63&slc_lang=en&sid=1
63-1678 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 SCLERODERMA-LIKE SYNDROM (WERNER’S SYNDROM) “A RARE CASE REPORT” M.B. Owlia A. Haghighi A. Javadzadeh Scleroderma-like syndromes are a group of disorders that mimic systemic sclerosis. Werner’s syndrome is a genetically inherited syndrome that can be misdiagnosed as systemic scleroderomia. The syndrome is charachterized by sclerosis or stiffening of the skin, progeris, bilatera l juvenile cataract, endocrinopathies, premature coronary artery disease, alopecia, nail plate changes, hyperpigmentation and susceptibility to malignant neoplasms. We describe a case of Werner’s syndrome who presented with chronic leg ulcer and was misdiagnosed as systemic sclerosis for many years. We stopped unnecessary treatments and chronic leg ulcer was biopsied to rule out of skin cancer and managed locally by antibiotics and daily care. 1) Werner’s syndrome 2) Progeria 3) Scleroderma-like syndrom 4) Systemic sclerosis 2003 3 01 637 642 http://rjms.iums.ac.ir/article-1-1678-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 COMPARATIVE ANALYSIS OF 5 DIFFERENT FUNCTIONAL TESTS IN ACL DEFICIENT AND HEALTHY SUBJECTS E. Ebrahimi takamejani A Shademan M.J. Shaterzadeh M.R. Keyhani The purpose of this nonexperimental study was to compare 5 functional preformance tests between ACL deficients & healthy males. These tests includes co-contraction semicircular, carioca, shuttle run, timed hop and cross over hop. Functional tests are used to assess readiness of the subject to progress to another level of rehabilitation, to return to athletic practice, or to discharge. Selection of the appropriate battery of tests is important to maximize information about the patient’s functional capacities. Inthis study 16 males with ACL injury(group1) & 32 healthy males(group2) participated. Descriptive statistics for each parameter and variables measured in this research was done. Also two sample analysis for each functional tests between groups was done. Results: 1. Significant difference wasn’t seen in co-contraction semicircular test between two groups(P>0.05). 2. Significant difference was seen for carioca, shuttle run, timed hop and cross over hop tests between two groups(P<0.05). Above functional tests are objective measurment methods of functional instability which can be performed in a clinical setting, do not involve expensive equipment and require minimal time. 1) Anterior Cruciate Ligament 2) Functional test 3) Rehabilitation 2003 3 01 643 648 http://rjms.iums.ac.ir/article-1-1679-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 COMPARISON OF DERMATOLOGIC PATIENTS QUALITY OF LIFE WITH H. Ansarin A. Kabir A.A. Mirishekarab Quality of life is a composite measure of physical, mental and social wellbeing as preceived by each individual or by group of individuals that is to say happiness, satisfaction and gratification as it is experienced in such life concerns as health, marriage, self-esteem, creativity, belongingness, and trust in others. Dermatologic discorders have a major impact on patients’ psychosocial state, and every day activities. Comparing quality of life in patients with and without skin disease can be a determinor of life situation in dermatologic patients and show different aspects that affect in their life. It can be a mean to give better therapeutic services, promotion of life level give advise preventive cares to them. It’s an observational-comparative study applied on 100 patients suffering from psoriasis, acne, eczema, pigmentation disorders (melasma, vitiligo), alopecia, and 100 healthy people selected from the relatives who accompanied patients attending the dermatology clinics, as control group. The control group had a similar mean of age and sex distribution. Finally, the quality of life which include the activities and psychosocial compliants by a likert questionair consist of 15 questions with validity equal to 0.4 and reliability coeficient (cronbach’s alpha) equal to 0.81, compared between the patients and the controls. In analysis t test, one way ANOVA and nonparametric equivalents of them and univariate general linear model (for deletion the effect of confounding variables) were applied. The quality of life in patients was worse than controls. (P<0.009) In the psychosocial part, the patients’ quality of life was worse than the controls, too(P<0.009). There was a positive correlation between the quality of life by age (P=0.01, r=0.125) and income (P=0.022, eta=0.22) in all cases & controls. The worse quality of life in the patients with acne and pigmentation disorders may be induced by the visibility of lesions and being younger rather than the others. A special notice to the psychic part of dermatologic disorders is crucial and a psychiatrist can help the dermatologic patients, even they have not the psychologic compliants. About the patients who don’t make a good response to current dermatologic therapies, we can consult a psychiatrist. Also comparison of the Quality of life -before and after of treatment- can be used for the evaluation of the efficacy of treatment. 