RT - Journal Article T1 - STUDY & DETERMINATION OF NATURAL KILLER CELLS IN THE PERIPHERAL BLOOD OF HEALTHY POPULATION OF IRAN UNIVERSITY OF MEDICAL SCIENCES WITHIN DIFFERENT AGE GROUP(18-60 YEARS) JF - RJMS YR - 2004 JO - RJMS VO - 10 IS - 37 UR - http://rjms.iums.ac.ir/article-1-216-en.html SP - 687 EP - 692 K1 - Key Words: 1) Normal population 2) Natural killer cells 3) Flowcytometry AB - Natural killer(NK) cells are defined as effector cells that have the capacity of spontaneous cytotoxicity toward various target cells and are not major histocompatibility complex(MHC) restricted. NK cells are the first line of immune system defence and serve in surveillance of certain tumor and virus-infected cells. The aim of this study was to determine CD16++CD56+ marker(NK cells) in healthy Iranian population. Peripheral blood samples of 500 male and female subjects, from different age group(18-60 years), were obtained. Flowcytometry technique with dual color monoclonal antibodies (CD16++CD56+) against NK cells was used to analyse the samples. Statistical analysis was done through SPSS software. The mean of CD16+CD56+ was found to be 15.93±7.02 for male and 13.30±5.89 for female population(P LA eng UL http://rjms.iums.ac.ir/article-1-216-en.html M3 ER -