2024-03-29T10:57:39+04:30 http://rjms.iums.ac.ir/browse.php?mag_id=179&slc_lang=en&sid=1
179-5074 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2019 25 11 The effect of eight weeks of pilates training and consumption of β-glucan on plasma concentrations of obestatin and cholecystokinin in overweight women Raziyeh Auobi Asl r.auobi.62@gmail.com Farzaneh Taghian f.taghian@khuisf.ac.ir Background: The aim of this study was to compare the effect of eight weeks of pilates exercise and consumption of β-glucan on the plasma level of obestatin and cholecystokinin in overweight women. Methods: In this semi-experimental study, 32 women with a mean age of 39.70±6.63 years, height 157.85±6.30 cm, weight 69.38±6.25 kg, and body mass index 27.76±1.51 kg/m2 were randomly divided into four groups including: control, pilates training, barley bread and combination. Firstly, blood samples were collected from subjects for measuring obestatin and colostomyolone levels. Then, pilates and combined groups were exposed to pilates training (8 weeks, 3 sessions per week, each session for 1 hour). The combined group and barley group received one barley of 5 grams of beta-glucan for 8 weeks (once a day). The control group received no intervention. Abestatin and cholecystockinin levels were measured by ELISA method after 8 weeks of pilates training. For comparison, t-test for paired comparison and analysis of variance test (ANOVA) were used for comparison between groups (significant level p<0.05). Results: The results showed no significant changes after 8 weeks of pilates training and consumption of β-glucan barium in any of the study groups (p>0.05). But there was a significant increase in cholecystokinin in the combined group and barley group (p≤0.05). Conclusion: Based on this study eight weeks of training pilates and consumption of barley beta-glucan causes a significant increase in cholecystokinin plasma levels in overweight women.   Pilates β-glucan barley Obestatin Cholecystokinin 2019 2 01 1 12 http://rjms.iums.ac.ir/article-1-5074-en.pdf
179-5362 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2019 25 11 Association of supraspinatus tendon thickness with clinical examination and quality of shoulder function and MRI in patients with partial tear of supraspinatus tendon Haleh Dadgostar dadgostar.h@iums.ac.ir Farinaz Fahimi Pour FahimiPour.f@iums.ac.ir Alireza Pahlevan Sabagh pahlevansabagh.ariums.ac.ir Navid Moghadam navid.mgd@gmail.com Shafieh Movasseghi movaseghi@gmail.com Background: Partial tear of supraspinatus tendon is one of the most common causes of shoulder pain. Following history and clinical examination, MRI is the standard diagnostic method. The aim of this study was to evaluate the accuracy of the clinical tests and quality of function of shoulder and comparison of the thickness of the supraspinatus tendon measured on ultrasound with the results of MRI performed among patients with partial tear of supraspinatus tendon. Methods: 58 patients with rotator cuff tendinopathy criteria (from 2013 to 2016) entered the study. The clinical examination (Jobe, Hawkins, Neer, O'Brien، Lift Off, Belly Press), quality of function (by DASH and WORC questionnaire), ultrasound (to evaluate supraspinatus tendon thickness), and MRI were performed and data were analyzed with SPSS version 23 for association. Results: In our study, 58 patients were evaluated (81% female, 55.53 years mean age). The result of KS test was not significant (p=0.200). The clinical examination and quality of function and thickness of supraspinatus tendon were not related (p>0.05). Although higher average thickness of supraspinatus tendon in case of partial tear was observed on MRI, there was no significant difference (p>0.05). Conclusion: Considering the findings, in cases of partial tear of supraspinatus muscle tendon, in addition to clinical tests and functional quality evaluation, paraclinical tests such as MRI and ultrasound are necessary to confirm the diagnosis.     Partial tear Supraspinatus Magnetic Resonance imaging Ultrasound 2019 2 01 13 22 http://rjms.iums.ac.ir/article-1-5362-en.pdf