1) Quality of life 2) Dermatologic disorders 3) Activity 4) Psychosocial problems 2003 3 01 649 658 http://rjms.iums.ac.ir/article-1-1680-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 INVESTIGATION OF THE EFFECT OF ULTRAVIOLET WAVES CAUSED BY INDUSTRIAL WELDING ELECTRODES TO INDUCE SKIN CANCER IN BALB/C MICE M. Bahar K. Parivar P.H.S. Javadi All of the ultraviolet wave radiations, including UVA can alter the immune system of the skin. Scale cells cancer of the skin and malignant melanoma are caused by UVA radiation, but researchers insist more on the carcinogenetic effect of UVB spectrum. UVB spectrum is produced from the sun, sodium vapor lamp and electric and welding radiation of metal electrodes. In this study, the effect of UV produced from the metal electrodes on the skin and ear of one month and two months years old Blab/c mice during 25, 50 and 100 hours exposure time have been investigated. The results show that UV irradiation from welding decrease the number of hair follicles. Also increase in epidermis thickness and external and internal epidermis of ear is significant in one month and two months years old mice. The other skin layers in the same ages show alternate changes in different exposure times. It may be concluded that the incerase in epidermis thickness under UV radiation caused by welding can induce skin cancer and decrease of hair follicles may increse pathological risk of the skin. 1) Cancer 2) Skin 3) Mouse 4) UV Radiation 5) Bioeffect 2003 3 01 659 668 http://rjms.iums.ac.ir/article-1-1681-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 PRIMARY OVARIAN LYMPHOMA. REPORT OF A CASE FROM FIROOZGAR HOSPITAL M.H. Badakhsh F. Hashemi S.M. Razavi On this study a case of primary ovarian lymphoma (pol) in a 23 years old girl is reported that one year after ablative surgery and adjuvant chemotherapy is alive and disease free. Ovarian lymphoma is a disease reportedly poor prognosis but most cases of ovarian lymphoma actualy are involvement the ovary in diffuse lymphoma, and true pol is very rare. Little previously reported cases is not sufficient for recognition of clinicopathological features of this rare entity, however pol usually carries a fovarable prognosis and radical surgery in not essential. 1) Malignant lymphoma 2) Ovarian tumor 3) Cancer 2003 3 01 669 674 http://rjms.iums.ac.ir/article-1-1682-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 COMPARISON OF DIURETIC SONOGRAPHY AND DIURETIC RENAL SCAN IN DISTINCTION OF OBSTRUCTIVE AND NONOBSTRACTIVE HYDRONEPHROSIS B. Piranviseh M. NaroieNejad B. Rezaeimehr Sonography is a valid paraclinic test for evaluation of urinary tract obstruction it can evaluate urinary tract only from static point of view. We want to evaluate the dynamism of urinary flow by inducing diuresis. In our study 32 patients were selected and diuretic renal scan were perfromed in all of the patients. Diameter of the renal pelvis were measured before and after diuresis.(by real time sonography). On the basis of previous studies, obstruction were defined as increasing of renal pelvis diameter greater than seven milimeters. Then results of these metods compared. In the initial sonographic evaluation 50.97% of kidneys were hydronephrotic, therefor were considered obstructive. After diuresis 26.6% of kidneys were considered obstructive. On the basis of diuretic renal scan 23.4% of kidneys were obstructive. In two patients with renal malrotation, results of diuretic sonography and diuretic renal scan were not compatible. We concluded that diuretic sonography in comparison with diuretic renal scan, with 93.3% sensitivity and 94.85% specificity, can differentiate obstructive from nonobstructive hydronephrosis. This method can be used in initial evaluation of suspected urinary tract obstruction and in follow up of patients after treatment. 1) Sonography 2) Urinary tract obstruction 3) Diuresis 2003 3 01 675 680 http://rjms.iums.ac.ir/article-1-1683-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 INVESTIGATION OF THE POSSIBLE EFFECT OF CHRONIC OCCUPATIONAL EXPOSURE TO X-RAYS ON THE AMOUNT OF TRACE ELEMENTS ZINE AND COPPER IN THE BLOOD OF X-RAY TECHNICIANS M. Haidar Barghi B. Bolouri F. Osati Ashtiani H. Goorabi There are a few studiees on low dose effect of ionizing radiation on radiation workers. Of these, the x-ray personnel who are exposed to very low dose, long term radiation because of the profession, become important in this regard. This study was aimed to compare the two very important trace elements, zinc and copper, in the blood of 44 hospital x-ray technicians (XRTs) who have received less than 0.05mSv of radiation bimonthly with non radiation workers of the same centers. Blood samples of the candidates were tsken for comparison of zinc and copper contents, employing Acid Digestion technique by Atomic Absorption Spectrometry (AAS). The average levels of zinc in XRTs and control group were 6.409 and 6.589 mg/L respectively. The values for copper were 1.006 and 1.044 mg/L respectively. The results indicate although there were lower concentrations of both elements in XRTs than the controls, using t-test the difference was not statistically significant(P>0.05). However comparing corresponding female and male subjects of each group, the decrease of copper in female XRTs (1.062 mg/L) compared to control females (1.143mg/L) was significant (P<0.01). Hence the possible effectiveness of chronic occupational exposure on the blood tract elements is supported. 