fa اندازه‌گیری دوز جذبی کلیه‌ها، کبد، مثانه و تخمدان در آزمایش سنتی گرافی کلیه با رادیو داروهای 99mTc-EC و 99mTc-DTPA با استفاده از فنتوم به روش دوزیمتری ترمولومینسانس فیزیک‌پزشکی Biophysics پژوهشي Research <b style="mso-ansi-font-weight: normal"><span lang="FA"><p></p></span></b><p></p><h4 style="MARGIN: 0cm 0cm 0pt" dir="rtl"><span>    زمینه وهدف: هدف از این مطالعه اندازه‌گیری دوز رسیده به کلیه‌ها، مثانه، کبد و تخمدان در سنتی گرافی کلیه با رادیو داروی(</span><font face="Times New Roman"><span dir="ltr">Ethylene dicysteine</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="AR-SA"><span dir="rtl"></span>-</span><span dir="ltr"></span><span dir="ltr"><span dir="ltr"></span><font face="Times New Roman">99mTc </font></span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">(^99mTc-EC</span><span dir="rtl"></span></font><span style="FONT-FAMILY: "><span dir="rtl"></span> <span lang="FA"><font face="B Yagut">و مقایسه آن با دوز رسیده از رادیو داروی<br>(</font></span></span><span dir="ltr"></span><span dir="ltr"><span dir="ltr"></span><font face="Times New Roman">99mTc -Dietheylne Triamine Penta-Acid</font></span><span dir="rtl"></span><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span>)</span><span dir="ltr"></span>^{<span style="mso-bidi-language: FA" dir="ltr"><span dir="ltr"></span><font face="Times New Roman">99m</font></span>}<font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">Tc-DTPA </span><span dir="rtl"></span></font><span style="FONT-FAMILY: "><span dir="rtl"></span><font face="B Yagut"><span style="mso-spacerun: yes"> </span><span lang="FA">می‌باشد، که به طور متداول در سنتی گرافی کلیه از آن استفاده می‌شود.<p></p></span></font></span></h4><h4 style="MARGIN: 0cm 0cm 0pt" dir="rtl"><span>روش کار:</span><span style="FONT-FAMILY: " lang="FA"> این مطالعه از نوع کاربردی می‌باشد. در این پژوهش ابتدا از یک فنتوم آب با ابعاد هندسی مشابه بدن، متشکل از قسمت‌های تنه و شکم استفاده شد. در داخل قسمت‌های شکم و تنه، فنتوم‌های کلیه، کبد، مثانه و تخمدان از جنس </span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">Perspex</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> با ابعاد استاندارد مطابق با دستورالعمل 23 </span><span style="mso-bidi-language: FA" dir="ltr"><font face="Times New Roman">ICRP </font></span><span style="FONT-FAMILY: " lang="FA">ساخته و در داخل فنتوم شکم و تنه قرار گرفت. برای دوزیمتری از 30 تراشه مکعبی شکل لیتیم فلوراید دوزیمتر ترمولومینسانس (100</span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">TLD-</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span>) استفاده گردید. دوز رسیده به کلیه‌ها، کبد، مثانه و تخمدان‌ها با توزیع مقادیر متفاوت از رادیو داروهای </span><span dir="ltr"></span>^{<span style="mso-bidi-language: FA" dir="ltr"><span dir="ltr"></span><font face="Times New Roman">99m</font></span>}<font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">Tc-EC</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> و </span><span dir="ltr"></span>^{<span style="mso-bidi-language: FA" dir="ltr"><span dir="ltr"></span><font face="Times New Roman">99m</font></span>}<font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">Tc-DTPA</span><span dir="rtl"></span></font><span style="FONT-FAMILY: "><span dir="rtl"></span> <span lang="FA"><font face="B Yagut">که در کلینیک از آن‌ها استفاده<span style="mso-spacerun: yes">  </span>می‌شود، در قسمت‌های مختلف فنتوم قرار داده شده و دوز جذبی اندام و نیز دوز سطحی در ناحیه هر اندام اندازه‌گیری شد. سپس با اندازه‌گیری دوز جذبی پوست در نواحی کلیه‌ها، کبد، مثانه و تخمدان‌ها در 20 بیمار زن (10 بیمار برای هر رادیو دارو) تحت اسکن کلیه، دوز جذبی اندام‌های مذکور با استفاده از نتایج به دست آمده از فنتوم محاسبه گردید. در این