fa بررسی ارتباط سطح پروتئین c واکنش فاز حاد و مرگ و میر در بخش مراقبت‌های ویژه بیماریهای داخلی Internal Medicine پژوهشي Research <font face="Times New Roman" size="3">&nbsp;</font> <p class="MsoNormal" dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify line-height: normal unicode-bidi: embed direction: rtl text-justify: kashida text-kashida: 0%"><b><span 10pt="" 9.0pt="" b="" font-size:="" lang="AR-SA" mso-ansi-font-size:="" mso-ascii-font-family:="" mso-hansi-font-family:="" new="" span="" style="font-family: " times="">:<b>&nbsp;</b></span><span 10.0pt="" 10pt="" 9.0pt="" 9pt="" b="" dir="ltr" fa="" font-size:="" lang="FA" mso-ansi-font-size:="" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-bidi-font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-hansi-font-family:="" new="" span="" style="font-family: " times=""><span dir="rtl"></span><span dir="rtl"></span> و مرگ و میر در بخش مراقبت های ویژه می باشد.<!--stripped--><!--stripped--></span></b></p> <b><font face="Times New Roman" size="3">&nbsp;</font></b> <p class="MsoNormal" dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify line-height: normal unicode-bidi: embed direction: rtl text-justify: kashida text-kashida: 0%"><b><b><span 10pt="" 9.0pt="" b="" fa="" font-size:="" lang="FA" mso-ansi-font-size:="" mso-ascii-font-family:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-hansi-font-family:="" new="" span="" style="font-family: " times="">: این مطالعه، یک مطالعه گذشته نگر می باشد که بر روی پرونده 150 بیمار بستری در بخش مراقبت های ویژه انجام شده است. در این مطالعه سن، جنس، بیماری زمینه ای،ارگان دچار اختلال و سطح </span><span 10.0pt="" 9pt="" b="" dir="ltr" fa="" font-size:="" mso-bidi-font-family:="" mso-bidi-font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="font-family: " times="">CRP</span><span dir="rtl"></span><span dir="rtl"></span><span .="" 10.0pt="" 10pt="" 9.0pt="" 9pt="" b="" dir="ltr" fa="" font-size:="" lang="FA" mso-ansi-font-size:="" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-bidi-font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-hansi-font-family:="" new="" span="" spss="" style="font-family: " times=""><span dir="rtl"></span><span dir="rtl"></span> و تست فیشر جهت تعیین ارتباط متغیرها صورت گرفت. و 0.05></span><span 10.0pt="" 9pt="" b="" dir="ltr" fa="" font-size:="" mso-bidi-font-family:="" mso-bidi-font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="font-family: " times="">p</span><span dir="rtl"></span><span dir="rtl"></span><span 10pt="" 9.0pt="" b="" class="MsoNormal" dir="rtl" fa="" face="Times New Roman" font="" font-size:="" lang="FA" mso-ansi-font-size:="" mso-ascii-font-family:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-hansi-font-family:="" new="" p="" size="3" span="" style="font-family: " times="">یافته</span></b><b><span 10.0pt="" 9pt="" b="" dir="ltr" fa="" font-size:="" mso-bidi-font-family:="" mso-bidi-font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="font-family: " times="">‌</span></b><b><span 10pt="" 9.0pt="" b="" fa="" font-size:="" lang="FA" mso-ansi-font-size:="" mso-ascii-font-family:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-hansi-font-family:="" new="" span="" style="font-family: " times="">: میانگین سنی بیماران، 4/15</span><span 10pt="" 9.0pt="" fa="" font-size:="" lang="FA" mso-ansi-font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="font-family: " times="">&plusmn;</span><span .="" 10.0pt="" 10pt="" 36="" 71="" 79="" 9.0pt="" 97="" 9pt="" b="" dir="ltr" fa="" face="B Mitra" font="" font-size:="" lang="FA" mso-ansi-font-size:="" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-bidi-font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-hansi-font-family:="" new="" size="2" span="" style="font-family: " times=""><span dir="rtl"></span><span dir="rtl"></span> با میزان مورتالیتی بیماران ارتباط معنی داری دارد</span><span dir="ltr"></span><span dir="ltr"></span><span 10.0pt="" 9pt="" b="" dir="ltr" fa="" font-size:="" lang="FA" mso-bidi-font-family:="" mso-bidi-font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="font-family: " times=""><span dir="ltr"></span><span dir="ltr"></span> </span><span dir="rtl"></span><span dir="rtl"></span><span 10.0pt="" 10pt="" 9.0pt="" 9pt="" b="" dir="ltr" fa="" font-size:="" lang="FA" mso-ansi-font-size:="" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-bidi-font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-hansi-font-family:="" new="" span="" style="font-family: " times=""><span dir="rtl"></span><span dir="rtl"></span>></span><span 10.0pt="" 9pt="" b="" dir="ltr" fa="" font-size:="" mso-bidi-font-family:="" mso-bidi-font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" new="" style="font-family: " times="">p</span><span dir="rtl"></span><span dir="rtl"></span><span 10pt="" 9.0pt="" b="" class="MsoNormal" dir="rtl" fa="" face="Times New