1) X-ray technicians 2) Low dose radition 3) Zinc and copper tract element 4) Atomic Absorption spectrometry 2003 3 01 681 686 http://rjms.iums.ac.ir/article-1-1684-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 A NEONATAL LUPUS SYNDROM “CASE REPORT” N. khosravi P. Mohagheghi Neonatal lupus syndrome is a rare disease. The manifestations of this disease in neonatal period include congenital heart block, cutaneous leasions, liver disease, thrombocytopenia, Neutropenia, pulmonary and nurologic derangements. Most of the clinical manifestations ofter disappear spontaneously. Although congenital heart block is usually permanent, and often require pacemakers. Congenital heart block is dangerous and life theratening. It may cause fetal death but more commonly results in neonatal cardiac morbidity, or neonatal death. A typical antenatal presentation is a fixed fetal heart rate of 50 to 60 beats per minute. Neonatal lupus syndrome is due to maternal IgG antibodies, directed against the ribonuclear protein of cardiac antigens. Which can be detected in 20-25% of serum samples. At the present time there is no intrauterine successful treatment. Although in utero pacemake placement has been attemped, no successful cases have been reported. The incidence of congenital heart block is reported between 15 to 30% and 50-70% of them need pacemaker placement. In this article, a neonatal lupus syndrome with congenital heart block is presented. This is the first child of a 25 years old mother, who is a known case of SLE pericardial effusion and cardiomegaly were reported is hersonographies and the fetus shoued fixed bradycardia, A term 3450 gram neonate was born with fixed heart rate of 70 perminute. He showed grade II congenital heart block and was referred to another hospital for pacemaker placment but he died because of complete heart block which did not respond to CPR attempts. 1) Lupus 2) Infant 3) Congenital heart block 2003 3 01 687 690 http://rjms.iums.ac.ir/article-1-1685-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 EVALUATION OF DISABILITY AND DEPRESSION IN PATIENT WITH OSTEOARTHRITIS IN KERMAN M.R. Shakibi M.A. Ramezani J. Atapour G.A. Rajabizadeh Osteoarthritis (OA) is the most common joint disease in the world and it’s an important cause of longterm health problems and the most frequency reported reason for disability in the papulation. To determine the relationship between disability and depression cross sectioanl study in kerman was design in OA patients. OA was diagnosed by criteria of American college of Rheumatology, disability measured with Clin-HAQ and depression measured with Beck inventory questionnaire. Of 200 OA patients 83.5% were female, meanage of this population was 54.1±11.3 years, 6 pearson had treuma, 21 diabetes mellitus and 52 had hypertension, mean of MBI was 26.6±5.5 kg/m2 and depression were 16.6±9.3 and disability was 0.97±0.4 wald foeward stepwise logestic regression models had been shown that depression and female sex were significants predictors for disability and disability was significants predictors for depression. OA Occurred in elderly people Age > 50 and is more frequent in women than men. Depression and disability have relationship together and which of them has a risk factor for other in patients with OA. 1) Osteoarthritis 2) Disability 3) depression 2003 3 01 691 698 http://rjms.iums.ac.ir/article-1-1686-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 COMPARATIVE STUDY OF BIODEX DYNAMIC BALANCE AND LIMITS OF STABILITY TEST IN NORMAL SUBJECT AND PATIENT WITH CHRANIC LOWBACK PAIN M. Salavati H. Bagheri E. Ebrahimi Takamjani B. Mobini   The purpose of this nonexperimental case-control study was to compare the postural control abilities in normal subjects (n=25) and patients with chronic low back pain (n=25), selected by nonprobability convenient sampling. The Biodex balance system was used to implement dynamic test in four positions including double-leg eyes-open (DEO), double-leg eyes-closed (DEC), single-leg eyes-open (SEO), single-leg eyes-closed (SEC) and dynamic limits-of-stability (LOS) test. Overall, anteroposterior and mediolateral stability indices as wall as the time percent of zone A (<5 ˚ inclination) were measured in dynamic balance tests while the completation time and overall directional