179-5337 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2019 25 11 Evaluation of determinants of mortality in patients undergoing coronary artery bypass graft surgery in Urmia Seyed-al-Shohada Heart Center Behnam Askari askaribehnam@ymail.com Hamid Mehdizadeh hamidmehdizadeh44@gmail.com safa koomasi safakoomasi1992@yahoo.com Background: Cardiovascular diseases are the leading cause of mortality in Iran and in the world. There is a controversy about risk factors and causes of mortality following Coronary Artery Bypass Graft (CABG) surgery and the purpose of this study is to determine these factors. Methods: In the retrospective case-control study, from March 2010 to July 2016 preoperative and intraoperative clinical data's of CABG patients were obtained and analyzed. Case group included 36 patients who died during the 30 days after operation and control group included 144 patients who had not died after surgery. Results: The mortality rate during this interval was 1.29% (36/2774). Old age, female sex, three vessel disease, chronic obstructive pulmonary disease, left main involvement, mitral valve regurgitation, emergency surgery, preoperative critical condition, low hemoglobin level, high white blood cell count, peripheral vascular disease, high aortic cross clamping time, pulmonary hypertension, high cardiopulmonary bypass time, intra-aortic balloon pump placement and use of inotrope and pacemaker had a significant relationship with mortality. Conclusion: Emergency surgery has a high mortality in the patients with preoperative critically ill conditions, especially in older women with multiple comorbidities. Preoperative precise assessment and correcting factors such as anemia, controlling inflammatory and pulmonary diseases, and reducing the duration of surgery is recommended to reduce mortality after surgery. Coronary artery disease Coronary artery bypass grafting Mortality 2019 2 01 23 33 http://rjms.iums.ac.ir/article-1-5337-en.pdf
179-4536 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2019 25 11 Knowledge, attitudes and practice of breast self-examination among over 20-year females in Tehran Hamidreza Paknejad paknejad.hamidreza@yahoo.com vahid saeedi vahidsaeedi1988@gmail.com Background: Breast cancer is the most common cancer in Iranian women. Early detection of breast cancer is effective in reducing its mortality rate. The easiest and cheapest way for early detection of this disease is Breast self-examination (BSE). Therefore this study, investigates the knowledge, attitudes and practice of BSE among over 20 years female. Methods: This descriptive cross sectional study was done among over 20 years female in Tehran, years 2015-16. The method of sampling was convenience sampling. With KAP questionnaire knowledge, attitude and practice of these participants was assessed. The collected data were analyzed using descriptive and inferential statistics methods. Results: The mean age of participants was 32.51 years. In part related to breast cancer knowledge 40.57% and in part related to BSE knowledge 23.03% of participants had good knowledge. 47.86% of participants had positive attitudes, but only 11.6% of them performed BSE regularly every month. Conclusion: finding of this study showed the participants have inappropriate knowledge, attitude and performance about BSE. So it seems necessary to devise and implement various educational and interventional programs in Health Centers to promote public awareness regarding preventive behaviors and particularly self examination.     Knowledge Attitude Practice Breast cancer BSE 2019 2 01 34 41 http://rjms.iums.ac.ir/article-1-4536-en.pdf
179-5046 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2019 25 11 Determination of benomyl and diazinon residues in strawberry and its related health implications Somayeh Abdi s.abdi@iauh.ac.ir Soheil Sobhan Ardakani soheil_sobhan@yahoo.com Background: Nowadays, since the pesticide residues in food products can cause adverse effect on the human health, this study was carried out to determine benomyl and diazinon residues in strawberry and also related health risk assessment. Methods: In this descriptive study, a total of thirty specimens of greenhouse strawberries were collected from market basket of city of Hamedan. After preparation and processing the samples in the laboratory, benomyl and diazinon residues were determined using spectrophotometer at wavelength 400 nm for benomyl and 245 nm for diazinon in three replications. Also, health risk assessment was computed according to health risk assessment model. Results: The results showed that among the analyzed strawberry samples benomyl was detected in amounts ranging from 0.013 mg/kg to 0.989 mg/kg, and diazinon ranged from 0.01 mg/kg to 1.416 mg/kg. Also, the mean levels of both pesticide residues in strawberry samples were higher than the Maximum Residue Levels (MRL) established by WHO, and also the EU. On the other hand, although the value of the MOET index with 180.51 indicates the cumulative risk of benomyl and diazinon pesticides in strawberries, based on the results of health index, there are no potential health concerns through consuming of strawberry from the study area. Conclusion: Although the results of this study showed that there are no potential health risks for consumers through consuming of strawberry, with increasing use of chemical pesticides for farm and garden products, to achieve food safety, regular monitoring of pesticide residues in foodstuffs is recommended. Benomyl Diazinon Food safety Health risk Strawberry 2019 2 01 42 51 http://rjms.iums.ac.ir/article-1-5046-en.pdf
179-5164 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2019 25 11 Expression of SO6-STxB gene cassette in Escherichia coli and investigation of antibody titer Masoud abdollahi ma.abdollahi102@yahoo.com Hossien Honari honari.hosein@gmail.com Seyed masih e'temad aubi masih.etemadi@gmail.com Background: One of the ways to strengthen the effect of vaccines is the use of adjuvant. STxB has a carrier role and can act as an adjuvant; thus it can be fused with vaccine candidate antigens in order to produce efficient vaccines. Saponaria officinalis is a plant that has shown N-glycosidase activity. SO6 isoform of this plant, depurinates the adenine 4324 in the conserved sequence GAGA in 28SrRNA and disrupts protein synthesis. The aim of this study was expression of SO6-STxB gene in Escherichia coli (E. coli) and investigation of antibody titer in mice. Methods: In this study SO6 gene with BamHI and SalI restriction enzyme sites were isolated from pUC57 plasmid and subcloned into pET28a (+) -STxB expression vector and transferred to E. coli BL21 (DE3). Expression of SO6-STxB gene cassette was induced by IPTG and purified by nickel affinity chromatography. The recombinant protein was confirmed by western blotting. Mice were immunized intraperitoneally with purified protein and serum IgG titers were measured by ELISA. Results: Subcloning of SO6–STxB gene in pET28a (+) expression vector was confirmed by PCR and enzyme digestion reaction. A 37/5 kDa recombinant protein was confirmed by SDS-PAGE and western blotting. The antibody generated from mouse serum was isolated and confirmed by ELISA. Conclusion: Purified recombinant antigen STxB-SO6 can be used for research and be a suitable anti-cancer vaccine candidates.   STxB Sigella Saponaria Officinalis N-glycosidase activity SO6 2019 2 01 52 60 http://rjms.iums.ac.ir/article-1-5164-en.pdf
179-5184 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2019 25 11 Family-based tele-intervention of SPARK program on motor proficiency and severity of autism symptoms in children with high functioning autism spectrum disorder: A pilot study Louisa Aqdassi louisa@gmai.com Hamid Reza Pouretemad h-pouretemad@sbu.ac.ir Jalil Fathabadi fathabadi@gmail.com Saeid Sadeghi saeidsadeghi.psychologist@gmail.com Background: The aim of the present study was to evaluate any possible effects of family-based tele-intervention of the SPARK program for improving the motor proficiency and reducing the severity of autism symptoms in children with high-functioning ASD. Methods: This research was a quasi-experimental study with pretest-post test design without a control group. Nine families of children with high-functioning ASD were recruited from rehabilitation centers for children with ASD in Tehran, Isfahan, Ghods and Kermanshah cities. The tele-rehabilitation procedure was administered by the parent to their children during 24 sessions each 45 minutes for 8 weeks. The Gilliam Autism Rating Scale (GARS) (Gilliam, 1995) and short form of Bruininks-Oseretsky Test of Motor Proficiency (BOTMP) (Bruininks, 1978) were used for data collection. Data were analyzed using pair t test. Results: The results demonstrated that (p< 0.5) family-based tele-intervention of SPARK program has significant effect in motor proficiency, but this effect was not significant in reducing the severity of autism symptoms in children with high-functioning. Conclusion: The results of this study showed that family-based tele-rehabilitation has appeared to be an effective intervention to reduce motor problems in children with autism spectrum disorders.   Tele-intervention Family-based SPARK Motor proficiency Autism symptoms 2019 2 01 61 71 http://rjms.iums.ac.ir/article-1-5184-en.pdf