طرح، نتایج با استفاده از نرم‌افزار آماری </font></span></span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">SPSS V.16</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> مورد تجزیه و تحلیل قرار گرفت؛ به طوری که ابتدا با استفاده از آزمون <span style="mso-spacerun: yes"><font face="B Yagut"> </font></span></span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">One-sample Kolmogorov-Smirnov</span><span dir="rtl"></span></font>^{<span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span><span style="mso-spacerun: yes"><font face="B Yagut">  </font></span></span>}<span style="FONT-FAMILY: " lang="AR-SA">نرمال بودن توزیع داده‌ها بررسی شد</span><span style="FONT-FAMILY: " lang="FA"> و سپس با استفاده از آزمون آماری </span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">t-test</span><span dir="rtl"></span></font><span style="FONT-FAMILY: "><span dir="rtl"></span> <span lang="FA"><font face="B Yagut">مقایسه‌ای بین مقادیر میانگین دوز جذبی بین دو گروه از بیماران تحت اسکن کلیه با دو رادیو دارو انجام گرفت.<p></p></font></span></span></h4><h4 style="MARGIN: 0cm 0cm 0pt" dir="rtl"><span>یافته‌ها: نتایج اندازه‌گیری دوز سطح پوست و دوز جذبی کلیه‌ها، کبد، مثانه و تخمدان هاارتباط خطی خوبی را با یکدیگر نشان می‌دادند. همچنین رابطه بین دوز جذبی و دوز سطح پوست اندام‌های مذکور با اکتیویته کل به کار رفته به صورت خطی تغییر می‌کرد. دوز جذبی محاسبه شده اندام‌های مورد نظر با رادیو داروهای </span><span dir="ltr"></span>^{<span dir="ltr"><span dir="ltr"></span><font face="Times New Roman">99m</font></span>}<font face="Times New Roman"><span dir="ltr">Tc-EC</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> و </span><span dir="ltr"></span>^{<span dir="ltr"><span dir="ltr"></span><font face="Times New Roman">99m</font></span>}<font face="Times New Roman"><span dir="ltr">Tc-DTPA</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> عبارتند از:<p></p></span></h4><h4 style="MARGIN: 0cm 0cm 0pt" dir="rtl"><span style="FONT-FAMILY: " lang="FA">الف: برای مثانه به ترتیب </span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">mrad/mCi</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> 74/0 </span><span style="mso-bidi-font-family: 'Times New Roman' mso-bidi-language: FA" lang="FA"><font face="Times New Roman">±</font></span><span style="FONT-FAMILY: " lang="FA">91/2 و </span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">mrad/mCi</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> 98/0</span><span style="mso-bidi-font-family: 'Times New Roman' mso-bidi-language: FA" lang="FA"><font face="Times New Roman">±</font></span><span style="FONT-FAMILY: " lang="FA">42/4 بود (٠٠١/٠</span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">p=</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span>).<p></p></span></h4><h4 style="MARGIN: 0cm 0cm 0pt" dir="rtl"><span style="FONT-FAMILY: " lang="FA">ب: برای کبد برای به ترتیب </span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">mrad/mCi</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span><font face="B Yagut"><span style="mso-spacerun: yes">  </span>019/0</font></span><span style="mso-bidi-font-family: 'Times New Roman' mso-bidi-language: FA" lang="FA"><font face="Times New Roman">±</font></span><span style="FONT-FAMILY: " lang="FA"> 58/1و </span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">mrad/mCi</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> 44/0</span><span style="mso-bidi-font-family: 'Times New Roman' mso-bidi-language: FA" lang="FA"><font face="Times New Roman">±</font></span><span style="FONT-FAMILY: " lang="FA"> 44/2 بود (٠٠٠/٠</span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">p=</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span>).