%0 Journal Article %T Vitamin D has an active role in the immune system. This study is aimed to evaluate serum levels of 25-hydroxy vitamin D in children with burns. %J Razi Journal of Medical Sciences %V 22 %N 136 %U http://rjms.iums.ac.ir/article-1-4007-en.html %R %D 2015 %K %X Material and Methods: In this analytical cross-sectional study which was done in children ward of burn injury hospitals in 2012- 2014, 118 patients were studied. A checklist consists of age, sex, the degree burns, entire surface of burn, serum level of 25-OH-VitD, total protein, albumin, phosphorus, calcium, ionized and total calcium and PTH conducted. Data were entered into SPSS v.16 and analyzed. Results: A hundred and eighteen patients (68 (57.6%) male and 50 (42.4%) female) with mean age of 4.04 (SD= 3.04) years old were studied. Mean level of 25-OH-VitD was 14.58 (SD= 6.94) ng/ml. Ninety five (81.35%) had 25-OH-VitD lower than 20 ng/ml and 19 (16.10%) had 25-OH-VitD between 21- 30 ng/ml. We found significant correlation between 25-OH-VitD and total protein, albumin, Ca and significant negative correlation between 25-OH-VitD and body surfac]e area (p Value= 0.001). Discussion: Level of 25-OH-VitD in children after severe burns is low and these patients need to use vitamin D supplement. Level of 25-OH-VitD was not sufficient in 96.61%, while 81.34% had deficiency and 16.10% had insufficiency. %> http://rjms.iums.ac.ir/article-1-4007-en.pdf %P 138-144 %& 138 %! %9 review article %L A-10-1-1730 %+ %G eng %@ 2228-7043 %[ 2015