%0 Journal Article %A Shahsavari, Ronak %A keshavarzi, Fatemeh %T Allelic frequency of rs2070150 polymorphism in patients with type 2 diabetes in a population of Kurdistan province %J Razi Journal of Medical Sciences %V 26 %N 7 %U http://rjms.iums.ac.ir/article-1-5689-en.html %R %D 2019 %K Type 2 diabetes, Polymorphism, ATF6 (rs2070150), %X Background: Type 2 diabetes is a metabolic disorder. Various genetic locations play a role in susceptibility to this disease, including those in the ATF6 (Activating transcription factor. The aim of this study was to investigate the correlation between ATF6 polymorphism (rs2070150) and type 2 diabetes mellitus in patients with type 2 diabetes in Kurdistan. Methods: The present study is a case-control study. A total of 200 blood samples 100 healthy individuals and 100 diabetic patients (age and gender matched)) from the cities of Kurdistan province were screening for ATF6 (rs2070150) polymorphism by Tetra-ARMs PCR method. The obtained data were analyzed using SPSS software and chi-square test. Results: The results showed that 4, 12 and 84 patients, and 3, 26 and 71 healthy controls, respectively, had CC, CG and GG genotypes. Conclusion: GC (%42) Genotype in studied population is a risk factor for type 2 diabetes (p=0.041). %> http://rjms.iums.ac.ir/article-1-5689-en.pdf %P 1-9 %& 1 %! Allelic Frequency of rs2070150 polymorphism in patients with type 2 diabetes in a population of Kurdistan province %9 Research %L A-10-2112-5 %+ Islamic Azad University, Sanandaj, Iran %G eng %@ 2228-7043 %[ 2019