<p></p></span></h4><h4 style="MARGIN: 0cm 0cm 0pt" dir="rtl"><span style="FONT-FAMILY: " lang="FA">ج: برای کلیه چپ در اسکن به ترتیب </span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">mrad/mCi</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> 14/0</span><span style="mso-bidi-font-family: 'Times New Roman' mso-bidi-language: FA" lang="FA"><font face="Times New Roman">±</font></span><span style="FONT-FAMILY: " lang="FA">60/2 و،</span><span dir="ltr"></span><span style="mso-bidi-language: FA" dir="ltr"><span dir="ltr"></span><font face="Times New Roman"> mrad/mCi</font></span><span dir="rtl"></span><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> 93/0</span><span style="mso-bidi-font-family: 'Times New Roman' mso-bidi-language: FA" lang="FA"><font face="Times New Roman">±</font></span><span style="FONT-FAMILY: " lang="FA"> 11/4 بود (٠٠٠/٠</span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">p=</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span>).<p></p></span></h4><h4 style="MARGIN: 0cm 0cm 0pt" dir="rtl"><span style="FONT-FAMILY: " lang="FA">د: برای کلیه راست در اسکن به ترتیب </span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">mrad/mCi</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> 036/0</span><span style="mso-bidi-font-family: 'Times New Roman' mso-bidi-language: FA" lang="FA"><font face="Times New Roman">±</font></span><span style="FONT-FAMILY: " lang="FA">67/2 و،</span><span dir="ltr"></span><span style="mso-bidi-language: FA" dir="ltr"><span dir="ltr"></span><font face="Times New Roman"> mrad/mCi</font></span><span dir="rtl"></span><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> 06/1</span><span style="mso-bidi-font-family: 'Times New Roman' mso-bidi-language: FA" lang="FA"><font face="Times New Roman">±</font></span><span style="FONT-FAMILY: " lang="FA"> 04/4 بود(٠٠٣/٠</span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">p=</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span>).<p></p></span></h4><h4 style="MARGIN: 0cm 0cm 0pt" dir="rtl"><span style="FONT-FAMILY: " lang="FA">ه: و برای تخمدان ها نیز به ترتیب </span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">mrad/mCi</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> 025/0</span><span style="mso-bidi-font-family: 'Times New Roman' mso-bidi-language: FA" lang="FA"><font face="Times New Roman">±</font></span><span style="FONT-FAMILY: " lang="FA">62/1 و ،</span><span dir="ltr"></span><span style="mso-bidi-language: FA" dir="ltr"><span dir="ltr"></span><font face="Times New Roman"> mrad/mCi</font></span><span dir="rtl"></span><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> 28/0</span><span style="mso-bidi-font-family: 'Times New Roman' mso-bidi-language: FA" lang="FA"><font face="Times New Roman">±</font></span><span style="FONT-FAMILY: " lang="FA"> 55/2 بود (٠٠٠/٠</span><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">p=</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span>).</span><span style="mso-bidi-language: FA" dir="ltr"><p></p></span></h4><h4 style="MARGIN: 0cm 0cm 0pt" dir="rtl"><span>نتیجه‌گیری:<font face="Times New Roman">�</font></span><span style="FONT-FAMILY: " lang="FA">به طورکلی نتایج حاصل از این تحقیق نشان می‌دهد که در بیماران تحت اسکن کلیه با رادیو داروی </span><span dir="ltr"></span>^{<span style="mso-bidi-language: FA" dir="ltr"><span dir="ltr"></span><font face="Times New Roman">99m</font></span>}<font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">Tc-EC</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> دوز جذبی کلیه‌ها، کبد، مثانه و تخمدان‌ها در مقایسه با دوز جذبی از