control were measured in LOS test. Independent-t test ( α =0.05) were used to compare dependent variables between two groups. All dependent variables showed statistically significant difference (P<0.01) between the two groups except for AP stability index in DEO position. The most obvious differences were seen with eye closure and in ML indices. Based on these results, chronic low back pain patients had abnormalities in balance control both during body maintainance and weight shift. The patients had visual dependency and lateral instability. Balance problems, motor control abnormalities, proprioceptive deficits and muscular stabilizing systems of lumbopelvic region must be considered for successful evaluation and management in patients with chronic low back pain. 1) Chronic low back pain 2) Balance 3) Motor Control 4) Force Plate 2003 3 01 699 708 http://rjms.iums.ac.ir/article-1-1687-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 MODIFIED BANKART PROCEDURE, USING MODIFIED ANCHOR SCREW: SHORT TERM STUDY M. Ziaee H.R. Yazdi 45 patients (40 male & 5 female) with recurrent anterior shoulder instability were operated from 1993 to 2001. The mean age was 27 years (18-46) and 95% were right handed and 5% left handed. Instability was on right side in 54.4% left side in 38.6% and bilateral in 6.9%. 15 pt’s were operated with classic Rowe procedure and 30 pt’s with using modified anchor screw, and follow up period was 37.6 mounths (12-110), Bankart lesion was found in 100% of cases. Subscapularis muscle lesion, Interval lesion and capsular laxity in 9.3%, 14.5% and 47.6% respectively. Glenoid fracture and loose body in 2.9 and 29% respectively. In 75% of pt’s Hill-Sachs lesion was found that was moderate to sever type in 88%. At follow up study, First group (with no modified screw), there was no apprehension sign in 53.3% and redislocation in one patient and full range of motion in all cases. In secound group (with screw), no apprehension in 79% and no redislocation was found and range of motion was full in 93%. The first group has little or no limitation at their function in 90% and secound group in 96%. According to rowe scores, results were 53.3% excellent, 26.6% good 13.3% fair and poor in one case for first group and 69% excellent, 15.5% good and 15.5% fair without poor result in sceound group. In conclusion, using modified anchor screw for bankart procedure is easy to do, needs less instruments, with low surgical trauma, shortoperation time, and low complication rate and over all good results. 1) Shoulder instability 2) Bankart procedure 3) Anchor screw 2003 3 01 709 722 http://rjms.iums.ac.ir/article-1-1688-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 EFFECT OF ENDOTRACHEAL INTUBATION AND SUCTION AT BIRTH FOR PREVENTING MORBIDITY AND MORTALITY IN MECONIUM ASPIRATION SYNDROM A. Arab Mohamad Hoseini N. Khosravi Meconium-stained amniotic fluid (MSAF) occurs in approximately 5-20% of live births that meconium aspiration syndrome occurs in approximately 4-5% of these neonates after birth with breathing meconium goes to the small bronchial tree and clinical manifestation such as respiratory distress and tachypena, is present. Thease patients have high mortality and morbidity. For this reason, we studied two groups of infants with meconium stained fluid and compaired mortality and morbidity in two groups. One group was intubated and suction immediately after, and other group was not intubated. In this study, that was prospective and analytical cross-sectional, infants who were delivered with meconium-stained amniotic fluid (MSAF) throught a 3 years period (1996-1999) AkbarAbadi Hospital were studied. In this period 33037 infants were delivered and meconium-stained amniotic fluid (MSAF) occurred in 3254 (9.85%) of this live births. In 217 instance (6.67%) amniotic fluid was thick, in 188 (86.64%) of this infants the trachea was immediately. After birth intubated and suctioned. But unfortunately in 29 infants (13.36%). The trachea was not immediately after birth intubated and suctioned. In the intubated group complications included: Sepsis 17.55% (25 patients), pneumothorax 13.82% (26 patients), respiratory distress syndrome (RDS) 15.42% (29 patients), peresistent fetal circulation (PFC) 3.19% (6 patient). In 29 infants (13.36%) that we couldn’t intubated and suctioned, complications included: sepsis 10.34% (3 infants), pneumothorax 37.93% (11 infants), RDS 17.24% (5 infants), PFC 6.9% (2 infants). In all in intubated group complications were in 45.74% (86 infants) that 6.38% (12 infants) of this were died. In unintubated group, complications were seen in 72.41% (21 infants), that 13.79% (4 infants) were died. In this study intubation and suction immediately after birth in thick meconium-stained amniotic fluid decreased meconium Aspiration syndrome but increased it’s morbidity. 