RT - Journal Article T1 - Developing a Logo Therapy Based Program for Individual with Common Variable Immunodeficiency(CVID): Efficacy on Quality of Life, and Resilience JF - RJMS YR - 2021 JO - RJMS VO - 28 IS - 10 UR - http://rjms.iums.ac.ir/article-1-6796-en.html SP - 12 EP - 24 K1 - program development K1 - Logo therapy K1 - Resilience K1 - Quality of life K1 - Common variable immunodeficiency disease (CVID) AB - Background & Aims: Common Variable Immune Deficiency Disease (CVID) is a group of primary immunodeficiency diseases that is defined as a defect in the functioning of the immune system and is characterized by low levels of immunoglobulin in the blood and an increased incidence of infections. It is a chronic disorder that has no definitive cure and can only be controlled with a blood factor (IVIG) injection. Because of these conditions, patients are affected by a variety of symptoms that limit them. These patients are affected by severe stress and anxiety. This reduces the quality of life and psychological resilience in them. Because this chronic disease affects a person for a long time, its consequences are uncertain, it has high levels of ambiguity in prognosis, and there is no definitive cure. Although medical science has made significant advances in the development of therapies that affect the physical consequences of the disease, facing the consequences of the disease, mental health and emotional adjustment of these patients are the main challenges for the patient and the medical team (9). The important point is that; When suffering from chronic diseases, the psychological factors associated with adaptation in individuals are greatly reduced. Therefore; Positive factors such as resilience, acceptance, life expectancy decrease and also negative factors such as; depression, anxiety and stress increase (10, 11). For this purpose, Logo Therapy was selected as a psychological intervention method and was performed in ten group sessions. The aim of this study was to investigate the effect of group Logo Therapy on increasing resilience and quality of life in CVID patients. Methods: In this study, psychotherapy based on Logo Therapy was developed in 10 group sessions. This online psychotherapy was performed on the experimental group to increase resilience and quality of life of CVID patients and the control group did not receive any intervention and were in contact with the researcher to the extent of informing about the CVID. The statistical population included 32 patients referred to the "Immunodeficiency Research Center of Isfahan University of Medical Sciences" who were randomly divided into experimental and control groups. Logo Therapy helps these patients find meaning and purpose in their suffering and is trained through Logo Therapy techniques to maintain their spirits in the face of difficult and unchangeable conditions and lead a better life. Have. The research protocol is based on the concepts introduced by Victor Frankl and the interpretation of previous protocols. Schulenberg and Hutzel intervention plan was also considered as a research premise (32). In the process of this Logo Therapy, group exercises and homework were developed and presented in order to achieve the following goals: * Helping people to clarify values that have a special meaning to them. * Set reasonable goals for individuals. * Ensuring that people's goals achieve their meaningful personal values. * Practical planning to achieve people's goals and teaching the concept of time in goals. * Identify the strengths and weaknesses of people that affect the achievement of their goals. * Consider the strengths and weaknesses in planning to achieve goals that are in line with people's values. * Teaching Logo Therapy techniques to reduce stress and psychological pressure. The Connor & Davison Resilience Questionnaire (CD_RSC) and the Common Variable Immune Deficiency Quality of Life Questionnaire (CVID_QoL) were used in the pre-test, post-test and one-month follow-up stages of intervention. Results: The data of this study were analyzed by repeated measures analysis of variance using SPSS23 software. The findings showed; Research stages include; Post-test and follow-up in resilience are not generally different from each other, but in the minimum stages of research i.e. post-test and follow-up or the effect of time on resilience in the two groups, the data are different. The difference between the groups in the stages of research on resilience is equal to 27.1%. Logo Therapy in the post-test phase increased the mean resilience scores in the experimental group and the effect of intervention continued in the follow-up phase. According to the results, it can be concluded that the first hypothesis of the research has been confirmed. In other words, Logo Therapy has been effective in increasing resilience in people with CVID. Post-test and follow-up results on quality of life are generally not different from each other, but at least the process of research stages, i.e. post-test and follow-up or the effect of time on quality of life are different in the two groups. The difference between the groups in the stages of research on quality of life is 12.9%, which shows that Logo Therapy in the post-test phase has increased the average scores of quality of life in the experimental group and the effect of intervention in the follow-up phase has continued. According to the mentioned results, the scores of quality of life and resilience in the post-test stage were associated with a significant increase and in the follow-up stage of intervention was relatively stable. (P <0.05). Conclusion: From the findings of this study, it is concluded that Logo Therapy has been effective in increasing resilience and the quality of life of CVID patients. The concepts of Logo Therapy taught to these patients have improved their psychological state. Logotherapy has helped these patients become more resilient in the face of illness by teaching concepts such as finding meaning in suffering and accepting it as part of life. Also, the meaning of life has helped these people to accept the existing problems and experience less stress. This acceptance has increased their quality of life. According to the findings of this study, it is suggested that in addition to medical interventions, Logo Therapy should be used as a psychological intervention to improve the quality of life and resilience of these patients. The goal and mission of medicine and psychology is to increase the quality of life of patients. Coherence of these interventions will have significant effects on improving the condition of CVID patients. LA eng UL http://rjms.iums.ac.ir/article-1-6796-en.html M3 ER -