رادیو داروی </span><span dir="ltr"></span>^{<span style="mso-bidi-language: FA" dir="ltr"><span dir="ltr"></span><font face="Times New Roman">99m</font></span>}<font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">Tc-DTPA</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> به طور قابل ملاحظه‌ای کمتر است. رادیو داروی </span><span dir="ltr"></span>^{<span style="mso-bidi-language: FA" dir="ltr"><span dir="ltr"></span><font face="Times New Roman">99m</font></span>}<font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">Tc-EC</span><span dir="rtl"></span><span style="FONT-FAMILY: IranNastaliq mso-bidi-language: FA mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman'" lang="FA"><span dir="rtl"></span><span style="mso-spacerun: yes">  </span></span></font><span style="FONT-FAMILY: " lang="FA">با توجه به مزایای دیگری مانند سهولت تهیه، کم هزینه بودن، برداشت کبدی ناچیز، دفع کلیوی سریع و تصاویر با کیفیت بالا که نسبت به رادیو داروی</span><span dir="ltr"></span>^{<span style="mso-bidi-language: FA" dir="ltr"><span dir="ltr"></span><font face="Times New Roman">99m</font></span>}<font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">Tc-DTPA</span><span dir="rtl"></span></font><span style="FONT-FAMILY: " lang="FA"><span dir="rtl"></span> دارد، می‌تواند به عنوان رادیو داروی مناسب در اسکن رادیوایزوتوپی کلیه در بخش‌های پزشکی هسته‌ای مورد استفاده قرار می‌گیرد.<p></p></span></h4> <p style="MARGIN: 0cm 0cm 0pt" class="MatnLatin"><font face="Verdana"><span><strong>    Background</strong>: In this survey the absorbed dose by kidneys, bladder, liver and ovaries with ^99mTc-EC (^99mTc</span><span dir="rtl"></span></font><span style="FONT-FAMILY: Arial mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="EN"><span dir="rtl"></span> </span><span lang="EN"><font face="Verdana">Ethylene dicysteine) renal scintigraphy was measured and compared with the absorbed dose from ^99mTc-DTPA (^99mTc - Dietheylne Triamine Penta-Acid), which often is used in renal scintigraphy.</font></span></p><p style="MARGIN: 0cm 0cm 0pt" class="MatnLatin"><font face="Verdana"><b><span lang="EN">Methods:</span></b><span lang="EN"> In this applicable study, we used a water phantom with geometrical sizes similar to that of human body and composed of thorax and hip. Then in accordance with </span><span style="mso-bidi-language: FA" lang="EN">International Committee on Radiation Protection</span><span lang="EN"> ICRP -23, we placed kidney, liver, bladder and ovary phantoms in to the thorax and hip parts. For dosimetry 30 cubical Lithium fluoride </span><span style="mso-bidi-language: FA" lang="EN">chips </span><span lang="EN">(TLD-100) were used.</span></font></p><p style="MARGIN: 0cm 0cm 0pt" class="MatnLatin"><span lang="EN"><font face="Verdana">By using different values of ^99mTc-EC and ^99mTc-DTPA distributed in different phantom parts, the absorbed doses in kidneys, liver, bladder and ovaries were measured. Then by measuring skin dose in the region of kidneys, bladder, liver and ovaries in 20 female patients (10 patients for each radioisotope) that were under renal scan, the absorbed doses of above mentioned organs using phantom results were calculated. Statistical software used was SPSS V.16 and statistical data analysis was done by One sample Kolmogorov-Smirnov and t-tests.