Roman" font="" font-size:="" lang="FA" mso-ansi-font-size:="" mso-ascii-font-family:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-hansi-font-family:="" new="" p="" size="3" span="" style="font-family: " times="">نتیجه گیری</span></b><span 10.0pt="" 10pt="" 9.0pt="" 9pt="" b="" dir="ltr" fa="" font-size:="" lang="FA" mso-ansi-font-size:="" mso-ascii-font-family:="" mso-bidi-font-family:="" mso-bidi-font-size:="" mso-bidi-language:="" mso-fareast-font-family:="" mso-hansi-font-family:="" new="" span="" style="font-family: " times=""><span dir="rtl"></span><span dir="rtl"></span> با میزان مورتالیتی ارتباط مستقیم و مستقل دارد. لذا سنجش سطح سرمی آن در بیماران بستری در بخش مراقبت های ویژه در تعیین پیش آگهی آنها کمک کننده است ،هرچند برای تأیید مطلب فوق نیاز به مطالعات گسترده تری در این زمینه است.<!--stripped--><!--stripped--></span></b></p> <b><font face="Times New Roman" size="3">&nbsp;</font></b> <p class="MsoNormal" dir="rtl" style="margin: 0cm 0cm 0pt text-align: justify line-height: normal unicode-bidi: embed direction: rtl text-justify: kashida text-kashida: 0%"><b><span lang=&quot;FA&quot; style=&quot;font-family: &quot; b=&quot;&quot; mitra&quot;=&quot;&quot; font-size:=&quot;&quot; 10pt=&quot;&quot; mso-ansi-font-size:=&quot;&quot; 9.0pt=&quot;&quot; mso-ascii-font-family:=&quot;&quot; &quot;times=&quot;&quot; new=&quot;&quot; roman&quot;=&quot;&quot; mso-hansi-font-family:=&quot;&quot; mso-bidi-language:=&quot;&quot; fa=&quot;&quot; mso-fareast-font-family:=&quot;&quot; roman&quot;&quot;=&quot;&quot;><font size="2">&nbsp;</font></b></p> <b><font face="Times New Roman" size="3">&nbsp;</font></b> <font face="Times New Roman" size="3">&nbsp;</font> <p class="MsoNormal" style="margin: 0cm 0cm 0pt text-align: justify line-height: normal text-justify: kashida text-kashida: 0%"><b><span 12pt="" font-size:="" mso-bidi-language:="" new="" style="font-family: " times="">Background</span></b><span 12pt="" font-size:="" mso-bidi-language:="" new="" style="font-family: " times="">: The aim of this study was to investigation the relationship between CRP level and mortality in ICU patients.<!--stripped--><!--stripped--></span></p> <font face="Times New Roman" size="3">&nbsp;</font> <p class="MsoNormal" style="margin: 0cm 0cm 0pt text-align: justify line-height: normal text-justify: kashida text-kashida: 0%"><b><span 12pt="" font-size:="" mso-bidi-language:="" new="" style="font-family: " times="">Methods</span></b><span 12pt="" font-size:="" mso-bidi-language:="" new="" style="font-family: " times="">: In this retrospective cross-sectional study 150 critically patients in a university hospital was evaluated. Age, gender, organ failure and CRP level was evaluated. Then correlation between mortality and CRP level was measured.<!--stripped--><!--stripped--></span></p> <font face="Times New Roman" size="3">&nbsp;</font> <p class="MsoNormal" style="margin: 0cm 0cm 0pt text-align: justify line-height: normal text-justify: kashida text-kashida: 0%"><b><span 12pt="" font-size:="" mso-bidi-language:="" new="" style="font-family: " times="">Results</span></b><span 12pt="" font-size:="" mso-bidi-language:="" new="" style="font-family: " times="">: The mean age of patients was years. %47.3 of patients were men and %52.7 of patients were women. Prevalence of mortality in this study was %64.7.<!--stripped--><!--stripped--></span></p> <font face="Times New Roman" size="3">&nbsp;</font> <p class="MsoNormal" style="margin: 0cm 0cm 0pt text-align: justify line-height: normal text-justify: kashida text-kashida: 0%"><span 12pt="" font-size:="" mso-bidi-language:="" new="" style="font-family: " times="">In this study was demonstrated<font size="3"><font face="Times New Roman"><span style="mso-spacerun: yes">&nbsp;</span>that CRP concentration correlate with mortality (p<0.001).<!--stripped--><!--stripped--></font></font></span></p> <font face="Times New Roman" size="3">&nbsp;</font> <p class="MsoNormal" style="margin: 0cm 0cm 0pt text-align: justify line-height: normal text-justify: kashida text-kashida: 0%"><b><span 12pt="" font-size:="" mso-bidi-language:="" new="" style="font-family: " times="">Conclusion</span></b><span 12pt="" font-size:="" mso-bidi-language:="" new="" style="font-family: " times="">: In this study was revealed that CRP level was prognostic factor for mortality in critically ill patients.<!--stripped--><!--stripped--></span></p> <font face="Times New Roman" size="3">&nbsp;</font> پروتئین C, مورتالیتی C Protein, Mortality 47 52 http://rjms.iums.ac.ir/browse.php?a_code=A-10-1-1660&slc_lang=fa&sid=1 Samaneh Hatami سمانه حاتمی 3900319475328460043602 3900319475328460043602 No دانشگاه علوم پزشکی ایران، تهران، ایران Seyed Ali Javad Mousavi سیدعلی جوادموسوی javadmousavi.s@iums.ac.ir 3900319475328460043603 3900319475328460043603 No Iran University of Medical Sciences, Tehran, Iran دانشگاه علوم پزشکی ایران، تهران، ایران