179-5193 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2019 25 11 The effect of eight weeks interval aerobic exercise and consumption of green tea supplementation on oxidative stress indices of inactive young girls Fereshte Shahidi com.yahoo@ Angleshahidi Chonur Shakeri shakeri.chonur65@gmail.com Zohreh Delfani z.delfani@sru.ac.ir Background: Not having physical activity with a physiological function disorder and reducing the body's resistance to oxidative stress. The green tea supplement increases plasma antioxidant defense system during rest and during exercise. The purpose of this study was to determine the effect of eight weeks of periodic aerobic exercise and green tea supplementation on oxidative stress indices in young girls inactive. Methods: The present semi-experimental study was carried out in the form of a pre and post design test. The statistical population consisted of all inactive young girls in Sanandaj city. 30 volunteers were randomly selected and divided into three groups of 10, including Practice-supplements, Practice-placebo and supplement alone. The periodic aerobic exercise program increased over the course of eight weeks, triple periods/week. Primary blood samples were taken at baseline before the start of supplementation, and the second blood samples were taken 48 hrs following the end of the 8-week activity. The Total Antioxidant Capacity (TAC) and Malondialdehyde (MDA) were measured using ELISA kit. One-way analysis of variance (ANOVA) with Tukey's post hoc test and t-test with significant level of p≤0.05 were used. Results: There was a significant difference in MDA between the three groups. With MDA, the practice-placebo group showed a significant difference with the supplement group. However, in the TAC index, no significant difference was observed between the three groups in the post-test phase. Based on the results of t-test, the MDA index decreased significantly in all three groups, but the TAC index decreased significantly in the supplementation group. Conclusion: Regular physical activity seems to work like a supplemental anti-oxidant supplement which in stressful conditions maintains and improves the health of the person and addition of green tea supplement doubles the effect.     interval aerobic exercise supplements of green tea Oxidative stress indices girls inactive. 2019 2 01 72 84 http://rjms.iums.ac.ir/article-1-5193-en.pdf
179-5276 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2019 25 11 Comparison of the physical and biological dose of oxygen ions and proton in hadron therapy Ladan Rezaee rezaie_l@iaushiraz.ac.ir Background: In radiation therapy, oxygen ions have more biological benefits than lighter ions such as proton. Oxygen has a higher Linear Energy Transfer (LET) and a larger Relative Biological Effectiveness (RBE). To design the Spread-Out Bragg Peak (SOBP) of biological doses, we have developed a functional approach with Monte Carlo calculations and matrix computations. We have used this method for both oxygen and proton beams. Methods: After obtaining the profiles of the Bragg Peak by Geant4 code, intensity weighing factors for each beam was calculated to create a uniform SOBP. Also, the RBE value was calculated according to the Linear-uQadratic model (LQ). Biological dose, physical dose, and cell survival levels were also obtained in the radiation of both ions. Results: The designed biological SOBP has a good uniformity. Physical dose derived from proton and oxygen beams do not differ significantly, but for biological dose, there is a sharp difference between them. Even with the modulation of the intensity of the beams to produce the same biological dosage, the cell survival levels chart will vary greatly.  Conclusion: The biological properties and effects of oxygen in respect to the proton can be a good choice to optimize the system to maximize damage to the tumor tissue and minimize damage to surrounding healthy tissues. The existence of richer tables of experimental values for the effective parameters on the amount of relative biological effectiveness greatly increases the accuracy of this optimization.     Hadron therapy Geant4 Code Physical dose Biological dose Relative biological effectiveness 2019 2 01 85 97 http://rjms.iums.ac.ir/article-1-5276-en.pdf