</font></span></p><p style="MARGIN: 0cm 0cm 0pt" class="MatnLatin"><font face="Verdana"><b><span lang="EN">Results: </span></b><span lang="EN">The results of skin and organ absorbed doses of kidneys, liver, bladder and ovaries showed a good linear regression. The relationship between organ dose and skin dose with total activity varied linearly. The results of organ absorbed dose in patients that were under renal scan with both radiopharmaceuticals showed:</span></font></p><p style="MARGIN: 0cm 0cm 0pt" class="MatnLatin"><font face="Verdana"><span lang="EN">- Bladder absorbed dose with ^99mTc-DTPA and ^99mTc-EC respectively were:</span><span style="mso-bidi-language: FA" lang="EN"> 4.42</span><span dir="rtl"></span></font><span style="FONT-FAMILY: Arial mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="AR-SA"><span dir="rtl"></span>±</span><span dir="ltr"></span><span lang="EN"><span dir="ltr"></span><font face="Verdana">0.98</font></span><font face="Verdana"><span style="mso-bidi-language: FA" lang="EN"> mrad/mCi</span><span lang="EN">, 2</span><span dir="rtl"></span></font><span style="FONT-FAMILY: Arial mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="AR-SA"><span dir="rtl"></span>.</span><span dir="ltr"></span><span lang="EN"><span dir="ltr"></span><font face="Verdana">91</font></span><span dir="rtl"></span><span style="FONT-FAMILY: Arial mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="AR-SA"><span dir="rtl"></span>±</span><span dir="ltr"></span><span lang="EN"><span dir="ltr"></span><font face="Verdana">0</font></span><span dir="rtl"></span><span style="FONT-FAMILY: Arial mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="AR-SA"><span dir="rtl"></span>.</span><span dir="ltr"></span><span lang="EN"><span dir="ltr"></span><font face="Verdana">74 </font></span><font face="Verdana"><span style="mso-bidi-language: FA" lang="EN">mrad/mCi (p=0</span><span dir="rtl"></span></font><span style="FONT-FAMILY: Arial mso-bidi-language: FA mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="FA"><span dir="rtl"></span>.</span><span dir="ltr"></span><span style="mso-bidi-language: FA" lang="EN"><span dir="ltr"></span><font face="Verdana">001).</font></span><p></p><p style="MARGIN: 0cm 0cm 0pt" class="MatnLatin"><font face="Verdana"><span lang="EN">-Liver absorbed dose with ^99mTc-DTPA and ^99mTc-EC respectively were: </span><span style="mso-bidi-language: FA" lang="EN">2.44</span><span dir="rtl"></span></font><span style="FONT-FAMILY: Arial mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="AR-SA"><span dir="rtl"></span>±</span><span dir="ltr"></span><span lang="EN"><span dir="ltr"></span><font face="Verdana">0.44 </font></span><font face="Verdana"><span style="mso-bidi-language: FA" lang="EN">mrad/mCi, 1.58</span><span dir="rtl"></span></font><span style="FONT-FAMILY: Arial mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="AR-SA"><span dir="rtl"></span>±</span><span dir="ltr"></span><span lang="EN"><span dir="ltr"></span><font face="Verdana">0.019 </font></span><span style="mso-bidi-language: FA" lang="EN"><font face="Verdana">mrad/mCi (p=0.000).</font></span><p></p><p style="MARGIN: 0cm 0cm 0pt" class="MatnLatin"><font face="Verdana"><span lang="EN">-Right kidney absorbed dose with ^99mTc-DTPA and ^99mTc-EC respectively were: 4.04</span><span dir="rtl"></span></font><span style="FONT-FAMILY: Arial mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="AR-SA"><span dir="rtl"></span>±</span><span dir="ltr"></span><span lang="EN"><span dir="ltr"></span><font face="Verdana">1.06 </font></span><font face="Verdana"><span style="mso-bidi-language: FA" lang="EN">mrad/mC</span><span lang="EN">i, 2.67</span><span dir="rtl"></span></font><span style="FONT-FAMILY: Arial mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="AR-SA"><span dir="rtl"></span>±</span><span dir="ltr"></span><span lang="EN"><span dir="ltr"></span><font face="Verdana">0.036 mrad/mCi </font></span><font face="Verdana"><span style="mso-bidi-language: FA" lang="EN">(p=0.003)</span><span lang="EN">.