1) Meconium Aspiration 2) Infant 3) Pneumotorax 4) PFC(Persistent Fetal Circulation) 2003 3 01 723 728 http://rjms.iums.ac.ir/article-1-1689-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 COMPARISON OF THE THERAPUTIC AND SIDE EFFECT BETWEEN CIMETIDINE AND METOCLOPRAMIDE IN THE NON ULCER DYSPEPSIA: A RANDOMIZED CLINICAL TRIAL A.H. Faghihi S.H. Samedanifard Y. Najian  Nonulcer dyspepsia (NUD) is one of the most common gastrointestinal disorders. The causes of dyspepsia include gastric acid oversecretion, gastrointestinal dysmotility, Helicobacter pylori infection, some diets and psychologic factors. Many drugs such as H2-blockers and Prokinetics are perscribed in NUD. We designed a randomized clinical trial in Shohadaye Haftome Tir Hospital, Tehran, Iran at 2000 to compare efficacy of cimetidine and Metoclopromide in NUD and their side effects. This study were designed as a double blind randomized clinical trial on 101 patients suffering from NUD in shohadaye Haftome Tir Hospital, Tehran, Iran at 2000. The patients with NUD were selected. The inclusion criteria were having at least one of the symptoms epigastric pain, bloating, heart burn (pyrosis), vomiting nausia, regurgitation, fullness and halitosis for 3 months. Then patients were examined physically and their ESR, CBC, FBS, BUN, Cr, Ca, P, Na, K, SGOT, SGPT, AlkPh, T3RIA, T4RIA, TSH, Stoole Exam(3 times) Abdominal Sonography and Electrocardiography were checked to rule out cardiac, pulmonary, hepatic, panceratic disease and electrolyte disorders. Endoscopy was done for each patient by gastroentrologist to rule out any lesion in esophagus, stomach and deodenum. Finally the patients who had not used any drugs since 2 weeks before and hadn’t had history of psycologic disorders, were selected. After illustration and taking agreement of this patients, they were devided into two groups randomly: group of Cimetidine (50 persons) and group of metoclopramide (51 patients). The drugs were similar in shape and size and color. Cimetidine were from chemidaru company 200mg 4 times daily and metoclopramide from hakim company 10mg 4 times daily. These drugs were administred while 2 weeks in two groups simultaneusly. Complete treatment was defined getting rid of all their symptoms. Partial treatment was defined reminding symptoms to less than 50% and finally no treatment was defined reminding more than 50% of their symptoms. Group of cimetidine included 26 males and 24 females while metoclopromide group 25 males and 26 females. In the cimetidine group, the mean of age was 28.4 with standard deviation of 7.84 years. In the other one, the mean of age was 33.02 years with standard deviation of 10.77 years. There were not any significant differences in age and sex between these two groups. In cimetidine group 14 persons (28%) were completely treated, 23(46%) partially treated and 13 (26%) were not treated while in the metoclopromide group 19 persons (37.3%) were completely treated, 20(39.2) partially treated and 12(23.5%) were not treated. There were not any significant differences in treatment of NUD between these two groups. Also there were not any significant differences in side effects of these drugs except drowsiness that was significantly more in metoclopromide group (P-value=0.01). In the metoclopromide group, Anxiety in females were significantly more than males(P-value=0.02). There were many risk factors in NUD, also there were many drugs with different mechanism for NUD. Therefore we need more studies to know whichone of these drugs are better and have less side effects. 1) Non Ulcer Dyspepsia 2) Cimetidine 3) Metoclopromide 2003 3 01 729 740 http://rjms.iums.ac.ir/article-1-1690-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 AN INVESTIGATION OF METHODOLOGICAL FORMAT PREPARATION OF THESE BY MEDICAL STUDENTS OF IRAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, 1999 M.M. Mirsamadi A. Chehrei A.H. Bagherzadeh   University is a suitable place for research because of enough facilities and active students. Each student should has enough knowledge in research field before his or her graduation. Submission of an appreciate thesis could be a beginning for advanced research, therefore we evaluated the methodological structure of submitted theses by medical students in Iran university of medical sciences in first academic term of 1999. In this cross-sectional study we studied all theses belong to medical students graduated in first term of 1999. Different parts of thesis (e.g. title, abstract, introduction, method and material, results, discussion and references) were evaluated for methodological structure and analyzed by statistical tests. In this study “title” gained highest score (14.97 out of 15) and then “results” gained 19.31 out of 25, “introduction” gained 11.66 out of 15, “method and material” gained 75.8 out of 100, “discussion” gained 13.1 out of 20, and “references” gained 7.83 out of 15. Also, “new ldeas” gained 34.3 out of 40 (range: 23.38-35.22), “regularity” gained 16.88 out of 20 (range: 16.14-17.63), “Suggestions” gained 24.58 out of 45 (range: 21.78-27.4). Mean score for “methodological structure” was 224.8 out of 305 (range: 217.46-222.14).   