179-5290 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2019 25 11 Comparison of ultrasound and MRI of the shoulder in determining the location and severity of rupture of the main tendon of the rotator cuff Seyed Reza Saadat Mostafavi rezasaadat6697@gmail.com Mohammadreza Hosseini amin.mr.hoseini@gmail.com Background: The study of shoulder pathologies as one of the most common orthopedic injuries due to the lack of sensitivity of clinical findings is one of the topics discussed in radiology papers. Traditionally, MRI is a selective diagnostic modality of choice. However, due to its limitations, such as high cost and unavailability, simple and cheaper methods seems to be valuable. Sonography can be a good alternative in this field that examines soft tissue pathologies. This study evaluated the magnitude of ultrasound and MRI matching in cases of partial and complete tear of cuff muscles and accompanying findings such as subacromial bursal effusion and degenerative changes of shoulder joint. Methods: In this study 85 patients who referred to the radiology department of Hazrat-e-Rasool Akram Hospital were asked for simultaneous sonographic examination of the shoulder. The degree of ultrasound and MRI correlation in localizing the tear as well as the severity of tear based on complete or partial was evaluated for each rotator cuff muscle individually. Also the degree of subacromial bursa effusion and acromioclavicular join hypertrophy were also compared. Results: A total of 85 patients (30 males and 55 females) with different injuries in supraspinatus, infraspinatus, subscapularis and long head of biceps tendon, sonography was in acceptable agreement with the findings of MRI in the diagnosis of complete and partial tear and in determining their location. However, the tendency of tendon retraction is less than predicted by MRI. Conclusion: Shoulder ultrasound can be used as an alternative modality to MRI, especially in cases where it is not available, to examine the rupture of cuff tendons, as well as the extent and severity of subacromial bursa effusion and acromioclavicular joint hypertrophy.   Clinical evaluation Nursing Direct observation of clinical skills (DOPS) Clinical skills 2019 2 01 98 107 http://rjms.iums.ac.ir/article-1-5290-en.pdf
179-5387 2024-03-29 10.1002
Razi Journal of Medical Sciences RJMS 2228-7043 2228-7051 2019 25 11 Investigating clinical and laboratory findings in patients with drug-resistant and drug-sensitive tuberculosis in Masih Daneshvari Hospital Atefeh Sadeghi Shermeh Atefeh.sadeghi.sh@gmail.com Ali Akbar Delbandi delbandi@yahoo.com Payam Tabarsi p.tabarsi@sbmu.ac.ir Esmaeil Mortaz emortaz@gmail.com Majid Khoshmirsafa Khoshmirsafa.m@tak.iums.ac.ir Mohammad Reza Bolouri Bolouri.mr@gmail.com Elham Alipour fayez Elhaam.alipour@gmail.com Mehdi shekaarabi M_shekarabi@yahoo.com Background: Although tuberculosis (TB) is often curable, it remains one of the top 10 major causes of death worldwide. Unfortunately, in recent decades, the emergence of Mycobacterium tuberculosis (Mtb) strains resistant to anti-TB drugs (DR-TB) is one of the most critical factors in the treatment of tuberculosis. Therefore, the present study addresses the epidemiologic factors, laboratory and clinical findings affecting the development of tuberculosis and, in particular, resistant forms of it. Methods: In this study, laboratory and clinical data were collected from 67 patients with drug-susceptible TB (DS-TB), 20 patients with DR-TB admitted to the Masih Daneshvari hospital and 30 healthy controls during one year (2015-16). The disease was confirmed by an infectious specialist according to clinical history, physical examination, radiological and laboratory findings. TB patients were divided into two groups: DS-TB and DR-TB, based on how they responded to treatment. Statistical analysis was performed using SPSS software. Results: The incidence of DR-TB is associated with several factors, including history of previous treatment and contact with the TB patient. There were also significant differences between the three groups regarding the rate of erythrocyte sedimentation (ESR), C-reactive protein (CRP) and adenosine deaminase (ADA). Conclusion: According to the results, it is recommended that in high risk patients (with a history of previous treatment and contact with the TB patient, etc.), treatment should be done with greater accuracy and sensitivity. Also, attention to the differences in the clinical and laboratory findings of two DS and DR-TB groups may help in diagnosis and better treatment of the disease.   Drug-resistant tuberculosis Drug-susceptible tuberculosis Laboratory findings Clinical findings 2019 2 01 108 117 http://rjms.iums.ac.ir/article-1-5387-en.pdf