fa گلومرولونفریت مزمن ایدیوپاتیک و حاملگی کلیه Nephrology پژوهشي Research <p>  در 98 بیمار مبتلا به گلومرولونفریت اولیه تاثیر بیماری کلیوی در نتیجه حاملگی و اثر حاملگی در سیر </p><p> <strong><i> Risk Factor </i></strong>نفروپاتی مادر مورد مطالعه قرار گرفت. بیماران از نظر داشتن، و یا همراه بودن سه<strong><i> </i></strong></p><p>  مهم فشار خون، نارسایی کلیوی و سندرم نفروتیک به 8 گروه تقسیم شدند. تاثیر گلومرولونفریت مزمن و </p><p> <strong><i> </i></strong>در نتیجه حاملگی بر مبنای افزایش مرگ و میر جنین، زایمان زودرس و توکسمی <strong><i>Risk Factor </i></strong>هر سه<strong><i> </i></strong></p><p>  حاملگی بررسی گردید و اثر حاملگی در تشدید نفروپاتی مادر بر مبنای افزایش غیر قابل انتظار سرم </p><p>  کراتی نین در دوران حاملگی و یا شش ماه بعد از ختم حاملگی ارزیابی شد. در این مطالعه مرگ و میر جنین </p><p>  در 36%، زایمان زودرس در 30%، مسمومست حاملگی در 21% و تشدید نفروپاتی مادر در 28% </p><p> <strong><i> </i></strong>و زایمان زودرس <strong><i>(P < 0.001) </i></strong>بیماران مشاهده گردید. مسمومست حاملگی در بیماران با فشار خون بالا <strong><i /></strong></p><p> <strong><i> </i></strong>ارتباط داشت ولی رابطه ای با سندرم <strong><i>(P<0.05) </i></strong><strong><i /></strong>و مسمومیت حاملگی <strong><i>(P<0.025) </i></strong>فشار خون بالا<strong><i> </i></strong></p><p>  نفروتیک بیمار و مرگ و میر جنین نشان نداد. </p> <div style="DIRECTION: ltr mso-element: frame mso-element-frame-width: 326.6pt mso-element-frame-height: 223.9pt mso-element-wrap: auto mso-element-anchor-horizontal: margin mso-element-left: 24.55pt mso-element-top: 146.95pt" align="left"><tbody><tr><td style="BORDER-BOTTOM: #f0f0f0 BORDER-LEFT: #f0f0f0 PADDING-BOTTOM: 0in BACKGROUND-COLOR: transparent PADDING-LEFT: 0in PADDING-RIGHT: 0in BORDER-TOP: #f0f0f0 BORDER-RIGHT: #f0f0f0 PADDING-TOP: 0in" height="299" valign="top" align="left"><p style="TEXT-JUSTIFY: inter-ideograph TEXT-ALIGN: justify LINE-HEIGHT: 16.05pt TEXT-INDENT: 14.85pt MARGIN: 0in 0in 0pt 0.2pt mso-element: frame mso-element-frame-width: 326.6pt mso-element-frame-height: 223.9pt mso-element-wrap: auto mso-element-anchor-horizontal: margin mso-element-left: 24.55pt mso-element-top: 146.95pt mso-line-height-rule: exactly" class="Style"><i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">The effect and outcome </span></i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">of <i>pregnancy in patients with chronic idiopathic glomerulonephritis was studied. The study population consisted </i>of </span><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 8.5pt mso-font-width: 114%">98 </span><i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">patients. All patients were divided into </span></i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 8.5pt mso-font-width: 132%">8 </span><i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">groups according </span></i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">to <i>presence, absence or coexistence </i>of </span><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 8.5pt mso-font-width: 132%">3 </span><i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">general risk </span></i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">factors <i>such as hypertension, renal failure and nephrotic syndrome. <p></p></i></span></p><p style="TEXT-JUSTIFY: inter-ideograph TEXT-ALIGN: justify LINE-HEIGHT: 16.05pt TEXT-INDENT: 14.85pt MARGIN: 0in 0in 0pt 0.2pt mso-element: frame mso-element-frame-width: 326.6pt mso-element-frame-height: 223.9pt mso-element-wrap: auto mso-element-anchor-horizontal: margin mso-element-left: 24.55pt mso-element-top: 146.95pt mso-line-height-rule: exactly" class="Style"><i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">The adverse effect </span></i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">of <i>renal disease and risk </i>factors <i>on the outcome </i>of <i>pregnancy was evaluated by increased incidence offetal death, toxemia and premature delivery. The influence </i>of <i>pregnancy on maternal nephropathy was evaluated by unexpected rise </i>of <i>serum creatinine from onset </i></span><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 8.5pt">of </span><i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">pregnancy upto six months post delivery. <p></p></span></i></p><p style="TEXT-JUSTIFY: inter-ideograph TEXT-ALIGN: justify LINE-HEIGHT: 16.05pt TEXT-INDENT: 14.85pt MARGIN: 0in 0in 0pt 0.2pt mso-element: frame mso-element-frame-width: 326.6pt mso-element-frame-height: 223.9pt mso-element-wrap: auto mso-element-anchor-horizontal: margin mso-element-left: 24.55pt mso-element-top: 146.95pt mso-line-height-rule: exactly" class="Style"><i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">There was high incidence </span></i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">of <i>fetal death </i></span><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 8pt">(36%), </span><i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">toxemia </span></i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 8pt">(27%), </span><i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">premature delivery (30%) and worsening </span></i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">of <i>maternal nephropathy </i></span><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 8.5pt">(28%). </span><i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">Toxemia was more common in hypertensives (P< 0.007) and premature delivery in patients with nephrolic syndrome (P<0.007). Worsening </span></i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">of <i>maternal nephropathy was correlated with renal failure (P<O.OS), hypertension (P<0.02S) and toxemia (P<0.007) but not with nephrotic syndrome </i></span><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9.5pt">or </span><i><span style="FONT-FAMILY: "Times New Roman","serif" FONT-SIZE: 9pt">with fetal death rate. <p></p></span></i></p></td></tr></tbody></table></div> 30 36 http://rjms.iums.ac.ir/browse.php?a_code=A-10-1-1257&slc_lang=fa&sid=1 Ahad Ghods احد قدس 3900319475328460020837 3900319475328460020837 Yes