Although this study is about evaluation of methodological structure of theses, it would be necessary for more research about superiority and quality of theses, and statistical errors of them. We suggest that all these must be evaluate carefully not only for methodological structure but also for all scientific features for up-grading quality of theses. 1) Thesis 2) Medical student 3) Methodological structure 2003 3 01 741 750 http://rjms.iums.ac.ir/article-1-1691-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 ASSESSMENT OF STATE OF FUNCTION & ANATOMICAL FORM OF THYROID IN PATIENTS WITH GOITR M. Mashayekhi H. Alizadeh F. Davoudi Goiter (diffused or focal enlargement of thyroid), is one of the most frequent complaints referred to endocrinologists. Goiter is evaluated for thyroid function & anatomical from of the gland. Understanding distribution of patients among different groups, & their signs & symptoms will help to choose a better diagnostic & therapeutic approach. Possible differences of patients characteristics in different geographic regions, & lack of sources related to our country were causes to design the study bellow. A retrospective, observational, cross-sectional study was conducted to assess the function & anatomical form of thyroid in patients with goiter. 1000 patients were selected through systematic randomization from those categorized as goiter in institute of endocrinology & Metabolism. All data about age, sex, state of thyroid function & anatomical forms, in addition to sign & symptoms were collected & analyzed with SPSS 9.50 (α-0.05, POWER=90%, CI=0.95). Mean, SD, Chi ^ 2 & One Way ANOVA were used in statistical analysis. Total mean age was 26.95±0.72. 88.9% were females & 11.1% were males 78.21% of patients were Euthyroids, 20.68 were hyperthyroids & 1.1% hypothyroids. There was a significant difference in mean of age among different groups according to TFT (P=0.0000). 60.74% of patients presented with simple goiter, 11.84 with multinodular nontoxic goiter, 13.95% with diffused toxic goiter, 3.71% with toxic multinodular goiter, 5,62% with a cold nodule & 2.51% with a hot nodule. There was a significant difference in mean of age among different groups according to goiter form (p=0.0000). 91.01% of euthyroid patients, 81.95% hyperthyroids & 100% of hypothyroids were female & the other members of each group were males. 80.2% of females were euthyroids, 18.55% hyperthyroids & 1.2% hypothyroids. 65.2% of males were euthyroids & 34.5% were hyperthyroids. There was a significant difference for sex among different groups according to TFT (p=0.002) & goiter form (p=0.0000). There was no significant difference for staging of goiter among different groups according to TFT (p=0.153) & goiter form (p=0.212) (power=90%). Palpitation was the most frequent sign among euthyroids (25.16%) & hyperthyroids (59.2%). Weakness was the most frequent sign among hypothyroids. There was a significant difference for sign & symptoms among different groups according to TFT (p=p.pppp). The majority of patients were euthyroids then hyperthyroids & hypothyroids. Simple diffused goiter, then diffused toxic goiter & non-toxic multinodular goiter were the most frequent forms of goiter. Low mean of age & higher prevalence of heperthyroidism compared to hypothyroidism is due to endemic Iodine deficiency. Higher hyperthyroidism ratio in men compared to women & the higher prevalence of multinoduar goiters need more studies to find the underling cause. Since euthyroidism is the most goiters need more studies to find the underling cause. Since euthyroidism is the most prevalent state of functions & there is a significant difference for sign & symptoms among different groups it is recommended to pay more attentions to clinical signs of patients before requesting TFTs. So that waste of money & laboratory sources is avoided. 1) Goiter 2) State of thyroid function 3) Thyroid function test 2003 3 01 751 758 http://rjms.iums.ac.ir/article-1-1692-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 COMPARISON OF DIETARY PATTERN IN HOUSEHOLD IN WEST OF TEHRAN AND DIETARY PATTERN RECOMMENDED IN NUTRITIONAL GUIDS SH. Najmabadi M. Nojomi In this descriptive cross-sectional survey, main perpose was evaluated the food pattern of house holds in west of Tehran. 1149 household resident in west area of Tehran where the public health is supervised by iran University of Medcial Sciences and Health services Were selected by random stratified cluster sampling. Data collection was done by interview method using as frequency questionaire. The results show: inadequency consumption in milk and dairy food group 7.6% households had no consumption of this mainfood group in daily foodpattern. Inadequency consumption in vegetable and fruite group was shown that 43.4% houseolds had no daily consumption in veg. Food group and 25.6% households had no daily consumption of fruite group. As recommended nutritional Guids to consumpt vegtables 3-5 serving daily and 2-4 serving fruite group daily. Statistical analysis show mean consumption of food groups in different area was significantly diffrence. 