</span></font></p><p style="MARGIN: 0cm 0cm 0pt" class="MatnLatin"><font face="Verdana"><span lang="EN">- Left kidney absorbed dose with ^99mTc-DTPA and ^99mTc-EC respectively were</span><span style="mso-bidi-language: FA" lang="EN">: </span><span lang="EN">4.11</span><span dir="rtl"></span></font><span style="FONT-FAMILY: Arial mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="AR-SA"><span dir="rtl"></span>±</span><span dir="ltr"></span><span lang="EN"><span dir="ltr"></span><font face="Verdana">0.93</font></span><font face="Verdana"><span style="mso-bidi-language: FA" lang="EN"> mrad/mCi, 2.60</span><span dir="rtl"></span></font><span style="FONT-FAMILY: Arial mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="AR-SA"><span dir="rtl"></span>±</span><span dir="ltr"></span><span lang="EN"><span dir="ltr"></span><font face="Verdana">0.14 mrad/mCi </font></span><span style="mso-bidi-language: FA" lang="EN"><font face="Verdana">(p=0.000).</font></span><p></p><p style="MARGIN: 0cm 0cm 0pt" class="MatnLatin"><font face="Verdana"><span lang="EN">-Ovaries absorbed dose with ^99mTc-DTPA and ^99mTc-EC respectively were: </span><span style="mso-bidi-language: FA" lang="EN">2.55</span><span dir="rtl"></span></font><span style="FONT-FAMILY: Arial mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="AR-SA"><span dir="rtl"></span>±</span><span dir="ltr"></span><span lang="EN"><span dir="ltr"></span><font face="Verdana">0.28</font></span><font face="Verdana"><span style="mso-bidi-language: FA" lang="EN"> mrad/mCi, 1.62</span><span dir="rtl"></span></font><span style="FONT-FAMILY: Arial mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="AR-SA"><span dir="rtl"></span>±</span><span dir="ltr"></span><span lang="EN"><span dir="ltr"></span><font face="Verdana">0.025</font></span><font face="Verdana"><span style="mso-bidi-language: FA" lang="EN"> mrad/mCi (p=0</span><span dir="rtl"></span></font><span style="FONT-FAMILY: Arial mso-bidi-language: FA mso-ascii-font-family: Verdana mso-hansi-font-family: Verdana" dir="rtl" lang="FA"><span dir="rtl"></span>.</span><span dir="ltr"></span><span style="mso-bidi-language: FA" lang="EN"><span dir="ltr"></span><font face="Verdana">000). </font></span><p></p><p style="MARGIN: 0cm 0cm 0pt" class="MatnLatin"><font face="Verdana"><b><span style="mso-bidi-language: FA" lang="EN">Conclusion: </span></b><span style="mso-bidi-language: FA" lang="EN">The results of this study showed that in patients under renal scan with ^99mTc-EC, absorbed dose by kidneys, liver, bladder and ovaries is considerably lower than those with ^99mTc-DTPA. Also as ^99mTc-EC has several other advantages such as: easily prepared, cheap, lower hepatic uptake, produces high quality images and has high renal excretion as compared to </span>^{<span lang="EN">99m</span>}<span lang="EN">Tc-DTPA</span><span style="mso-bidi-language: FA" lang="EN">, thus it could be used more in radioisotopic renal scan in nuclear medicine clinics.</span></font><p></p></p><p></p></p><p></p></p><p></p></p><p></p></p><p></p> کلیدواژه‌ها: 1-دوز جذبی اندام‌ها 2-سنتی گرافی کلیه 3-دوزیمتری ترمولومینسانس 4-فنتوم معادل بافت Keywords: 1) Organ absorbed dose 2) Renal scintigraphy 3) Thermoluminescence dosimetry 4) Antropomorphic phantom 33 42 http://rjms.iums.ac.ir/browse.php?a_code=A-10-1-983&slc_lang=fa&sid=1 A.A Sharafi علی‌اکبر شرفی 3900319475328460015978 3900319475328460015978 Yes S Hekmat سپیده حکمت 3900319475328460015979 3900319475328460015979 No T Mortezazadeh توحید مرتضی‌زاده 3900319475328460015980 3900319475328460015980 No M Movahed منصور موحد 3900319475328460015981 3900319475328460015981 No