1) Dietary pattern 2) Main food groups 3) Foods from the major 4) Recommended dietary Guid 2003 3 01 759 766 http://rjms.iums.ac.ir/article-1-1693-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 ASSESSMENT OF DIETARY INTAKE BASED ON THE FOOD GUIDE PYRAMID IN A GROUP OF TEHRANIAN ADULTS P. Mirmiran F. Mohammadi F. Baygi N. Kalantary F. Azizi For individuals of a population, taking into account varying individual factors such as age, sex, growth stages of puberty, and significant durations such as pregnancy and lactation accompanied by physiologic changes, the importance of appropriate dietary intakes must be emphasized. The food guide pyramid is one of the best daily dietary guidelines that can be used to achieve this purpose. Since dietary assessments have generally focused on evaluating the adequacy of nutrient intakes and little attention has been paid to following the recommendations of the food guide pyramid, this study was performed to assess existing problems in current food habits and to offer solutions required in inhabitants of district 13 of Tehran.This is a cross-sectional study conducted within the framework of the national tehran lipid and glucose study (TLGS) on 920 individuals (472 women and 448 men) aged 10 years and over, who were randomly selected from the TLGS population and evaluated for nutritional status. Trained personnel through the 2-day dietray recall performed dietary assessment. Household values were converted to gram values, which were eventually converted to serving. Statistical analyses were done using the SPSS. Student t-test was used to test differences in means between sex groups and Chi-square test was used to determine the association of meeting the food guide pyramid recommendations with sex. Daily mean intakes of pyramid food groups were: bread and cereals 8.6±3.3 (the recommended number of servings 6-11) vegetables 3.7±2.0 (recommended number of servings 3-5) fruits 3.0±2.5 (recommended number of servings 2-4) dairy products 1.1±0.8 (recommended number of servings 2-3) meat and its alternatives 1.3±0.7 (recommended number of servings 2-3) and fats and sweets 7.1±2.7 (no recommendation). There were significant statistical differences between men and women for intakes of the following groups: grains (P<0.001), dairy products (P<0.01), meats and substitutes (P<0.001) and fats and sweets (P<0.001). In all of the above-mentioned, the mean intakes of the pyramid food groups in men were higher than in women. In about 80% of the population studied, the daily intakes of meat and dairy products were less than those recommended by the food guide pyramid. This study revealed that, as compared to recommendations of the food guide pyramid, daily mean intakes of various food groups were as follows: Bread and cereal servings were close to recommended dietary values, for vegetables the values slightly exceeded minimum recommendations, for fruits these values were the same as those recommended, but the closer we got to the pyramid peak the similarity in servings decreased such that for meat and its alternatives, and dairy groups they were lower than those recommended. For fats and sweets the daily mean intakes were very high. Taking the above results into consideration, the importance of public education aiming at modification of current nutritional habits to fit in with a standard food guide pyramid is strongly recommended. 1) Food Guide Pyramid 2) Serving 3) Food groups 4) Dietary Intake 2003 3 01 767 778 http://rjms.iums.ac.ir/article-1-1694-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 EVALUATION OF THE CORRELATION OF CENTRAL CORNEAL THICKNESS AND INTRAOCULAR PRESSURE MEASURED BY GOLDMAN TONOMETER M.M. Mirsamadi N. Sinehsepehr To determine the effect of central corneal thickness (CCT) on measured intraocular pressure (IOP) and evaluating the relationship between them in each of the groups of patients including: Normal subjects, ocular hypertension patients and patients with primary open angle glucoma (POAG). Correlation between intraocular pressure (Measured by Goldman applanation tonometer) and central corneal thickness (Measured by ultrasond pachymetry) were studied in 48 Normal subjects, 19 patients with ocular hypertension and 30 POAG patients. Correlation between CCT and IOP was evaluated in each group seperately and also Mean CCT of each group was compared between all three groups. Mean central corneal thickness in ocular hypertension (OHT) patients was 570±18.6μm and in POAG patients was 530±20.4μm and in normal subjects was 537±18μm. CCT in the ocular hypertension group was significantly(P=0.000) higher than Normal subjects or POAG patients. There was no significant difference in CCT between the latter 2 groups. Simple regression analysis showed statisticaly significant correlation between IOP and CCT in Normal subjects (P=0.002) and OHT patients (P=0.028) but not in POAG patients. Linear regression analysis showed an increase of 0.43mmHg in IOP with each 10 μm increase in CCT in Normal subjects group. The results of the present study are consistent with other studies and indicates that intraocular pressure measured with applanation tonometer is positively related to central corneal thickness, so that IOP is overestimated in patients with thick corneal. Therefore, CCT is an important variable for accurate assessment of IOP and it is desirable to check the CCT on patients suspected of having glucoma and/or ocular hypertension. 1) Central corneal thickness 2) Primary open angle glaucoma 3) Iop 4) Ocular hypertention 2003 3 01 779 786 http://rjms.iums.ac.ir/article-1-1695-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 FOOD CONSUMPTION PATTERN AND DIETARY HABITS IN HOUSEHOLD RESIDENT IN WEST AREA OF TEHRAN AND THE DIFFERENCES BETWEEN THEM SH. Najmabadi R. Jamshidi   In this descriptive cross sectional survey with main purpose to assess and compare food consumption pattern and food habits of household resident in different area in west of Tehran where the public health is supervised by Iran University of Medical Sciences and Health Services. 1149 house hold cases were selected by random stratified cluster sampling. Sammpling method was designed to compare the patern of food consumption and food habits in different area. Data collection was done by interview using the food frequency questionaire. The results show some of socioeconomic characters in the studied household had significantly difference. (Number of children, number of family in household, number of room in their house, expenditure of food in house-hold…) Food consumption and food habits in different area was significantly difference. The frequency of daily consumption of milk and dairy product in studied house holds is significantly difference(P.V<0.0001). For example area No 2 only 1.8% of house holds had no daily consumption of milk group and area No 18 so did in 14.3% of house holds. Also the frequency of daily consumption of vegetable and fruits group in studied households is significantly difference (P.V<0/0001). Also eating behavior from out-side the home in studied house holds in different area is significantly difference. Food habits in studied households in frequency of eating out-side meal is difference. 1) Food consumption pattern 2) Food groups 3) Dietary 4) Different eating behavior 5) side meal 2003 3 01 787 800 http://rjms.iums.ac.ir/article-1-1696-en.pdf
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Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2003 9 32 PURIFICATION AND EVALUATION OF MAJOR HYDATID CYST FLUID ANTIGENS IN IMMUNODIAGNOSIS OF HYDATIDOSIS A. Haniloo J. Masoud B. Farzami     Regarding remarkable prevalence of human hydatidosis and despite introduction of novel sensitive techniques such as ELISA for immunodiagnosis of disease in the word, there has not been much progress in that field in Iran. Preparation and purification of suitable antigens is the basic and first step in serodiagnosis of this disease. The present study, thus, is designed and carried out for preparation, purification and evaluation of major hydatid fluid antigens in immunodiagnosis of hydatidosis. Among the various methods for pirification of antigens, we used gel filtration chromatography, anion exchange chromatography and partial purification of antigen B procedure. Elution of crude hydatid fluid antigen (CHFAg) sample through gel filtration and anion exchange columns resulted in four separately peaks from each of columns. To evaluate the diagnostic value of CHFAg and purified antigens by ELISA, we tested 64 sera from patients who had hydatid cyst disease, 55 sera from patients with fascioliasis and toxocariasis, 50 sera from various malignancies and 73 sera from healthy controls. Despite low specificity of the CHFAg-ELISA(83%) owing to non specific reactions with some cases of non-hydatid sera, its sensitivity was relatively high (94%). Although, CHFAg-ELISA may be useful for primary screening in seroepidemiological studies, but we suggest ELISA using the first antigenic peak of gel filtration(PlG-ELISA), which exhibits nearly equal sensitivity wich CHFAg, and relatively high specificity of 87% Among the purified antigens, Antigen B of Oriol procedure and second antigenic peak of gel filtration (P2G) showed the highest specificity of 98% and 96% respectively. In conclusion, we suggest that the P1G-ELISA, which exhibits a relatively high sensitivity, be convenient for primary screening test and AgB-ELISA or P2G-ELISA can be considered as confirmatory tests for specific immunodiagnosis of hydatidosis. 1) Hydatidosis 2) ELISA 3) Antigen 4) Immunodiagnosis 2003 3 01 801 810 http://rjms.iums.ac.ir/article-1-1698-en.pdf